| Full name: taste 2 receptor member 46 | Alias Symbol: T2R54 | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 259292 | HGNC ID: HGNC:18877 | Ensembl Gene: ENSG00000226761 | OMIM ID: 612774 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TAS2R46 | 259292 | 142148 | 0.8505 | 0.0000 | |
| GSE53624 | TAS2R46 | 259292 | 142148 | 0.6863 | 0.0000 | |
| GSE97050 | TAS2R46 | 259292 | A_23_P376114 | 0.5609 | 0.1496 | |
| SRP133303 | TAS2R46 | 259292 | RNAseq | 0.6671 | 0.0248 | |
| SRP193095 | TAS2R46 | 259292 | RNAseq | 0.0564 | 0.8242 | |
| TCGA | TAS2R46 | 259292 | RNAseq | 0.2776 | 0.7659 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAS2R46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R46 | 259292 | 6 | 2 | 22 | |
| GSE20123 | TAS2R46 | 259292 | 6 | 2 | 22 | |
| GSE43470 | TAS2R46 | 259292 | 9 | 3 | 31 | |
| GSE46452 | TAS2R46 | 259292 | 10 | 1 | 48 | |
| GSE47630 | TAS2R46 | 259292 | 14 | 2 | 24 | |
| GSE54993 | TAS2R46 | 259292 | 1 | 10 | 59 | |
| GSE54994 | TAS2R46 | 259292 | 9 | 2 | 42 | |
| GSE60625 | TAS2R46 | 259292 | 0 | 1 | 10 | |
| GSE74703 | TAS2R46 | 259292 | 9 | 2 | 25 | |
| GSE74704 | TAS2R46 | 259292 | 4 | 1 | 15 | |
| TCGA | TAS2R46 | 259292 | 38 | 8 | 50 |
Total number of gains: 106; Total number of losses: 34; Total Number of normals: 348.
Somatic mutations of TAS2R46:
Generating mutation plots.
Highly correlated genes for TAS2R46:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R46 | TAS2R43 | 0.883827 | 3 | 0 | 3 |
| TAS2R46 | TAS2R19 | 0.829461 | 3 | 0 | 3 |
| TAS2R46 | TAS2R50 | 0.81069 | 3 | 0 | 3 |
| TAS2R46 | RAVER1 | 0.704983 | 3 | 0 | 3 |
| TAS2R46 | TAS2R20 | 0.700706 | 3 | 0 | 3 |
| TAS2R46 | ATXN2L | 0.687782 | 3 | 0 | 3 |
| TAS2R46 | ZNF248 | 0.676569 | 3 | 0 | 3 |
| TAS2R46 | KLHL17 | 0.667805 | 3 | 0 | 3 |
| TAS2R46 | ALG11 | 0.667461 | 3 | 0 | 3 |
| TAS2R46 | SPDYE1 | 0.667112 | 3 | 0 | 3 |
| TAS2R46 | MAZ | 0.666533 | 3 | 0 | 3 |
| TAS2R46 | ADAM8 | 0.662549 | 3 | 0 | 3 |
| TAS2R46 | GDF11 | 0.661045 | 3 | 0 | 3 |
| TAS2R46 | ERCC2 | 0.651023 | 3 | 0 | 3 |
| TAS2R46 | ANKRD36B | 0.648719 | 3 | 0 | 3 |
| TAS2R46 | SLC26A5 | 0.646849 | 3 | 0 | 3 |
| TAS2R46 | ANKRD65 | 0.645105 | 3 | 0 | 3 |
| TAS2R46 | SZT2 | 0.643424 | 3 | 0 | 3 |
| TAS2R46 | SPDYE5 | 0.643323 | 3 | 0 | 3 |
| TAS2R46 | FAM111B | 0.643242 | 3 | 0 | 3 |
For details and further investigation, click here
