| Full name: ubiquitin like with PHD and ring finger domains 2 | Alias Symbol: RNF107|NIRF|URF2|MGC33463|TDRD23 | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 115426 | HGNC ID: HGNC:12557 | Ensembl Gene: ENSG00000147854 | OMIM ID: 615211 |
| Drug and gene relationship at DGIdb | |||
Expression of UHRF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UHRF2 | 115426 | 225610_at | -0.0528 | 0.9200 | |
| GSE26886 | UHRF2 | 115426 | 225610_at | -0.3376 | 0.0294 | |
| GSE45670 | UHRF2 | 115426 | 225610_at | -0.0739 | 0.7220 | |
| GSE53622 | UHRF2 | 115426 | 93225 | -1.6519 | 0.0000 | |
| GSE53624 | UHRF2 | 115426 | 31167 | -1.6449 | 0.0000 | |
| GSE63941 | UHRF2 | 115426 | 225610_at | -0.1714 | 0.8530 | |
| GSE77861 | UHRF2 | 115426 | 225610_at | -0.0085 | 0.9880 | |
| GSE97050 | UHRF2 | 115426 | A_33_P3279715 | 0.1335 | 0.6529 | |
| SRP007169 | UHRF2 | 115426 | RNAseq | 0.5625 | 0.1874 | |
| SRP008496 | UHRF2 | 115426 | RNAseq | 0.6650 | 0.0145 | |
| SRP064894 | UHRF2 | 115426 | RNAseq | 0.4881 | 0.0138 | |
| SRP133303 | UHRF2 | 115426 | RNAseq | 0.2434 | 0.2043 | |
| SRP159526 | UHRF2 | 115426 | RNAseq | -0.2797 | 0.1567 | |
| SRP193095 | UHRF2 | 115426 | RNAseq | -0.0493 | 0.7025 | |
| SRP219564 | UHRF2 | 115426 | RNAseq | 0.1579 | 0.6087 | |
| TCGA | UHRF2 | 115426 | RNAseq | -0.0029 | 0.9600 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UHRF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UHRF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UHRF2 | 115426 | 1 | 17 | 12 | |
| GSE20123 | UHRF2 | 115426 | 1 | 17 | 12 | |
| GSE43470 | UHRF2 | 115426 | 5 | 11 | 27 | |
| GSE46452 | UHRF2 | 115426 | 2 | 23 | 34 | |
| GSE47630 | UHRF2 | 115426 | 5 | 26 | 9 | |
| GSE54993 | UHRF2 | 115426 | 6 | 3 | 61 | |
| GSE54994 | UHRF2 | 115426 | 9 | 16 | 28 | |
| GSE60625 | UHRF2 | 115426 | 0 | 2 | 9 | |
| GSE74703 | UHRF2 | 115426 | 5 | 8 | 23 | |
| GSE74704 | UHRF2 | 115426 | 0 | 13 | 7 | |
| TCGA | UHRF2 | 115426 | 14 | 51 | 31 |
Total number of gains: 48; Total number of losses: 187; Total Number of normals: 253.
Somatic mutations of UHRF2:
Generating mutation plots.
Highly correlated genes for UHRF2:
Showing top 20/425 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UHRF2 | SOX5 | 0.836918 | 3 | 0 | 3 |
| UHRF2 | B4GALT3 | 0.824539 | 3 | 0 | 3 |
| UHRF2 | CCDC7 | 0.815786 | 3 | 0 | 3 |
| UHRF2 | AKAP17A | 0.800372 | 3 | 0 | 3 |
| UHRF2 | CD38 | 0.795462 | 3 | 0 | 3 |
| UHRF2 | PPWD1 | 0.787759 | 3 | 0 | 3 |
| UHRF2 | CCDC6 | 0.777296 | 4 | 0 | 4 |
| UHRF2 | TSPO | 0.765736 | 3 | 0 | 3 |
| UHRF2 | PTPN21 | 0.759048 | 3 | 0 | 3 |
| UHRF2 | METTL14 | 0.751756 | 3 | 0 | 3 |
| UHRF2 | HIC2 | 0.745335 | 3 | 0 | 3 |
| UHRF2 | CCDC28A | 0.737377 | 3 | 0 | 3 |
| UHRF2 | NAPA | 0.733389 | 3 | 0 | 3 |
| UHRF2 | RORA | 0.733249 | 4 | 0 | 4 |
| UHRF2 | SP1 | 0.733181 | 4 | 0 | 3 |
| UHRF2 | CA13 | 0.731842 | 3 | 0 | 3 |
| UHRF2 | AIDA | 0.730482 | 3 | 0 | 3 |
| UHRF2 | POLR3GL | 0.719415 | 3 | 0 | 3 |
| UHRF2 | AP1G2 | 0.717744 | 3 | 0 | 3 |
| UHRF2 | RSPH3 | 0.717619 | 3 | 0 | 3 |
For details and further investigation, click here
