| Full name: olfactory receptor family 6 subfamily A member 2 | Alias Symbol: OR11-55 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 8590 | HGNC ID: HGNC:15301 | Ensembl Gene: ENSG00000184933 | OMIM ID: 608495 |
| Drug and gene relationship at DGIdb | |||
OR6A2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR6A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR6A2 | 8590 | 221465_at | 0.0118 | 0.9766 | |
| GSE20347 | OR6A2 | 8590 | 221465_at | -0.0084 | 0.9354 | |
| GSE23400 | OR6A2 | 8590 | 221465_at | -0.0868 | 0.0487 | |
| GSE26886 | OR6A2 | 8590 | 221465_at | -0.0518 | 0.6426 | |
| GSE29001 | OR6A2 | 8590 | 221465_at | -0.1531 | 0.3935 | |
| GSE38129 | OR6A2 | 8590 | 221465_at | -0.0723 | 0.4005 | |
| GSE45670 | OR6A2 | 8590 | 221465_at | 0.1220 | 0.2324 | |
| GSE53622 | OR6A2 | 8590 | 13362 | 0.0986 | 0.4013 | |
| GSE53624 | OR6A2 | 8590 | 13362 | -0.1467 | 0.2602 | |
| GSE63941 | OR6A2 | 8590 | 221465_at | 0.0787 | 0.7174 | |
| GSE77861 | OR6A2 | 8590 | 221465_at | -0.0978 | 0.2290 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR6A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR6A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR6A2 | 8590 | 0 | 11 | 19 | |
| GSE20123 | OR6A2 | 8590 | 0 | 11 | 19 | |
| GSE43470 | OR6A2 | 8590 | 1 | 8 | 34 | |
| GSE46452 | OR6A2 | 8590 | 7 | 8 | 44 | |
| GSE47630 | OR6A2 | 8590 | 2 | 12 | 26 | |
| GSE54993 | OR6A2 | 8590 | 3 | 1 | 66 | |
| GSE54994 | OR6A2 | 8590 | 2 | 12 | 39 | |
| GSE60625 | OR6A2 | 8590 | 0 | 0 | 11 | |
| GSE74703 | OR6A2 | 8590 | 1 | 6 | 29 | |
| GSE74704 | OR6A2 | 8590 | 0 | 8 | 12 | |
| TCGA | OR6A2 | 8590 | 9 | 39 | 48 |
Total number of gains: 25; Total number of losses: 116; Total Number of normals: 347.
Somatic mutations of OR6A2:
Generating mutation plots.
Highly correlated genes for OR6A2:
Showing top 20/988 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR6A2 | USP2 | 0.761157 | 4 | 0 | 4 |
| OR6A2 | RNF17 | 0.76015 | 4 | 0 | 4 |
| OR6A2 | ERN1 | 0.758776 | 3 | 0 | 3 |
| OR6A2 | DRD5 | 0.741424 | 4 | 0 | 4 |
| OR6A2 | WNT16 | 0.740845 | 3 | 0 | 3 |
| OR6A2 | OR10J1 | 0.7296 | 5 | 0 | 4 |
| OR6A2 | KRTAP5-8 | 0.719927 | 5 | 0 | 4 |
| OR6A2 | NTNG1 | 0.71868 | 4 | 0 | 4 |
| OR6A2 | KIR2DS2 | 0.717138 | 6 | 0 | 6 |
| OR6A2 | OR2J2 | 0.716995 | 4 | 0 | 4 |
| OR6A2 | CDH7 | 0.715813 | 4 | 0 | 4 |
| OR6A2 | C8A | 0.714565 | 5 | 0 | 5 |
| OR6A2 | RPS6KA6 | 0.709824 | 4 | 0 | 4 |
| OR6A2 | OR1F1 | 0.706786 | 4 | 0 | 4 |
| OR6A2 | DAB1 | 0.705674 | 5 | 0 | 4 |
| OR6A2 | SLC45A2 | 0.700348 | 5 | 0 | 5 |
| OR6A2 | ITGB3 | 0.700189 | 4 | 0 | 4 |
| OR6A2 | GPR31 | 0.698708 | 5 | 0 | 5 |
| OR6A2 | ZNF471 | 0.698496 | 4 | 0 | 4 |
| OR6A2 | HRC | 0.697621 | 3 | 0 | 3 |
For details and further investigation, click here
