C19orf54

 

Full name: chromosome 19 open reading frame 54 Alias Symbol: FLJ41131
Type: protein-coding gene Cytoband: 19q13.2
Entrez ID: 284325 HGNC ID: HGNC:24758 Ensembl Gene: ENSG00000188493 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C19orf54:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C19orf54 284325 222052_at -0.1549 0.7071
GSE20347 C19orf54 284325 222052_at 0.4882 0.0007
GSE23400 C19orf54 284325 222052_at 0.3357 0.0000
GSE26886 C19orf54 284325 222052_at 1.3123 0.0000
GSE29001 C19orf54 284325 222052_at 0.3235 0.3811
GSE38129 C19orf54 284325 222052_at 0.4488 0.0001
GSE45670 C19orf54 284325 222052_at 0.2471 0.1014
GSE53622 C19orf54 284325 21378 0.5472 0.0000
GSE53624 C19orf54 284325 35198 0.3582 0.0000
GSE63941 C19orf54 284325 222052_at 0.5139 0.2166
GSE77861 C19orf54 284325 222052_at 0.2196 0.2215
GSE97050 C19orf54 284325 A_33_P3389363 0.5365 0.2050
SRP007169 C19orf54 284325 RNAseq 0.5715 0.3426
SRP064894 C19orf54 284325 RNAseq 1.0610 0.0000
SRP133303 C19orf54 284325 RNAseq 0.2783 0.1665
SRP159526 C19orf54 284325 RNAseq 1.1330 0.0300
SRP193095 C19orf54 284325 RNAseq 0.0757 0.6597
SRP219564 C19orf54 284325 RNAseq 0.5858 0.1209
TCGA C19orf54 284325 RNAseq 0.1041 0.0905

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by C19orf54 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C19orf54:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C19orf54 284325 5 5 20
GSE20123 C19orf54 284325 5 4 21
GSE43470 C19orf54 284325 3 9 31
GSE46452 C19orf54 284325 48 1 10
GSE47630 C19orf54 284325 9 5 26
GSE54993 C19orf54 284325 17 4 49
GSE54994 C19orf54 284325 8 9 36
GSE60625 C19orf54 284325 9 0 2
GSE74703 C19orf54 284325 3 6 27
GSE74704 C19orf54 284325 5 2 13
TCGA C19orf54 284325 14 16 66

Total number of gains: 126; Total number of losses: 61; Total Number of normals: 301.  

 

Somatic mutations of C19orf54:

 

Generating mutation plots.

 

Highly correlated genes for C19orf54:

 

Showing top 20/582 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C19orf54CPSF30.803073303
C19orf54SEMA3C0.796349303
C19orf54FTO0.79326404
C19orf54DNTTIP10.784997404
C19orf54MZF10.776967303
C19orf54NACC10.774077303
C19orf54MED250.770327303
C19orf54RNASEH2C0.77031303
C19orf54TERF20.752952303
C19orf54WDR540.751704404
C19orf54POC50.745483303
C19orf54C9orf160.744354303
C19orf54LRRC8A0.743248303
C19orf54POLR2I0.731434303
C19orf54NOL120.727066303
C19orf54MRPL330.726582303
C19orf54NPFFR10.725886303
C19orf54PTDSS20.721867504
C19orf54POLR2A0.719567303
C19orf54NEU30.717251303

For details and further investigation, click here