| Full name: RB binding protein 5, histone lysine methyltransferase complex subunit | Alias Symbol: RBQ3|SWD1 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 5929 | HGNC ID: HGNC:9888 | Ensembl Gene: ENSG00000117222 | OMIM ID: 600697 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBBP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBBP5 | 5929 | 205169_at | 0.7673 | 0.0462 | |
| GSE20347 | RBBP5 | 5929 | 205169_at | 0.5715 | 0.0001 | |
| GSE23400 | RBBP5 | 5929 | 205169_at | 0.3177 | 0.0000 | |
| GSE26886 | RBBP5 | 5929 | 205169_at | -0.8118 | 0.0000 | |
| GSE29001 | RBBP5 | 5929 | 205169_at | 0.5122 | 0.0989 | |
| GSE38129 | RBBP5 | 5929 | 205169_at | 0.6477 | 0.0000 | |
| GSE45670 | RBBP5 | 5929 | 205169_at | 0.5362 | 0.0003 | |
| GSE53622 | RBBP5 | 5929 | 64298 | 0.5151 | 0.0000 | |
| GSE53624 | RBBP5 | 5929 | 64298 | 0.4418 | 0.0000 | |
| GSE63941 | RBBP5 | 5929 | 205169_at | -0.4773 | 0.1835 | |
| GSE77861 | RBBP5 | 5929 | 205169_at | 0.5721 | 0.0088 | |
| GSE97050 | RBBP5 | 5929 | A_33_P3235642 | 0.4842 | 0.1857 | |
| SRP007169 | RBBP5 | 5929 | RNAseq | 0.0888 | 0.7809 | |
| SRP008496 | RBBP5 | 5929 | RNAseq | 0.1449 | 0.4893 | |
| SRP064894 | RBBP5 | 5929 | RNAseq | 0.0896 | 0.4674 | |
| SRP133303 | RBBP5 | 5929 | RNAseq | 0.5384 | 0.0001 | |
| SRP159526 | RBBP5 | 5929 | RNAseq | 0.6031 | 0.0145 | |
| SRP193095 | RBBP5 | 5929 | RNAseq | 0.2578 | 0.0000 | |
| SRP219564 | RBBP5 | 5929 | RNAseq | 0.5044 | 0.2208 | |
| TCGA | RBBP5 | 5929 | RNAseq | 0.0438 | 0.4312 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBBP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBBP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBBP5 | 5929 | 11 | 0 | 19 | |
| GSE20123 | RBBP5 | 5929 | 11 | 0 | 19 | |
| GSE43470 | RBBP5 | 5929 | 6 | 0 | 37 | |
| GSE46452 | RBBP5 | 5929 | 3 | 1 | 55 | |
| GSE47630 | RBBP5 | 5929 | 14 | 0 | 26 | |
| GSE54993 | RBBP5 | 5929 | 0 | 6 | 64 | |
| GSE54994 | RBBP5 | 5929 | 15 | 0 | 38 | |
| GSE60625 | RBBP5 | 5929 | 0 | 0 | 11 | |
| GSE74703 | RBBP5 | 5929 | 6 | 0 | 30 | |
| GSE74704 | RBBP5 | 5929 | 5 | 0 | 15 | |
| TCGA | RBBP5 | 5929 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of RBBP5:
Generating mutation plots.
Highly correlated genes for RBBP5:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBBP5 | CHAMP1 | 0.775942 | 3 | 0 | 3 |
| RBBP5 | CENPBD1 | 0.775355 | 3 | 0 | 3 |
| RBBP5 | WDR4 | 0.77324 | 3 | 0 | 3 |
| RBBP5 | ZC3HC1 | 0.765224 | 4 | 0 | 4 |
| RBBP5 | NAA25 | 0.758782 | 4 | 0 | 4 |
| RBBP5 | ZNF680 | 0.729297 | 3 | 0 | 3 |
| RBBP5 | GORAB | 0.728472 | 6 | 0 | 5 |
| RBBP5 | SMCR8 | 0.725069 | 4 | 0 | 4 |
| RBBP5 | PAPOLG | 0.722741 | 5 | 0 | 4 |
| RBBP5 | TMEM138 | 0.721246 | 5 | 0 | 5 |
| RBBP5 | SPATA5 | 0.716283 | 3 | 0 | 3 |
| RBBP5 | RPF2 | 0.714986 | 3 | 0 | 3 |
| RBBP5 | DMTF1 | 0.714663 | 3 | 0 | 3 |
| RBBP5 | ZBTB34 | 0.71215 | 3 | 0 | 3 |
| RBBP5 | SPDYE1 | 0.706337 | 3 | 0 | 3 |
| RBBP5 | POLR1A | 0.701716 | 3 | 0 | 3 |
| RBBP5 | KDM1B | 0.701657 | 5 | 0 | 4 |
| RBBP5 | VMA21 | 0.700211 | 4 | 0 | 3 |
| RBBP5 | PDCD2L | 0.700002 | 4 | 0 | 4 |
| RBBP5 | SLC25A10 | 0.699926 | 3 | 0 | 3 |
For details and further investigation, click here
