ANKRD17

 

Full name: ankyrin repeat domain 17 Alias Symbol: GTAR|KIAA0697|FLJ22206|NY-BR-16|MASK2
Type: protein-coding gene Cytoband: 4q13.3
Entrez ID: 26057 HGNC ID: HGNC:23575 Ensembl Gene: ENSG00000132466 OMIM ID: 615929
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ANKRD17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ANKRD17 26057 225852_at 0.3612 0.4792
GSE20347 ANKRD17 26057 212211_at -0.2295 0.0983
GSE23400 ANKRD17 26057 212211_at 0.2307 0.0086
GSE26886 ANKRD17 26057 225852_at 0.5559 0.0113
GSE29001 ANKRD17 26057 212211_at -0.0536 0.7955
GSE38129 ANKRD17 26057 212211_at -0.0661 0.5819
GSE45670 ANKRD17 26057 225852_at 0.0491 0.8003
GSE53622 ANKRD17 26057 21365 0.0137 0.8873
GSE53624 ANKRD17 26057 21365 -0.0727 0.3898
GSE63941 ANKRD17 26057 225852_at -0.7548 0.0204
GSE77861 ANKRD17 26057 225852_at 0.1836 0.5127
GSE97050 ANKRD17 26057 A_24_P220771 -0.0860 0.8233
SRP007169 ANKRD17 26057 RNAseq 0.2110 0.5683
SRP008496 ANKRD17 26057 RNAseq 0.2395 0.2082
SRP064894 ANKRD17 26057 RNAseq 0.0459 0.8340
SRP133303 ANKRD17 26057 RNAseq 0.0870 0.6800
SRP159526 ANKRD17 26057 RNAseq -0.4599 0.0002
SRP193095 ANKRD17 26057 RNAseq -0.1229 0.2217
SRP219564 ANKRD17 26057 RNAseq -0.3514 0.3377
TCGA ANKRD17 26057 RNAseq -0.0261 0.5403

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ANKRD17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ANKRD17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ANKRD17 26057 1 9 20
GSE20123 ANKRD17 26057 1 9 20
GSE43470 ANKRD17 26057 0 13 30
GSE46452 ANKRD17 26057 3 34 22
GSE47630 ANKRD17 26057 1 19 20
GSE54993 ANKRD17 26057 7 0 63
GSE54994 ANKRD17 26057 1 9 43
GSE60625 ANKRD17 26057 0 0 11
GSE74703 ANKRD17 26057 0 11 25
GSE74704 ANKRD17 26057 1 5 14
TCGA ANKRD17 26057 21 25 50

Total number of gains: 36; Total number of losses: 134; Total Number of normals: 318.  


 

Somatic mutations of ANKRD17:

 

Generating mutation plots.

 

Highly correlated genes for ANKRD17:

 

Showing top 20/197 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ANKRD17SURF60.836226303
ANKRD17ELAC20.792775303
ANKRD17MRPS60.792251303
ANKRD17ZNF1210.791647303
ANKRD17GPATCH10.790611303
ANKRD17NOM10.787746303
ANKRD17LTV10.786305303
ANKRD17SRRT0.777521303
ANKRD17SLC25A440.769421303
ANKRD17GTF2H50.758318303
ANKRD17C19orf180.757826303
ANKRD17MRPL90.757542303
ANKRD17ZNF7660.754116303
ANKRD17ZNF3970.753059303
ANKRD17ZNF3620.751695303
ANKRD17ZFYVE270.751511303
ANKRD17ATR0.751183303
ANKRD17KBTBD60.748776303
ANKRD17ZNF1240.746783303
ANKRD17GOLGA8A0.744517303

For details and further investigation, click here