| Full name: solute carrier family 19 member 2 | Alias Symbol: THTR1 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 10560 | HGNC ID: HGNC:10938 | Ensembl Gene: ENSG00000117479 | OMIM ID: 603941 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC19A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC19A2 | 10560 | 209681_at | -0.2128 | 0.7927 | |
| GSE20347 | SLC19A2 | 10560 | 209681_at | -0.2673 | 0.3485 | |
| GSE23400 | SLC19A2 | 10560 | 209681_at | -0.2631 | 0.0161 | |
| GSE26886 | SLC19A2 | 10560 | 209681_at | 0.6018 | 0.0125 | |
| GSE29001 | SLC19A2 | 10560 | 209681_at | -0.5046 | 0.1702 | |
| GSE38129 | SLC19A2 | 10560 | 209681_at | -0.3418 | 0.0996 | |
| GSE45670 | SLC19A2 | 10560 | 209681_at | -0.2841 | 0.2382 | |
| GSE53622 | SLC19A2 | 10560 | 31469 | -0.7949 | 0.0000 | |
| GSE53624 | SLC19A2 | 10560 | 31469 | -0.6625 | 0.0000 | |
| GSE63941 | SLC19A2 | 10560 | 209681_at | -1.0648 | 0.0574 | |
| GSE77861 | SLC19A2 | 10560 | 209681_at | 0.5344 | 0.4212 | |
| GSE97050 | SLC19A2 | 10560 | A_23_P160466 | -0.5614 | 0.1163 | |
| SRP007169 | SLC19A2 | 10560 | RNAseq | -0.9629 | 0.0801 | |
| SRP008496 | SLC19A2 | 10560 | RNAseq | -0.6160 | 0.0595 | |
| SRP064894 | SLC19A2 | 10560 | RNAseq | -0.7639 | 0.0178 | |
| SRP133303 | SLC19A2 | 10560 | RNAseq | 0.1240 | 0.7312 | |
| SRP159526 | SLC19A2 | 10560 | RNAseq | -0.3594 | 0.2961 | |
| SRP193095 | SLC19A2 | 10560 | RNAseq | -0.2666 | 0.1029 | |
| SRP219564 | SLC19A2 | 10560 | RNAseq | 0.1120 | 0.8194 | |
| TCGA | SLC19A2 | 10560 | RNAseq | -0.4561 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC19A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC19A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC19A2 | 10560 | 11 | 1 | 18 | |
| GSE20123 | SLC19A2 | 10560 | 11 | 1 | 18 | |
| GSE43470 | SLC19A2 | 10560 | 7 | 2 | 34 | |
| GSE46452 | SLC19A2 | 10560 | 3 | 1 | 55 | |
| GSE47630 | SLC19A2 | 10560 | 14 | 0 | 26 | |
| GSE54993 | SLC19A2 | 10560 | 0 | 6 | 64 | |
| GSE54994 | SLC19A2 | 10560 | 16 | 0 | 37 | |
| GSE60625 | SLC19A2 | 10560 | 0 | 0 | 11 | |
| GSE74703 | SLC19A2 | 10560 | 7 | 2 | 27 | |
| GSE74704 | SLC19A2 | 10560 | 5 | 0 | 15 | |
| TCGA | SLC19A2 | 10560 | 43 | 3 | 50 |
Total number of gains: 117; Total number of losses: 16; Total Number of normals: 355.
Somatic mutations of SLC19A2:
Generating mutation plots.
Highly correlated genes for SLC19A2:
Showing top 20/192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC19A2 | PPP1R15B | 0.7369 | 4 | 0 | 4 |
| SLC19A2 | MYH10 | 0.735091 | 3 | 0 | 3 |
| SLC19A2 | VEZT | 0.727663 | 3 | 0 | 3 |
| SLC19A2 | GABBR1 | 0.714895 | 3 | 0 | 3 |
| SLC19A2 | ZNF573 | 0.712877 | 3 | 0 | 3 |
| SLC19A2 | MAP4K3 | 0.712245 | 3 | 0 | 3 |
| SLC19A2 | PCDH7 | 0.710301 | 3 | 0 | 3 |
| SLC19A2 | PDE12 | 0.707628 | 3 | 0 | 3 |
| SLC19A2 | HSF2 | 0.696321 | 3 | 0 | 3 |
| SLC19A2 | GEMIN5 | 0.686733 | 3 | 0 | 3 |
| SLC19A2 | ANKRD10 | 0.683267 | 3 | 0 | 3 |
| SLC19A2 | PGBD1 | 0.683158 | 3 | 0 | 3 |
| SLC19A2 | CEP57 | 0.680386 | 3 | 0 | 3 |
| SLC19A2 | ZNF704 | 0.679822 | 3 | 0 | 3 |
| SLC19A2 | RILPL1 | 0.678468 | 4 | 0 | 3 |
| SLC19A2 | HABP4 | 0.678222 | 4 | 0 | 3 |
| SLC19A2 | SMURF2 | 0.673903 | 4 | 0 | 3 |
| SLC19A2 | SGIP1 | 0.670407 | 4 | 0 | 3 |
| SLC19A2 | LRRN4CL | 0.670232 | 4 | 0 | 4 |
| SLC19A2 | DYNC2H1 | 0.664878 | 3 | 0 | 3 |
For details and further investigation, click here
