| Full name: protein kinase C and casein kinase substrate in neurons 3 | Alias Symbol: SDPIII | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 29763 | HGNC ID: HGNC:8572 | Ensembl Gene: ENSG00000165912 | OMIM ID: 606513 |
| Drug and gene relationship at DGIdb | |||
Expression of PACSIN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PACSIN3 | 29763 | 218744_s_at | 0.3251 | 0.6333 | |
| GSE20347 | PACSIN3 | 29763 | 218744_s_at | -0.1393 | 0.2404 | |
| GSE23400 | PACSIN3 | 29763 | 218744_s_at | -0.0892 | 0.2438 | |
| GSE26886 | PACSIN3 | 29763 | 218744_s_at | 0.4981 | 0.0009 | |
| GSE29001 | PACSIN3 | 29763 | 218744_s_at | -0.0709 | 0.8027 | |
| GSE38129 | PACSIN3 | 29763 | 218744_s_at | -0.0446 | 0.7697 | |
| GSE45670 | PACSIN3 | 29763 | 218744_s_at | 0.1883 | 0.1515 | |
| GSE53622 | PACSIN3 | 29763 | 4280 | -0.2464 | 0.0244 | |
| GSE53624 | PACSIN3 | 29763 | 4280 | -0.5038 | 0.0000 | |
| GSE63941 | PACSIN3 | 29763 | 218744_s_at | 1.2278 | 0.0122 | |
| GSE77861 | PACSIN3 | 29763 | 218744_s_at | 0.1493 | 0.6078 | |
| GSE97050 | PACSIN3 | 29763 | A_24_P381136 | -0.0974 | 0.6498 | |
| SRP007169 | PACSIN3 | 29763 | RNAseq | -0.9415 | 0.0301 | |
| SRP008496 | PACSIN3 | 29763 | RNAseq | -0.6193 | 0.0489 | |
| SRP064894 | PACSIN3 | 29763 | RNAseq | -0.1816 | 0.5251 | |
| SRP133303 | PACSIN3 | 29763 | RNAseq | -0.8076 | 0.0000 | |
| SRP159526 | PACSIN3 | 29763 | RNAseq | -0.5872 | 0.0463 | |
| SRP193095 | PACSIN3 | 29763 | RNAseq | -0.2633 | 0.2121 | |
| SRP219564 | PACSIN3 | 29763 | RNAseq | -0.4231 | 0.3119 | |
| TCGA | PACSIN3 | 29763 | RNAseq | 0.1358 | 0.0456 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PACSIN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PACSIN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PACSIN3 | 29763 | 3 | 7 | 20 | |
| GSE20123 | PACSIN3 | 29763 | 3 | 6 | 21 | |
| GSE43470 | PACSIN3 | 29763 | 1 | 4 | 38 | |
| GSE46452 | PACSIN3 | 29763 | 8 | 5 | 46 | |
| GSE47630 | PACSIN3 | 29763 | 3 | 9 | 28 | |
| GSE54993 | PACSIN3 | 29763 | 3 | 0 | 67 | |
| GSE54994 | PACSIN3 | 29763 | 1 | 11 | 41 | |
| GSE60625 | PACSIN3 | 29763 | 0 | 0 | 11 | |
| GSE74703 | PACSIN3 | 29763 | 1 | 2 | 33 | |
| GSE74704 | PACSIN3 | 29763 | 2 | 4 | 14 | |
| TCGA | PACSIN3 | 29763 | 10 | 19 | 67 |
Total number of gains: 35; Total number of losses: 67; Total Number of normals: 386.
Somatic mutations of PACSIN3:
Generating mutation plots.
Highly correlated genes for PACSIN3:
Showing top 20/406 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PACSIN3 | SURF6 | 0.820911 | 3 | 0 | 3 |
| PACSIN3 | DDX18 | 0.811866 | 3 | 0 | 3 |
| PACSIN3 | KRTCAP2 | 0.805726 | 3 | 0 | 3 |
| PACSIN3 | RP9 | 0.79506 | 3 | 0 | 3 |
| PACSIN3 | CLK2 | 0.789326 | 3 | 0 | 3 |
| PACSIN3 | UPF1 | 0.775419 | 3 | 0 | 3 |
| PACSIN3 | ACBD6 | 0.764309 | 3 | 0 | 3 |
| PACSIN3 | PUF60 | 0.763555 | 3 | 0 | 3 |
| PACSIN3 | COCH | 0.75535 | 3 | 0 | 3 |
| PACSIN3 | PRR12 | 0.754098 | 3 | 0 | 3 |
| PACSIN3 | CRTC2 | 0.75289 | 3 | 0 | 3 |
| PACSIN3 | SRRT | 0.751516 | 3 | 0 | 3 |
| PACSIN3 | EIF3C | 0.750145 | 3 | 0 | 3 |
| PACSIN3 | XRCC1 | 0.745525 | 3 | 0 | 3 |
| PACSIN3 | ALKBH6 | 0.742225 | 3 | 0 | 3 |
| PACSIN3 | NENF | 0.742151 | 3 | 0 | 3 |
| PACSIN3 | REPS1 | 0.735344 | 3 | 0 | 3 |
| PACSIN3 | FAM193A | 0.730592 | 3 | 0 | 3 |
| PACSIN3 | SLC39A3 | 0.722997 | 3 | 0 | 3 |
| PACSIN3 | DNTTIP1 | 0.721084 | 3 | 0 | 3 |
For details and further investigation, click here
