| Full name: exportin 4 | Alias Symbol: FLJ13046|KIAA1721 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 64328 | HGNC ID: HGNC:17796 | Ensembl Gene: ENSG00000132953 | OMIM ID: 611449 |
| Drug and gene relationship at DGIdb | |||
Expression of XPO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XPO4 | 64328 | 222649_at | -0.0684 | 0.8832 | |
| GSE20347 | XPO4 | 64328 | 218479_s_at | 0.4257 | 0.0157 | |
| GSE23400 | XPO4 | 64328 | 218479_s_at | 0.1399 | 0.0067 | |
| GSE26886 | XPO4 | 64328 | 222649_at | -0.3285 | 0.1579 | |
| GSE29001 | XPO4 | 64328 | 218479_s_at | 0.5949 | 0.0595 | |
| GSE38129 | XPO4 | 64328 | 218479_s_at | 0.5651 | 0.0004 | |
| GSE45670 | XPO4 | 64328 | 222649_at | -0.0644 | 0.6387 | |
| GSE53622 | XPO4 | 64328 | 63493 | -0.1154 | 0.1230 | |
| GSE53624 | XPO4 | 64328 | 63493 | -0.1518 | 0.1578 | |
| GSE63941 | XPO4 | 64328 | 222649_at | 0.1794 | 0.7165 | |
| GSE77861 | XPO4 | 64328 | 222649_at | 0.0859 | 0.7409 | |
| GSE97050 | XPO4 | 64328 | A_24_P333716 | -0.0370 | 0.8788 | |
| SRP007169 | XPO4 | 64328 | RNAseq | -0.0084 | 0.9815 | |
| SRP008496 | XPO4 | 64328 | RNAseq | 0.1490 | 0.5603 | |
| SRP064894 | XPO4 | 64328 | RNAseq | 0.2130 | 0.3558 | |
| SRP133303 | XPO4 | 64328 | RNAseq | 0.1426 | 0.4102 | |
| SRP159526 | XPO4 | 64328 | RNAseq | -0.2565 | 0.3930 | |
| SRP193095 | XPO4 | 64328 | RNAseq | 0.0358 | 0.7223 | |
| SRP219564 | XPO4 | 64328 | RNAseq | -0.1704 | 0.4416 | |
| TCGA | XPO4 | 64328 | RNAseq | -0.0257 | 0.6357 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by XPO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XPO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XPO4 | 64328 | 1 | 15 | 14 | |
| GSE20123 | XPO4 | 64328 | 1 | 14 | 15 | |
| GSE43470 | XPO4 | 64328 | 2 | 13 | 28 | |
| GSE46452 | XPO4 | 64328 | 0 | 33 | 26 | |
| GSE47630 | XPO4 | 64328 | 3 | 26 | 11 | |
| GSE54993 | XPO4 | 64328 | 11 | 2 | 57 | |
| GSE54994 | XPO4 | 64328 | 1 | 13 | 39 | |
| GSE60625 | XPO4 | 64328 | 0 | 3 | 8 | |
| GSE74703 | XPO4 | 64328 | 2 | 10 | 24 | |
| GSE74704 | XPO4 | 64328 | 0 | 12 | 8 | |
| TCGA | XPO4 | 64328 | 6 | 43 | 47 |
Total number of gains: 27; Total number of losses: 184; Total Number of normals: 277.
Somatic mutations of XPO4:
Generating mutation plots.
Highly correlated genes for XPO4:
Showing top 20/643 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XPO4 | ZBED5 | 0.785208 | 3 | 0 | 3 |
| XPO4 | LRRC42 | 0.784285 | 3 | 0 | 3 |
| XPO4 | PPP1R21 | 0.775039 | 3 | 0 | 3 |
| XPO4 | GNL3 | 0.773184 | 3 | 0 | 3 |
| XPO4 | SPRED2 | 0.752784 | 3 | 0 | 3 |
| XPO4 | RPGR | 0.752741 | 3 | 0 | 3 |
| XPO4 | PDE8A | 0.738456 | 3 | 0 | 3 |
| XPO4 | LYRM7 | 0.737145 | 3 | 0 | 3 |
| XPO4 | CRK | 0.735595 | 3 | 0 | 3 |
| XPO4 | ERP27 | 0.73383 | 3 | 0 | 3 |
| XPO4 | DIS3L | 0.73366 | 4 | 0 | 4 |
| XPO4 | FAM171B | 0.732949 | 3 | 0 | 3 |
| XPO4 | ZNF70 | 0.732504 | 3 | 0 | 3 |
| XPO4 | HOOK3 | 0.73123 | 3 | 0 | 3 |
| XPO4 | SGMS1 | 0.727599 | 4 | 0 | 4 |
| XPO4 | LMBRD2 | 0.727187 | 3 | 0 | 3 |
| XPO4 | RECQL | 0.724194 | 3 | 0 | 3 |
| XPO4 | UBE3A | 0.7235 | 4 | 0 | 3 |
| XPO4 | NAA30 | 0.721503 | 3 | 0 | 3 |
| XPO4 | UBR3 | 0.720561 | 3 | 0 | 3 |
For details and further investigation, click here
