| Full name: TBC1 domain family member 12 | Alias Symbol: KIAA0608 | ||
| Type: protein-coding gene | Cytoband: 10q23.33 | ||
| Entrez ID: 23232 | HGNC ID: HGNC:29082 | Ensembl Gene: ENSG00000108239 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D12 | 23232 | 221858_at | -0.1333 | 0.8077 | |
| GSE20347 | TBC1D12 | 23232 | 221858_at | -0.3025 | 0.0329 | |
| GSE23400 | TBC1D12 | 23232 | 221858_at | -0.0028 | 0.9592 | |
| GSE26886 | TBC1D12 | 23232 | 221858_at | -0.8575 | 0.0049 | |
| GSE29001 | TBC1D12 | 23232 | 221858_at | -0.2051 | 0.3592 | |
| GSE38129 | TBC1D12 | 23232 | 221858_at | -0.4228 | 0.0082 | |
| GSE45670 | TBC1D12 | 23232 | 221858_at | -0.6955 | 0.0008 | |
| GSE53622 | TBC1D12 | 23232 | 42774 | -0.4593 | 0.0000 | |
| GSE53624 | TBC1D12 | 23232 | 42774 | -0.4350 | 0.0001 | |
| GSE63941 | TBC1D12 | 23232 | 221858_at | -1.5587 | 0.0004 | |
| GSE77861 | TBC1D12 | 23232 | 221858_at | -0.1157 | 0.4708 | |
| GSE97050 | TBC1D12 | 23232 | A_23_P24215 | -0.0859 | 0.7762 | |
| SRP007169 | TBC1D12 | 23232 | RNAseq | -0.5860 | 0.2019 | |
| SRP008496 | TBC1D12 | 23232 | RNAseq | -0.1946 | 0.4429 | |
| SRP064894 | TBC1D12 | 23232 | RNAseq | -0.2515 | 0.3557 | |
| SRP133303 | TBC1D12 | 23232 | RNAseq | -0.1446 | 0.3578 | |
| SRP159526 | TBC1D12 | 23232 | RNAseq | -0.2639 | 0.4369 | |
| SRP193095 | TBC1D12 | 23232 | RNAseq | -0.2928 | 0.0254 | |
| SRP219564 | TBC1D12 | 23232 | RNAseq | -0.0078 | 0.9824 | |
| TCGA | TBC1D12 | 23232 | RNAseq | -0.3120 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TBC1D12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D12 | 23232 | 1 | 8 | 21 | |
| GSE20123 | TBC1D12 | 23232 | 1 | 7 | 22 | |
| GSE43470 | TBC1D12 | 23232 | 0 | 7 | 36 | |
| GSE46452 | TBC1D12 | 23232 | 0 | 11 | 48 | |
| GSE47630 | TBC1D12 | 23232 | 2 | 14 | 24 | |
| GSE54993 | TBC1D12 | 23232 | 7 | 0 | 63 | |
| GSE54994 | TBC1D12 | 23232 | 2 | 10 | 41 | |
| GSE60625 | TBC1D12 | 23232 | 0 | 0 | 11 | |
| GSE74703 | TBC1D12 | 23232 | 0 | 5 | 31 | |
| GSE74704 | TBC1D12 | 23232 | 0 | 4 | 16 | |
| TCGA | TBC1D12 | 23232 | 6 | 27 | 63 |
Total number of gains: 19; Total number of losses: 93; Total Number of normals: 376.
Somatic mutations of TBC1D12:
Generating mutation plots.
Highly correlated genes for TBC1D12:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D12 | PEX2 | 0.719183 | 3 | 0 | 3 |
| TBC1D12 | TBX5-AS1 | 0.687083 | 3 | 0 | 3 |
| TBC1D12 | ZNF322 | 0.666468 | 3 | 0 | 3 |
| TBC1D12 | UHRF2 | 0.66517 | 3 | 0 | 3 |
| TBC1D12 | LYRM7 | 0.664848 | 5 | 0 | 4 |
| TBC1D12 | PEX11A | 0.652601 | 3 | 0 | 3 |
| TBC1D12 | KIAA2026 | 0.648446 | 3 | 0 | 3 |
| TBC1D12 | INMT | 0.648199 | 3 | 0 | 3 |
| TBC1D12 | SLC19A2 | 0.646479 | 4 | 0 | 4 |
| TBC1D12 | SLC22A15 | 0.645292 | 4 | 0 | 3 |
| TBC1D12 | TTC33 | 0.641367 | 4 | 0 | 4 |
| TBC1D12 | MGARP | 0.640411 | 3 | 0 | 3 |
| TBC1D12 | AMIGO1 | 0.636184 | 3 | 0 | 3 |
| TBC1D12 | ZNF564 | 0.631619 | 3 | 0 | 3 |
| TBC1D12 | SPIN3 | 0.626658 | 3 | 0 | 3 |
| TBC1D12 | SIDT1 | 0.62543 | 3 | 0 | 3 |
| TBC1D12 | SENP8 | 0.624737 | 3 | 0 | 3 |
| TBC1D12 | XPO4 | 0.623635 | 4 | 0 | 4 |
| TBC1D12 | RERE | 0.622288 | 6 | 0 | 5 |
| TBC1D12 | ROCK2 | 0.620992 | 4 | 0 | 4 |
For details and further investigation, click here
