| Full name: synaptotagmin 12 | Alias Symbol: SRG1 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 91683 | HGNC ID: HGNC:18381 | Ensembl Gene: ENSG00000173227 | OMIM ID: 606436 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT12 | 91683 | 215865_at | 0.0921 | 0.6789 | |
| GSE20347 | SYT12 | 91683 | 215865_at | 0.0823 | 0.5006 | |
| GSE23400 | SYT12 | 91683 | 215865_at | -0.0211 | 0.6286 | |
| GSE26886 | SYT12 | 91683 | 215865_at | 0.2142 | 0.0421 | |
| GSE29001 | SYT12 | 91683 | 215865_at | 0.1532 | 0.4438 | |
| GSE38129 | SYT12 | 91683 | 215865_at | 0.0079 | 0.9427 | |
| GSE45670 | SYT12 | 91683 | 215865_at | 0.1856 | 0.0461 | |
| GSE53622 | SYT12 | 91683 | 121626 | -0.9761 | 0.0000 | |
| GSE53624 | SYT12 | 91683 | 121626 | -1.8898 | 0.0000 | |
| GSE63941 | SYT12 | 91683 | 215865_at | 0.1494 | 0.3603 | |
| GSE77861 | SYT12 | 91683 | 215865_at | 0.0826 | 0.4576 | |
| GSE97050 | SYT12 | 91683 | A_23_P421306 | 0.3990 | 0.6565 | |
| SRP007169 | SYT12 | 91683 | RNAseq | 2.6414 | 0.0011 | |
| SRP064894 | SYT12 | 91683 | RNAseq | 1.4683 | 0.0000 | |
| SRP133303 | SYT12 | 91683 | RNAseq | 1.5169 | 0.0000 | |
| SRP159526 | SYT12 | 91683 | RNAseq | 3.7695 | 0.0000 | |
| SRP219564 | SYT12 | 91683 | RNAseq | 1.2720 | 0.1246 | |
| TCGA | SYT12 | 91683 | RNAseq | 0.9497 | 0.0003 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by SYT12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT12 | 91683 | 9 | 3 | 18 | |
| GSE20123 | SYT12 | 91683 | 9 | 3 | 18 | |
| GSE43470 | SYT12 | 91683 | 6 | 1 | 36 | |
| GSE46452 | SYT12 | 91683 | 12 | 3 | 44 | |
| GSE47630 | SYT12 | 91683 | 9 | 4 | 27 | |
| GSE54993 | SYT12 | 91683 | 3 | 0 | 67 | |
| GSE54994 | SYT12 | 91683 | 13 | 4 | 36 | |
| GSE60625 | SYT12 | 91683 | 0 | 3 | 8 | |
| GSE74703 | SYT12 | 91683 | 4 | 0 | 32 | |
| GSE74704 | SYT12 | 91683 | 7 | 1 | 12 | |
| TCGA | SYT12 | 91683 | 26 | 8 | 62 |
Total number of gains: 98; Total number of losses: 30; Total Number of normals: 360.
Somatic mutations of SYT12:
Generating mutation plots.
Highly correlated genes for SYT12:
Showing top 20/460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT12 | TMPRSS5 | 0.719902 | 6 | 0 | 6 |
| SYT12 | NTNG1 | 0.712323 | 6 | 0 | 6 |
| SYT12 | LUZP4 | 0.71217 | 4 | 0 | 4 |
| SYT12 | IFNA17 | 0.710722 | 4 | 0 | 4 |
| SYT12 | TMEM212 | 0.693648 | 3 | 0 | 3 |
| SYT12 | IFNA7 | 0.681418 | 5 | 0 | 4 |
| SYT12 | CHST5 | 0.676335 | 6 | 0 | 6 |
| SYT12 | ODF1 | 0.667647 | 4 | 0 | 4 |
| SYT12 | CACFD1 | 0.667336 | 4 | 0 | 4 |
| SYT12 | CCR8 | 0.66726 | 5 | 0 | 4 |
| SYT12 | POLR1B | 0.665758 | 5 | 0 | 5 |
| SYT12 | VN1R1 | 0.664814 | 3 | 0 | 3 |
| SYT12 | RBP4 | 0.663077 | 3 | 0 | 3 |
| SYT12 | LINC01361 | 0.660615 | 5 | 0 | 4 |
| SYT12 | SUGCT | 0.659771 | 3 | 0 | 3 |
| SYT12 | OR6A2 | 0.658572 | 6 | 0 | 4 |
| SYT12 | PRLR | 0.656656 | 5 | 0 | 4 |
| SYT12 | TRPM3 | 0.656494 | 5 | 0 | 4 |
| SYT12 | TNFSF8 | 0.656479 | 4 | 0 | 3 |
| SYT12 | TAS2R1 | 0.655293 | 4 | 0 | 4 |
For details and further investigation, click here
