| Full name: T-box transcription factor 10 | Alias Symbol: TBX13 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 347853 | HGNC ID: HGNC:11593 | Ensembl Gene: ENSG00000167800 | OMIM ID: 604648 |
| Drug and gene relationship at DGIdb | |||
Expression of TBX10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBX10 | 347853 | 222377_at | -0.0238 | 0.9324 | |
| GSE20347 | TBX10 | 347853 | 222377_at | -0.0176 | 0.8657 | |
| GSE23400 | TBX10 | 347853 | 222377_at | -0.1093 | 0.0003 | |
| GSE26886 | TBX10 | 347853 | 222377_at | 0.3017 | 0.0348 | |
| GSE29001 | TBX10 | 347853 | 222377_at | -0.1940 | 0.2049 | |
| GSE38129 | TBX10 | 347853 | 222377_at | -0.0722 | 0.3870 | |
| GSE45670 | TBX10 | 347853 | 207689_at | -0.0119 | 0.9123 | |
| GSE53622 | TBX10 | 347853 | 25301 | 0.0429 | 0.5121 | |
| GSE53624 | TBX10 | 347853 | 25301 | -0.1939 | 0.0293 | |
| GSE63941 | TBX10 | 347853 | 222377_at | 0.2685 | 0.0495 | |
| GSE77861 | TBX10 | 347853 | 222377_at | -0.0062 | 0.9649 | |
| GSE97050 | TBX10 | 347853 | A_32_P538017 | 0.0623 | 0.7735 | |
| TCGA | TBX10 | 347853 | RNAseq | 0.1240 | 0.9082 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBX10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBX10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBX10 | 347853 | 10 | 3 | 17 | |
| GSE20123 | TBX10 | 347853 | 10 | 3 | 17 | |
| GSE43470 | TBX10 | 347853 | 5 | 2 | 36 | |
| GSE46452 | TBX10 | 347853 | 14 | 3 | 42 | |
| GSE47630 | TBX10 | 347853 | 8 | 5 | 27 | |
| GSE54993 | TBX10 | 347853 | 3 | 1 | 66 | |
| GSE54994 | TBX10 | 347853 | 13 | 4 | 36 | |
| GSE60625 | TBX10 | 347853 | 0 | 3 | 8 | |
| GSE74703 | TBX10 | 347853 | 4 | 1 | 31 | |
| GSE74704 | TBX10 | 347853 | 8 | 1 | 11 | |
| TCGA | TBX10 | 347853 | 36 | 9 | 51 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of TBX10:
Generating mutation plots.
Highly correlated genes for TBX10:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBX10 | GALR2 | 0.824548 | 3 | 0 | 3 |
| TBX10 | C1QTNF6 | 0.778128 | 3 | 0 | 3 |
| TBX10 | PABPN1L | 0.732938 | 3 | 0 | 3 |
| TBX10 | OR2A5 | 0.727835 | 3 | 0 | 3 |
| TBX10 | GPR150 | 0.727048 | 4 | 0 | 4 |
| TBX10 | SPINT3 | 0.726802 | 5 | 0 | 5 |
| TBX10 | FOLH1 | 0.723067 | 6 | 0 | 6 |
| TBX10 | ZNF687 | 0.718746 | 3 | 0 | 3 |
| TBX10 | STK32C | 0.713222 | 3 | 0 | 3 |
| TBX10 | ATXN7L2 | 0.707591 | 3 | 0 | 3 |
| TBX10 | SERTM1 | 0.706965 | 4 | 0 | 3 |
| TBX10 | TMEM37 | 0.70377 | 3 | 0 | 3 |
| TBX10 | ATAD3C | 0.700917 | 4 | 0 | 4 |
| TBX10 | ZNF524 | 0.699577 | 5 | 0 | 4 |
| TBX10 | C16orf71 | 0.697017 | 3 | 0 | 3 |
| TBX10 | PHF7 | 0.691992 | 7 | 0 | 7 |
| TBX10 | HK3 | 0.690382 | 4 | 0 | 4 |
| TBX10 | ZMYND15 | 0.689049 | 3 | 0 | 3 |
| TBX10 | KHDRBS2 | 0.68831 | 4 | 0 | 4 |
| TBX10 | VIPR2 | 0.688238 | 5 | 0 | 5 |
For details and further investigation, click here
