| Full name: taste 2 receptor member 1 | Alias Symbol: T2R1|TRB7 | ||
| Type: protein-coding gene | Cytoband: 5p15.31 | ||
| Entrez ID: 50834 | HGNC ID: HGNC:14909 | Ensembl Gene: ENSG00000169777 | OMIM ID: 604796 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAS2R1 | 50834 | 221324_at | -0.2235 | 0.3802 | |
| GSE20347 | TAS2R1 | 50834 | 221324_at | -0.1048 | 0.2776 | |
| GSE23400 | TAS2R1 | 50834 | 221324_at | -0.1065 | 0.0136 | |
| GSE26886 | TAS2R1 | 50834 | 221324_at | -0.1169 | 0.3441 | |
| GSE29001 | TAS2R1 | 50834 | 221324_at | -0.0389 | 0.8808 | |
| GSE38129 | TAS2R1 | 50834 | 221324_at | -0.2151 | 0.0314 | |
| GSE45670 | TAS2R1 | 50834 | 221324_at | -0.0366 | 0.7095 | |
| GSE53622 | TAS2R1 | 50834 | 92299 | 0.1988 | 0.0525 | |
| GSE53624 | TAS2R1 | 50834 | 92299 | 0.1272 | 0.1333 | |
| GSE63941 | TAS2R1 | 50834 | 221324_at | -0.0762 | 0.6256 | |
| GSE77861 | TAS2R1 | 50834 | 221324_at | -0.1022 | 0.3122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAS2R1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R1 | 50834 | 12 | 0 | 18 | |
| GSE20123 | TAS2R1 | 50834 | 12 | 0 | 18 | |
| GSE43470 | TAS2R1 | 50834 | 18 | 0 | 25 | |
| GSE46452 | TAS2R1 | 50834 | 6 | 22 | 31 | |
| GSE47630 | TAS2R1 | 50834 | 6 | 11 | 23 | |
| GSE54993 | TAS2R1 | 50834 | 5 | 5 | 60 | |
| GSE54994 | TAS2R1 | 50834 | 29 | 1 | 23 | |
| GSE60625 | TAS2R1 | 50834 | 0 | 0 | 11 | |
| GSE74703 | TAS2R1 | 50834 | 14 | 0 | 22 | |
| GSE74704 | TAS2R1 | 50834 | 11 | 0 | 9 | |
| TCGA | TAS2R1 | 50834 | 58 | 3 | 35 |
Total number of gains: 171; Total number of losses: 42; Total Number of normals: 275.
Somatic mutations of TAS2R1:
Generating mutation plots.
Highly correlated genes for TAS2R1:
Showing top 20/749 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R1 | KRT38 | 0.742674 | 3 | 0 | 3 |
| TAS2R1 | ADRB3 | 0.713788 | 4 | 0 | 4 |
| TAS2R1 | TRH | 0.691935 | 4 | 0 | 3 |
| TAS2R1 | CST8 | 0.686625 | 3 | 0 | 3 |
| TAS2R1 | CASR | 0.684529 | 3 | 0 | 3 |
| TAS2R1 | MCHR1 | 0.684254 | 3 | 0 | 3 |
| TAS2R1 | KCNJ4 | 0.681334 | 3 | 0 | 3 |
| TAS2R1 | DRD2 | 0.680828 | 4 | 0 | 4 |
| TAS2R1 | UMOD | 0.677665 | 5 | 0 | 5 |
| TAS2R1 | RHAG | 0.67698 | 3 | 0 | 3 |
| TAS2R1 | P2RX6 | 0.676835 | 4 | 0 | 4 |
| TAS2R1 | NTNG1 | 0.676216 | 3 | 0 | 3 |
| TAS2R1 | NPFFR1 | 0.67091 | 3 | 0 | 3 |
| TAS2R1 | EPO | 0.67085 | 4 | 0 | 3 |
| TAS2R1 | GP2 | 0.669524 | 5 | 0 | 3 |
| TAS2R1 | HPX | 0.669488 | 4 | 0 | 4 |
| TAS2R1 | OCM2 | 0.669355 | 4 | 0 | 4 |
| TAS2R1 | PROP1 | 0.668575 | 4 | 0 | 4 |
| TAS2R1 | CIITA | 0.668498 | 6 | 0 | 5 |
| TAS2R1 | NR1I3 | 0.666604 | 5 | 0 | 5 |
For details and further investigation, click here
