| Full name: taste 2 receptor member 43 | Alias Symbol: T2R52 | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 259289 | HGNC ID: HGNC:18875 | Ensembl Gene: ENSG00000255374 | OMIM ID: 612668 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TAS2R43 | 259289 | 74995 | 0.9213 | 0.0000 | |
| GSE53624 | TAS2R43 | 259289 | 74995 | 0.7101 | 0.0000 | |
| GSE97050 | TAS2R43 | 259289 | A_23_P371254 | 0.3137 | 0.2641 | |
| SRP133303 | TAS2R43 | 259289 | RNAseq | 0.5833 | 0.0322 | |
| SRP193095 | TAS2R43 | 259289 | RNAseq | 0.3593 | 0.0300 | |
| TCGA | TAS2R43 | 259289 | RNAseq | 1.2376 | 0.1853 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAS2R43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R43 | 259289 | 6 | 2 | 22 | |
| GSE20123 | TAS2R43 | 259289 | 6 | 2 | 22 | |
| GSE43470 | TAS2R43 | 259289 | 9 | 3 | 31 | |
| GSE46452 | TAS2R43 | 259289 | 10 | 1 | 48 | |
| GSE47630 | TAS2R43 | 259289 | 14 | 2 | 24 | |
| GSE54993 | TAS2R43 | 259289 | 1 | 10 | 59 | |
| GSE54994 | TAS2R43 | 259289 | 9 | 2 | 42 | |
| GSE60625 | TAS2R43 | 259289 | 0 | 1 | 10 | |
| GSE74703 | TAS2R43 | 259289 | 9 | 2 | 25 | |
| GSE74704 | TAS2R43 | 259289 | 4 | 1 | 15 | |
| TCGA | TAS2R43 | 259289 | 38 | 8 | 50 |
Total number of gains: 106; Total number of losses: 34; Total Number of normals: 348.
Somatic mutations of TAS2R43:
Generating mutation plots.
Highly correlated genes for TAS2R43:
Showing top 20/108 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R43 | TAS2R19 | 0.885842 | 3 | 0 | 3 |
| TAS2R43 | TAS2R46 | 0.883827 | 3 | 0 | 3 |
| TAS2R43 | TAS2R50 | 0.879738 | 3 | 0 | 3 |
| TAS2R43 | RAVER1 | 0.816162 | 3 | 0 | 3 |
| TAS2R43 | ALG11 | 0.785549 | 3 | 0 | 3 |
| TAS2R43 | SPDYE1 | 0.785227 | 3 | 0 | 3 |
| TAS2R43 | ZNF248 | 0.771654 | 3 | 0 | 3 |
| TAS2R43 | SLC38A6 | 0.765997 | 3 | 0 | 3 |
| TAS2R43 | CCDC154 | 0.759884 | 3 | 0 | 3 |
| TAS2R43 | SPDYE5 | 0.755812 | 3 | 0 | 3 |
| TAS2R43 | GDF11 | 0.754562 | 3 | 0 | 3 |
| TAS2R43 | GRIA4 | 0.750718 | 3 | 0 | 3 |
| TAS2R43 | ANKRD36B | 0.747999 | 3 | 0 | 3 |
| TAS2R43 | FAM111B | 0.745809 | 3 | 0 | 3 |
| TAS2R43 | SLC26A5 | 0.744516 | 3 | 0 | 3 |
| TAS2R43 | LRCH3 | 0.740032 | 3 | 0 | 3 |
| TAS2R43 | SZT2 | 0.736349 | 3 | 0 | 3 |
| TAS2R43 | ACAD11 | 0.734826 | 3 | 0 | 3 |
| TAS2R43 | TAS2R20 | 0.734658 | 3 | 0 | 3 |
| TAS2R43 | ZNF445 | 0.732104 | 3 | 0 | 3 |
For details and further investigation, click here
