| Full name: transmembrane protein 18 | Alias Symbol: DKFZp434C1714|lncND | ||
| Type: protein-coding gene | Cytoband: 2p25.3 | ||
| Entrez ID: 129787 | HGNC ID: HGNC:25257 | Ensembl Gene: ENSG00000151353 | OMIM ID: 613220 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM18 | 129787 | 225489_at | -0.0975 | 0.8173 | |
| GSE26886 | TMEM18 | 129787 | 225489_at | 0.1992 | 0.3186 | |
| GSE45670 | TMEM18 | 129787 | 225489_at | 0.1275 | 0.3850 | |
| GSE53622 | TMEM18 | 129787 | 96158 | -0.0200 | 0.7894 | |
| GSE53624 | TMEM18 | 129787 | 96158 | -0.0420 | 0.4953 | |
| GSE63941 | TMEM18 | 129787 | 225489_at | 0.5391 | 0.1786 | |
| GSE77861 | TMEM18 | 129787 | 225489_at | -0.0594 | 0.7402 | |
| GSE97050 | TMEM18 | 129787 | A_33_P3378031 | 0.0037 | 0.9888 | |
| SRP007169 | TMEM18 | 129787 | RNAseq | -0.4469 | 0.2698 | |
| SRP008496 | TMEM18 | 129787 | RNAseq | -0.1624 | 0.6143 | |
| SRP064894 | TMEM18 | 129787 | RNAseq | -0.0634 | 0.6829 | |
| SRP133303 | TMEM18 | 129787 | RNAseq | 0.0124 | 0.9235 | |
| SRP159526 | TMEM18 | 129787 | RNAseq | 0.3530 | 0.0943 | |
| SRP193095 | TMEM18 | 129787 | RNAseq | -0.1110 | 0.3124 | |
| SRP219564 | TMEM18 | 129787 | RNAseq | 0.3605 | 0.4847 | |
| TCGA | TMEM18 | 129787 | RNAseq | 0.0121 | 0.8312 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM18 | 129787 | 8 | 2 | 20 | |
| GSE20123 | TMEM18 | 129787 | 8 | 2 | 20 | |
| GSE43470 | TMEM18 | 129787 | 3 | 1 | 39 | |
| GSE46452 | TMEM18 | 129787 | 3 | 4 | 52 | |
| GSE47630 | TMEM18 | 129787 | 7 | 0 | 33 | |
| GSE54993 | TMEM18 | 129787 | 1 | 7 | 62 | |
| GSE54994 | TMEM18 | 129787 | 13 | 0 | 40 | |
| GSE60625 | TMEM18 | 129787 | 0 | 3 | 8 | |
| GSE74703 | TMEM18 | 129787 | 3 | 0 | 33 | |
| GSE74704 | TMEM18 | 129787 | 8 | 1 | 11 | |
| TCGA | TMEM18 | 129787 | 31 | 5 | 60 |
Total number of gains: 85; Total number of losses: 25; Total Number of normals: 378.
Somatic mutations of TMEM18:
Generating mutation plots.
Highly correlated genes for TMEM18:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM18 | SP3 | 0.782331 | 3 | 0 | 3 |
| TMEM18 | SUPT7L | 0.780685 | 3 | 0 | 3 |
| TMEM18 | IWS1 | 0.772731 | 3 | 0 | 3 |
| TMEM18 | UXS1 | 0.762955 | 3 | 0 | 3 |
| TMEM18 | RIMKLB | 0.758868 | 3 | 0 | 3 |
| TMEM18 | GTDC1 | 0.75231 | 3 | 0 | 3 |
| TMEM18 | KPNA5 | 0.745804 | 3 | 0 | 3 |
| TMEM18 | CCDC91 | 0.739287 | 3 | 0 | 3 |
| TMEM18 | TBP | 0.739005 | 3 | 0 | 3 |
| TMEM18 | RNASEH2C | 0.729178 | 3 | 0 | 3 |
| TMEM18 | LBR | 0.72762 | 3 | 0 | 3 |
| TMEM18 | TKT | 0.714083 | 4 | 0 | 4 |
| TMEM18 | ERCC3 | 0.710602 | 3 | 0 | 3 |
| TMEM18 | CPSF6 | 0.708797 | 3 | 0 | 3 |
| TMEM18 | MSH6 | 0.708055 | 3 | 0 | 3 |
| TMEM18 | DSCC1 | 0.695644 | 3 | 0 | 3 |
| TMEM18 | RNF121 | 0.693982 | 3 | 0 | 3 |
| TMEM18 | PSPC1 | 0.68664 | 3 | 0 | 3 |
| TMEM18 | ABCC4 | 0.685032 | 3 | 0 | 3 |
| TMEM18 | NIPSNAP1 | 0.682221 | 3 | 0 | 3 |
For details and further investigation, click here
