TAS2R19

 

Full name: taste 2 receptor member 19 Alias Symbol: T2R19|T2R23
Type: protein-coding gene Cytoband: 12p13.2
Entrez ID: 259294 HGNC ID: HGNC:19108 Ensembl Gene: ENSG00000212124 OMIM ID: 613961
Drug and gene relationship at DGIdb

 

Expression of TAS2R19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TAS2R19 259294 1570384_at 0.0814 0.7559
GSE26886 TAS2R19 259294 1570384_at 0.0264 0.8056
GSE45670 TAS2R19 259294 1570384_at 0.0652 0.3337
GSE53622 TAS2R19 259294 61760 0.7086 0.0000
GSE53624 TAS2R19 259294 61760 0.5262 0.0001
GSE63941 TAS2R19 259294 1570384_at 0.2445 0.1722
GSE77861 TAS2R19 259294 1570384_at 0.0896 0.4409
GSE97050 TAS2R19 259294 A_23_P340308 -0.0211 0.9413
SRP133303 TAS2R19 259294 RNAseq 0.4804 0.0056
SRP193095 TAS2R19 259294 RNAseq 0.1662 0.2902
TCGA TAS2R19 259294 RNAseq -0.3145 0.5285

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TAS2R19 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TAS2R19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TAS2R19 259294 6 2 22
GSE20123 TAS2R19 259294 6 2 22
GSE43470 TAS2R19 259294 9 3 31
GSE46452 TAS2R19 259294 10 1 48
GSE47630 TAS2R19 259294 14 2 24
GSE54993 TAS2R19 259294 1 10 59
GSE54994 TAS2R19 259294 9 2 42
GSE60625 TAS2R19 259294 0 1 10
GSE74703 TAS2R19 259294 9 2 25
GSE74704 TAS2R19 259294 4 1 15
TCGA TAS2R19 259294 38 8 50

Total number of gains: 106; Total number of losses: 34; Total Number of normals: 348.  


 

Somatic mutations of TAS2R19:

 

Generating mutation plots.

 

Highly correlated genes for TAS2R19:

 

Showing top 20/180 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TAS2R19TAS2R430.885842303
TAS2R19TAS2R460.829461303
TAS2R19TAS2R500.815264404
TAS2R19SMC20.814512303
TAS2R19TAS2R200.807431303
TAS2R19GMCL10.804549303
TAS2R19SLC44A10.797251303
TAS2R19DERA0.76889303
TAS2R19TMTC30.76092303
TAS2R19NECAP10.758755303
TAS2R19SFT2D30.754658303
TAS2R19ACAD110.7481303
TAS2R19IDH3A0.747796303
TAS2R19RNGTT0.746288303
TAS2R19NIPA20.739807303
TAS2R19UBE3C0.737567303
TAS2R19DDX200.734559303
TAS2R19B4GALNT40.73451303
TAS2R19SPDYE10.730024303
TAS2R19AEBP20.729985404

For details and further investigation, click here