| Full name: carbohydrate sulfotransferase 5 | Alias Symbol: I-GLCNAC-6-ST|FLJ22167 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 23563 | HGNC ID: HGNC:1973 | Ensembl Gene: ENSG00000135702 | OMIM ID: 604817 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CHST5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHST5 | 23563 | 221164_x_at | 0.0169 | 0.9479 | |
| GSE20347 | CHST5 | 23563 | 221164_x_at | 0.1790 | 0.0477 | |
| GSE23400 | CHST5 | 23563 | 221164_x_at | 0.0325 | 0.3245 | |
| GSE26886 | CHST5 | 23563 | 223942_x_at | 0.0796 | 0.4591 | |
| GSE29001 | CHST5 | 23563 | 221164_x_at | -0.0468 | 0.8339 | |
| GSE38129 | CHST5 | 23563 | 221164_x_at | 0.0011 | 0.9916 | |
| GSE45670 | CHST5 | 23563 | 223942_x_at | 0.1153 | 0.1912 | |
| GSE63941 | CHST5 | 23563 | 221164_x_at | 0.1855 | 0.1512 | |
| GSE77861 | CHST5 | 23563 | 221164_x_at | 0.0801 | 0.5141 | |
| SRP133303 | CHST5 | 23563 | RNAseq | 0.1865 | 0.4681 | |
| SRP193095 | CHST5 | 23563 | RNAseq | -0.2133 | 0.5258 | |
| SRP219564 | CHST5 | 23563 | RNAseq | -0.1369 | 0.7813 | |
| TCGA | CHST5 | 23563 | RNAseq | -2.0791 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CHST5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CHST5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHST5 | 23563 | 5 | 0 | 25 | |
| GSE20123 | CHST5 | 23563 | 5 | 0 | 25 | |
| GSE43470 | CHST5 | 23563 | 2 | 7 | 34 | |
| GSE46452 | CHST5 | 23563 | 37 | 2 | 20 | |
| GSE47630 | CHST5 | 23563 | 11 | 8 | 21 | |
| GSE54993 | CHST5 | 23563 | 2 | 4 | 64 | |
| GSE54994 | CHST5 | 23563 | 8 | 10 | 35 | |
| GSE60625 | CHST5 | 23563 | 4 | 0 | 7 | |
| GSE74703 | CHST5 | 23563 | 2 | 5 | 29 | |
| GSE74704 | CHST5 | 23563 | 2 | 0 | 18 | |
| TCGA | CHST5 | 23563 | 24 | 15 | 57 |
Total number of gains: 102; Total number of losses: 51; Total Number of normals: 335.
Somatic mutations of CHST5:
Generating mutation plots.
Highly correlated genes for CHST5:
Showing top 20/679 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHST5 | IRF4 | 0.725541 | 3 | 0 | 3 |
| CHST5 | CYSLTR2 | 0.716096 | 5 | 0 | 4 |
| CHST5 | NXPE4 | 0.714561 | 4 | 0 | 4 |
| CHST5 | CIITA | 0.707159 | 4 | 0 | 4 |
| CHST5 | SLCO1C1 | 0.703828 | 4 | 0 | 4 |
| CHST5 | RGS6 | 0.694981 | 4 | 0 | 4 |
| CHST5 | ITGB3 | 0.69492 | 5 | 0 | 5 |
| CHST5 | CHST4 | 0.692699 | 4 | 0 | 3 |
| CHST5 | ERN1 | 0.691684 | 3 | 0 | 3 |
| CHST5 | BCAN | 0.690339 | 6 | 0 | 4 |
| CHST5 | GPA33 | 0.684695 | 5 | 0 | 4 |
| CHST5 | CDC25C | 0.684549 | 3 | 0 | 3 |
| CHST5 | FOXN3-AS2 | 0.684122 | 6 | 0 | 6 |
| CHST5 | OPRM1 | 0.683896 | 4 | 0 | 4 |
| CHST5 | NTNG1 | 0.682877 | 4 | 0 | 4 |
| CHST5 | OR52A1 | 0.682265 | 4 | 0 | 3 |
| CHST5 | TBR1 | 0.681018 | 3 | 0 | 3 |
| CHST5 | EPHB1 | 0.678738 | 4 | 0 | 4 |
| CHST5 | ERCC4 | 0.678586 | 4 | 0 | 3 |
| CHST5 | RGSL1 | 0.67714 | 4 | 0 | 4 |
For details and further investigation, click here
