| Full name: peroxisomal biogenesis factor 11 alpha | Alias Symbol: PEX11-ALPHA|MGC119947|MGC138534 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 8800 | HGNC ID: HGNC:8852 | Ensembl Gene: ENSG00000166821 | OMIM ID: 603866 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX11A | 8800 | 205160_at | -0.0373 | 0.9431 | |
| GSE20347 | PEX11A | 8800 | 205160_at | 0.2077 | 0.2317 | |
| GSE23400 | PEX11A | 8800 | 205160_at | -0.1057 | 0.0142 | |
| GSE26886 | PEX11A | 8800 | 205160_at | -0.2152 | 0.3339 | |
| GSE29001 | PEX11A | 8800 | 205160_at | -0.1487 | 0.5198 | |
| GSE38129 | PEX11A | 8800 | 205160_at | -0.0321 | 0.8599 | |
| GSE45670 | PEX11A | 8800 | 205160_at | 0.0022 | 0.9948 | |
| GSE53622 | PEX11A | 8800 | 46498 | -0.2359 | 0.0006 | |
| GSE53624 | PEX11A | 8800 | 46498 | -0.3138 | 0.0000 | |
| GSE63941 | PEX11A | 8800 | 205160_at | 0.1928 | 0.6950 | |
| GSE77861 | PEX11A | 8800 | 205160_at | -0.1966 | 0.2970 | |
| GSE97050 | PEX11A | 8800 | A_23_P37560 | -0.4239 | 0.1921 | |
| SRP007169 | PEX11A | 8800 | RNAseq | -0.6779 | 0.1501 | |
| SRP008496 | PEX11A | 8800 | RNAseq | -0.8992 | 0.0013 | |
| SRP064894 | PEX11A | 8800 | RNAseq | -0.3732 | 0.0469 | |
| SRP133303 | PEX11A | 8800 | RNAseq | -0.0964 | 0.4652 | |
| SRP159526 | PEX11A | 8800 | RNAseq | -0.1634 | 0.5569 | |
| SRP193095 | PEX11A | 8800 | RNAseq | -0.6411 | 0.0000 | |
| SRP219564 | PEX11A | 8800 | RNAseq | -0.0968 | 0.8396 | |
| TCGA | PEX11A | 8800 | RNAseq | -0.3596 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEX11A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX11A | 8800 | 8 | 2 | 20 | |
| GSE20123 | PEX11A | 8800 | 8 | 2 | 20 | |
| GSE43470 | PEX11A | 8800 | 5 | 4 | 34 | |
| GSE46452 | PEX11A | 8800 | 3 | 7 | 49 | |
| GSE47630 | PEX11A | 8800 | 8 | 11 | 21 | |
| GSE54993 | PEX11A | 8800 | 4 | 6 | 60 | |
| GSE54994 | PEX11A | 8800 | 7 | 6 | 40 | |
| GSE60625 | PEX11A | 8800 | 4 | 0 | 7 | |
| GSE74703 | PEX11A | 8800 | 4 | 3 | 29 | |
| GSE74704 | PEX11A | 8800 | 4 | 2 | 14 | |
| TCGA | PEX11A | 8800 | 17 | 12 | 67 |
Total number of gains: 72; Total number of losses: 55; Total Number of normals: 361.
Somatic mutations of PEX11A:
Generating mutation plots.
Highly correlated genes for PEX11A:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX11A | SYF2 | 0.684519 | 3 | 0 | 3 |
| PEX11A | TBC1D12 | 0.652601 | 3 | 0 | 3 |
| PEX11A | USP7 | 0.633679 | 3 | 0 | 3 |
| PEX11A | CAND1 | 0.616847 | 3 | 0 | 3 |
| PEX11A | DBP | 0.613159 | 4 | 0 | 3 |
| PEX11A | NDST2 | 0.588282 | 3 | 0 | 3 |
| PEX11A | ADCYAP1R1 | 0.585399 | 3 | 0 | 3 |
| PEX11A | TRAPPC3 | 0.577344 | 4 | 0 | 3 |
| PEX11A | MAN2A2 | 0.576069 | 7 | 0 | 6 |
| PEX11A | UBE4B | 0.574542 | 5 | 0 | 3 |
| PEX11A | ZACN | 0.568135 | 4 | 0 | 3 |
| PEX11A | COQ7 | 0.566844 | 4 | 0 | 3 |
| PEX11A | LIPT1 | 0.566301 | 5 | 0 | 3 |
| PEX11A | MCCC1 | 0.553357 | 5 | 0 | 3 |
| PEX11A | MRPL46 | 0.546793 | 5 | 0 | 3 |
| PEX11A | IDH2 | 0.54565 | 7 | 0 | 6 |
| PEX11A | AGL | 0.543051 | 4 | 0 | 3 |
| PEX11A | CRTC3 | 0.537716 | 7 | 0 | 4 |
| PEX11A | PARP16 | 0.536742 | 5 | 0 | 3 |
| PEX11A | KBTBD3 | 0.536378 | 5 | 0 | 3 |
For details and further investigation, click here
