| Full name: transient receptor potential cation channel subfamily M member 3 | Alias Symbol: KIAA1616|LTRPC3|GON-2 | ||
| Type: protein-coding gene | Cytoband: 9q21.12-q21.13 | ||
| Entrez ID: 80036 | HGNC ID: HGNC:17992 | Ensembl Gene: ENSG00000083067 | OMIM ID: 608961 |
| Drug and gene relationship at DGIdb | |||
Expression of TRPM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPM3 | 80036 | 220463_at | 0.1440 | 0.4933 | |
| GSE20347 | TRPM3 | 80036 | 220463_at | 0.0462 | 0.6658 | |
| GSE23400 | TRPM3 | 80036 | 220463_at | -0.0757 | 0.0305 | |
| GSE26886 | TRPM3 | 80036 | 233022_at | 0.1249 | 0.3344 | |
| GSE29001 | TRPM3 | 80036 | 220463_at | -0.0871 | 0.6319 | |
| GSE38129 | TRPM3 | 80036 | 220463_at | -0.1009 | 0.3471 | |
| GSE45670 | TRPM3 | 80036 | 233022_at | 0.0916 | 0.3636 | |
| GSE53622 | TRPM3 | 80036 | 80224 | -0.0010 | 0.9953 | |
| GSE53624 | TRPM3 | 80036 | 80224 | -0.1169 | 0.2620 | |
| GSE63941 | TRPM3 | 80036 | 233022_at | -0.0792 | 0.7320 | |
| GSE77861 | TRPM3 | 80036 | 233022_at | -0.0709 | 0.5503 | |
| GSE97050 | TRPM3 | 80036 | A_24_P392632 | -0.2174 | 0.3559 | |
| SRP133303 | TRPM3 | 80036 | RNAseq | -1.1693 | 0.0033 | |
| SRP159526 | TRPM3 | 80036 | RNAseq | 2.7630 | 0.0018 | |
| TCGA | TRPM3 | 80036 | RNAseq | -3.0619 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by TRPM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPM3 | 80036 | 6 | 10 | 14 | |
| GSE20123 | TRPM3 | 80036 | 6 | 10 | 14 | |
| GSE43470 | TRPM3 | 80036 | 6 | 5 | 32 | |
| GSE46452 | TRPM3 | 80036 | 6 | 14 | 39 | |
| GSE47630 | TRPM3 | 80036 | 1 | 18 | 21 | |
| GSE54993 | TRPM3 | 80036 | 4 | 1 | 65 | |
| GSE54994 | TRPM3 | 80036 | 4 | 13 | 36 | |
| GSE60625 | TRPM3 | 80036 | 0 | 0 | 11 | |
| GSE74703 | TRPM3 | 80036 | 5 | 4 | 27 | |
| GSE74704 | TRPM3 | 80036 | 3 | 7 | 10 | |
| TCGA | TRPM3 | 80036 | 19 | 27 | 50 |
Total number of gains: 60; Total number of losses: 109; Total Number of normals: 319.
Somatic mutations of TRPM3:
Generating mutation plots.
Highly correlated genes for TRPM3:
Showing top 20/912 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPM3 | LIMD1 | 0.81971 | 3 | 0 | 3 |
| TRPM3 | PNPLA2 | 0.781111 | 4 | 0 | 4 |
| TRPM3 | PAX6 | 0.764983 | 4 | 0 | 4 |
| TRPM3 | AQP6 | 0.764127 | 6 | 0 | 6 |
| TRPM3 | KIR3DL3 | 0.754665 | 6 | 0 | 5 |
| TRPM3 | CGA | 0.741812 | 4 | 0 | 3 |
| TRPM3 | AGER | 0.740815 | 3 | 0 | 3 |
| TRPM3 | CEMP1 | 0.735442 | 6 | 0 | 5 |
| TRPM3 | SHANK1 | 0.734975 | 4 | 0 | 4 |
| TRPM3 | CNGB3 | 0.734243 | 6 | 0 | 5 |
| TRPM3 | IL19 | 0.730603 | 3 | 0 | 3 |
| TRPM3 | HECW1 | 0.730141 | 5 | 0 | 4 |
| TRPM3 | PGC | 0.729645 | 4 | 0 | 3 |
| TRPM3 | RAB3IL1 | 0.727463 | 6 | 0 | 5 |
| TRPM3 | PRSS38 | 0.724914 | 3 | 0 | 3 |
| TRPM3 | YY2 | 0.724316 | 3 | 0 | 3 |
| TRPM3 | INSC | 0.723251 | 3 | 0 | 3 |
| TRPM3 | TCP10L | 0.722388 | 4 | 0 | 4 |
| TRPM3 | MYO1A | 0.722112 | 5 | 0 | 5 |
| TRPM3 | NXPH3 | 0.721792 | 4 | 0 | 3 |
For details and further investigation, click here
