ODF1

 

Full name: outer dense fiber of sperm tails 1 Alias Symbol: ODFPG|ODF27|RT7|HSPB10|CT133
Type: protein-coding gene Cytoband: 8q22.3
Entrez ID: 4956 HGNC ID: HGNC:8113 Ensembl Gene: ENSG00000155087 OMIM ID: 182878
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ODF1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ODF1 4956 214485_at -0.1682 0.4459
GSE20347 ODF1 4956 214485_at 0.0025 0.9862
GSE23400 ODF1 4956 214485_at -0.1141 0.0011
GSE26886 ODF1 4956 214485_at 0.2635 0.1221
GSE29001 ODF1 4956 214485_at -0.0646 0.7467
GSE38129 ODF1 4956 214485_at -0.0845 0.5032
GSE45670 ODF1 4956 214485_at 0.0343 0.7553
GSE53622 ODF1 4956 16610 -0.1383 0.1129
GSE53624 ODF1 4956 16610 -0.0220 0.6454
GSE63941 ODF1 4956 214485_at 0.2130 0.7415
GSE77861 ODF1 4956 214485_at 0.0277 0.7943

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ODF1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ODF1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ODF1 4956 17 0 13
GSE20123 ODF1 4956 18 0 12
GSE43470 ODF1 4956 22 0 21
GSE46452 ODF1 4956 24 0 35
GSE47630 ODF1 4956 24 0 16
GSE54993 ODF1 4956 0 20 50
GSE54994 ODF1 4956 37 1 15
GSE60625 ODF1 4956 0 4 7
GSE74703 ODF1 4956 19 0 17
GSE74704 ODF1 4956 12 0 8
TCGA ODF1 4956 59 1 36

Total number of gains: 232; Total number of losses: 26; Total Number of normals: 230.  


 

Somatic mutations of ODF1:

 

Generating mutation plots.

 

Highly correlated genes for ODF1:

 

Showing top 20/826 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ODF1PTPRJ0.742243404
ODF1GABRB20.738332404
ODF1JAK30.735486404
ODF1DAB10.730843404
ODF1CYP2A70.728895707
ODF1MVK0.72369505
ODF1IL17A0.718504404
ODF1HRC0.716872404
ODF1RAB3IL10.714226404
ODF1E2F40.713497606
ODF1CTAGE10.71014403
ODF1ADAM220.703835404
ODF1ZNF4600.700872404
ODF1PTPRN20.699323303
ODF1MTAP0.696758504
ODF1ITIH20.696122505
ODF1GP1BA0.695019504
ODF1NUDT70.694596303
ODF1TCP10L0.694152404
ODF1TNFSF80.690923403

For details and further investigation, click here