| Full name: TNF superfamily member 8 | Alias Symbol: CD153 | ||
| Type: protein-coding gene | Cytoband: 9q32-q33.1 | ||
| Entrez ID: 944 | HGNC ID: HGNC:11938 | Ensembl Gene: ENSG00000106952 | OMIM ID: 603875 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFSF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFSF8 | 944 | 235735_at | -0.2135 | 0.8846 | |
| GSE20347 | TNFSF8 | 944 | 207216_at | 0.0153 | 0.8805 | |
| GSE23400 | TNFSF8 | 944 | 207216_at | -0.1075 | 0.0049 | |
| GSE26886 | TNFSF8 | 944 | 207216_at | -0.0239 | 0.8472 | |
| GSE29001 | TNFSF8 | 944 | 207216_at | -0.1326 | 0.4631 | |
| GSE38129 | TNFSF8 | 944 | 207216_at | -0.1192 | 0.1507 | |
| GSE45670 | TNFSF8 | 944 | 207216_at | -0.0006 | 0.9948 | |
| GSE53622 | TNFSF8 | 944 | 74852 | -0.1777 | 0.3173 | |
| GSE53624 | TNFSF8 | 944 | 74852 | -0.3923 | 0.0311 | |
| GSE63941 | TNFSF8 | 944 | 207216_at | -0.0879 | 0.5435 | |
| GSE77861 | TNFSF8 | 944 | 207216_at | -0.0318 | 0.7193 | |
| GSE97050 | TNFSF8 | 944 | A_23_P169257 | 0.6509 | 0.1663 | |
| SRP007169 | TNFSF8 | 944 | RNAseq | 1.7442 | 0.0599 | |
| SRP064894 | TNFSF8 | 944 | RNAseq | 0.6171 | 0.1000 | |
| SRP133303 | TNFSF8 | 944 | RNAseq | -0.5956 | 0.0080 | |
| SRP159526 | TNFSF8 | 944 | RNAseq | -1.1296 | 0.2655 | |
| SRP193095 | TNFSF8 | 944 | RNAseq | 0.2790 | 0.2812 | |
| SRP219564 | TNFSF8 | 944 | RNAseq | 0.4209 | 0.3921 | |
| TCGA | TNFSF8 | 944 | RNAseq | -0.4854 | 0.1157 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNFSF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFSF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFSF8 | 944 | 5 | 10 | 15 | |
| GSE20123 | TNFSF8 | 944 | 5 | 10 | 15 | |
| GSE43470 | TNFSF8 | 944 | 4 | 3 | 36 | |
| GSE46452 | TNFSF8 | 944 | 6 | 13 | 40 | |
| GSE47630 | TNFSF8 | 944 | 3 | 16 | 21 | |
| GSE54993 | TNFSF8 | 944 | 3 | 3 | 64 | |
| GSE54994 | TNFSF8 | 944 | 9 | 10 | 34 | |
| GSE60625 | TNFSF8 | 944 | 0 | 0 | 11 | |
| GSE74703 | TNFSF8 | 944 | 4 | 3 | 29 | |
| GSE74704 | TNFSF8 | 944 | 2 | 7 | 11 | |
| TCGA | TNFSF8 | 944 | 27 | 21 | 48 |
Total number of gains: 68; Total number of losses: 96; Total Number of normals: 324.
Somatic mutations of TNFSF8:
Generating mutation plots.
Highly correlated genes for TNFSF8:
Showing top 20/773 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFSF8 | TAGAP | 0.830235 | 4 | 0 | 4 |
| TNFSF8 | GIMAP5 | 0.82112 | 3 | 0 | 3 |
| TNFSF8 | APBB1IP | 0.818943 | 5 | 0 | 5 |
| TNFSF8 | EPN1 | 0.808205 | 3 | 0 | 3 |
| TNFSF8 | SNX20 | 0.806221 | 4 | 0 | 4 |
| TNFSF8 | IRF8 | 0.797891 | 5 | 0 | 5 |
| TNFSF8 | GIMAP1 | 0.793134 | 4 | 0 | 4 |
| TNFSF8 | TNFAIP8L2 | 0.78585 | 4 | 0 | 4 |
| TNFSF8 | GAB3 | 0.784777 | 4 | 0 | 4 |
| TNFSF8 | NCKAP1L | 0.777886 | 6 | 0 | 6 |
| TNFSF8 | MPEG1 | 0.775521 | 5 | 0 | 5 |
| TNFSF8 | MAPK11 | 0.770936 | 3 | 0 | 3 |
| TNFSF8 | ARHGAP15 | 0.770387 | 3 | 0 | 3 |
| TNFSF8 | GIMAP7 | 0.768662 | 4 | 0 | 4 |
| TNFSF8 | RCSD1 | 0.768647 | 4 | 0 | 4 |
| TNFSF8 | SLC6A5 | 0.767766 | 3 | 0 | 3 |
| TNFSF8 | SAMD3 | 0.766612 | 4 | 0 | 4 |
| TNFSF8 | GPR34 | 0.764579 | 4 | 0 | 4 |
| TNFSF8 | KIR2DS5 | 0.764496 | 4 | 0 | 4 |
| TNFSF8 | HLA-DPB1 | 0.761257 | 4 | 0 | 4 |
For details and further investigation, click here
