TAS2R50

 

Full name: taste 2 receptor member 50 Alias Symbol: T2R51
Type: protein-coding gene Cytoband: 12p13.2
Entrez ID: 259296 HGNC ID: HGNC:18882 Ensembl Gene: ENSG00000212126 OMIM ID: 609627
Drug and gene relationship at DGIdb

 

Expression of TAS2R50:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TAS2R50 259296 1553561_at -0.0025 0.9941
GSE26886 TAS2R50 259296 1553561_at -0.1078 0.3145
GSE45670 TAS2R50 259296 1553561_at 0.0158 0.8496
GSE53622 TAS2R50 259296 117597 0.8358 0.0000
GSE53624 TAS2R50 259296 117597 0.4878 0.0036
GSE63941 TAS2R50 259296 1553561_at 0.2625 0.1640
GSE77861 TAS2R50 259296 1553561_at -0.0971 0.2959
GSE97050 TAS2R50 259296 A_23_P347029 0.2865 0.2513
SRP133303 TAS2R50 259296 RNAseq 0.4858 0.1284
TCGA TAS2R50 259296 RNAseq -0.8941 0.1933

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TAS2R50 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TAS2R50:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TAS2R50 259296 6 2 22
GSE20123 TAS2R50 259296 6 2 22
GSE43470 TAS2R50 259296 9 3 31
GSE46452 TAS2R50 259296 10 1 48
GSE47630 TAS2R50 259296 14 2 24
GSE54993 TAS2R50 259296 1 10 59
GSE54994 TAS2R50 259296 9 2 42
GSE60625 TAS2R50 259296 0 1 10
GSE74703 TAS2R50 259296 9 2 25
GSE74704 TAS2R50 259296 4 1 15
TCGA TAS2R50 259296 37 8 51

Total number of gains: 105; Total number of losses: 34; Total Number of normals: 349.  


 

Somatic mutations of TAS2R50:

 

Generating mutation plots.

 

Highly correlated genes for TAS2R50:

 

Showing top 20/36 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TAS2R50TAS2R430.879738303
TAS2R50TAS2R190.815264404
TAS2R50TAS2R200.81069303
TAS2R50TAS2R460.81069303
TAS2R50C19orf540.717112303
TAS2R50ACAD110.711354303
TAS2R50ZNF350.706849303
TAS2R50SPDYE10.706249303
TAS2R50ZNF4800.696257303
TAS2R50RBBP50.691387303
TAS2R50ARL17A0.68472303
TAS2R50ALG110.684418303
TAS2R50ZNRD10.683917303
TAS2R50ZNF710.675054303
TAS2R50SPDYE50.66935303
TAS2R50TMEM180.668942303
TAS2R50BTN1A10.662657303
TAS2R50ZNF2480.660877303
TAS2R50CEP570.658554303
TAS2R50DHODH0.653119303

For details and further investigation, click here