| Full name: vasoactive intestinal peptide receptor 2 | Alias Symbol: VPAC2|VPAC2R | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 7434 | HGNC ID: HGNC:12695 | Ensembl Gene: ENSG00000106018 | OMIM ID: 601970 |
| Drug and gene relationship at DGIdb | |||
VIPR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway |
Expression of VIPR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VIPR2 | 7434 | 211598_x_at | -0.1937 | 0.6056 | |
| GSE20347 | VIPR2 | 7434 | 205946_at | -0.0681 | 0.5293 | |
| GSE23400 | VIPR2 | 7434 | 205946_at | -0.2504 | 0.0000 | |
| GSE26886 | VIPR2 | 7434 | 205946_at | -0.0042 | 0.9823 | |
| GSE29001 | VIPR2 | 7434 | 205946_at | -0.2082 | 0.3381 | |
| GSE38129 | VIPR2 | 7434 | 205946_at | -0.3329 | 0.0032 | |
| GSE45670 | VIPR2 | 7434 | 205946_at | -0.0838 | 0.3565 | |
| GSE53622 | VIPR2 | 7434 | 92332 | -1.2777 | 0.0000 | |
| GSE53624 | VIPR2 | 7434 | 92332 | -0.6019 | 0.0000 | |
| GSE63941 | VIPR2 | 7434 | 205946_at | -0.6529 | 0.0006 | |
| GSE77861 | VIPR2 | 7434 | 205946_at | -0.0874 | 0.3672 | |
| GSE97050 | VIPR2 | 7434 | A_32_P153071 | -0.1962 | 0.5830 | |
| SRP064894 | VIPR2 | 7434 | RNAseq | -0.1653 | 0.7661 | |
| SRP133303 | VIPR2 | 7434 | RNAseq | -1.5662 | 0.0000 | |
| SRP159526 | VIPR2 | 7434 | RNAseq | -1.6082 | 0.0008 | |
| SRP219564 | VIPR2 | 7434 | RNAseq | -0.1498 | 0.8934 | |
| TCGA | VIPR2 | 7434 | RNAseq | -2.4185 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by VIPR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VIPR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VIPR2 | 7434 | 3 | 3 | 24 | |
| GSE20123 | VIPR2 | 7434 | 2 | 3 | 25 | |
| GSE43470 | VIPR2 | 7434 | 2 | 5 | 36 | |
| GSE46452 | VIPR2 | 7434 | 7 | 2 | 50 | |
| GSE47630 | VIPR2 | 7434 | 6 | 9 | 25 | |
| GSE54993 | VIPR2 | 7434 | 3 | 3 | 64 | |
| GSE54994 | VIPR2 | 7434 | 8 | 9 | 36 | |
| GSE60625 | VIPR2 | 7434 | 0 | 0 | 11 | |
| GSE74703 | VIPR2 | 7434 | 2 | 4 | 30 | |
| GSE74704 | VIPR2 | 7434 | 1 | 3 | 16 | |
| TCGA | VIPR2 | 7434 | 28 | 26 | 42 |
Total number of gains: 62; Total number of losses: 67; Total Number of normals: 359.
Somatic mutations of VIPR2:
Generating mutation plots.
Highly correlated genes for VIPR2:
Showing top 20/999 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VIPR2 | PRKAR1B | 0.813395 | 3 | 0 | 3 |
| VIPR2 | ANKRD33B | 0.770473 | 3 | 0 | 3 |
| VIPR2 | GPR146 | 0.75341 | 3 | 0 | 3 |
| VIPR2 | ZC3H6 | 0.732151 | 4 | 0 | 4 |
| VIPR2 | ABCC6 | 0.722243 | 3 | 0 | 3 |
| VIPR2 | CELF4 | 0.721092 | 3 | 0 | 3 |
| VIPR2 | MOB2 | 0.721022 | 3 | 0 | 3 |
| VIPR2 | C1QTNF2 | 0.715815 | 3 | 0 | 3 |
| VIPR2 | ASB10 | 0.711255 | 4 | 0 | 3 |
| VIPR2 | RUSC1 | 0.711069 | 3 | 0 | 3 |
| VIPR2 | NXPH3 | 0.708574 | 9 | 0 | 8 |
| VIPR2 | EYS | 0.706611 | 3 | 0 | 3 |
| VIPR2 | AVPR1B | 0.705739 | 6 | 0 | 6 |
| VIPR2 | ENGASE | 0.704782 | 3 | 0 | 3 |
| VIPR2 | FZD9 | 0.702411 | 3 | 0 | 3 |
| VIPR2 | SYT2 | 0.701734 | 8 | 0 | 7 |
| VIPR2 | RHAG | 0.697828 | 3 | 0 | 3 |
| VIPR2 | PRKCG | 0.697644 | 3 | 0 | 3 |
| VIPR2 | HRC | 0.695038 | 8 | 0 | 8 |
| VIPR2 | TRIM10 | 0.690837 | 7 | 0 | 7 |
For details and further investigation, click here
