| Full name: transmembrane protein 37 | Alias Symbol: PR1|PR | ||
| Type: protein-coding gene | Cytoband: 2q14.2 | ||
| Entrez ID: 140738 | HGNC ID: HGNC:18216 | Ensembl Gene: ENSG00000171227 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM37 | 140738 | 1554483_at | -0.1755 | 0.5827 | |
| GSE26886 | TMEM37 | 140738 | 227190_at | 0.1490 | 0.7028 | |
| GSE45670 | TMEM37 | 140738 | 1554483_at | -0.0516 | 0.7525 | |
| GSE53622 | TMEM37 | 140738 | 62403 | -0.6130 | 0.0017 | |
| GSE53624 | TMEM37 | 140738 | 62403 | -0.5990 | 0.0000 | |
| GSE63941 | TMEM37 | 140738 | 1554483_at | 0.5534 | 0.3070 | |
| GSE77861 | TMEM37 | 140738 | 243849_at | -0.2195 | 0.0933 | |
| GSE97050 | TMEM37 | 140738 | A_33_P3224780 | 0.0545 | 0.8414 | |
| SRP007169 | TMEM37 | 140738 | RNAseq | -1.0191 | 0.0298 | |
| SRP008496 | TMEM37 | 140738 | RNAseq | -0.9382 | 0.0128 | |
| SRP064894 | TMEM37 | 140738 | RNAseq | -0.6727 | 0.0480 | |
| SRP133303 | TMEM37 | 140738 | RNAseq | -0.1177 | 0.7538 | |
| SRP159526 | TMEM37 | 140738 | RNAseq | 0.2030 | 0.7707 | |
| SRP193095 | TMEM37 | 140738 | RNAseq | -0.2807 | 0.3824 | |
| SRP219564 | TMEM37 | 140738 | RNAseq | -1.0491 | 0.1376 | |
| TCGA | TMEM37 | 140738 | RNAseq | -0.4912 | 0.0137 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM37 | 140738 | 6 | 1 | 23 | |
| GSE20123 | TMEM37 | 140738 | 6 | 1 | 23 | |
| GSE43470 | TMEM37 | 140738 | 3 | 1 | 39 | |
| GSE46452 | TMEM37 | 140738 | 1 | 4 | 54 | |
| GSE47630 | TMEM37 | 140738 | 6 | 0 | 34 | |
| GSE54993 | TMEM37 | 140738 | 0 | 6 | 64 | |
| GSE54994 | TMEM37 | 140738 | 12 | 0 | 41 | |
| GSE60625 | TMEM37 | 140738 | 0 | 3 | 8 | |
| GSE74703 | TMEM37 | 140738 | 3 | 1 | 32 | |
| GSE74704 | TMEM37 | 140738 | 3 | 1 | 16 | |
| TCGA | TMEM37 | 140738 | 32 | 6 | 58 |
Total number of gains: 72; Total number of losses: 24; Total Number of normals: 392.
Somatic mutations of TMEM37:
Generating mutation plots.
Highly correlated genes for TMEM37:
Showing top 20/124 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM37 | DNAH6 | 0.806887 | 3 | 0 | 3 |
| TMEM37 | KCNT1 | 0.795353 | 3 | 0 | 3 |
| TMEM37 | OR1J4 | 0.753684 | 3 | 0 | 3 |
| TMEM37 | INO80C | 0.74716 | 3 | 0 | 3 |
| TMEM37 | CABP7 | 0.744993 | 3 | 0 | 3 |
| TMEM37 | CCDC114 | 0.741824 | 3 | 0 | 3 |
| TMEM37 | POU4F3 | 0.739294 | 3 | 0 | 3 |
| TMEM37 | CATSPER3 | 0.736727 | 3 | 0 | 3 |
| TMEM37 | ROM1 | 0.734762 | 3 | 0 | 3 |
| TMEM37 | RXFP3 | 0.728599 | 3 | 0 | 3 |
| TMEM37 | SEC13 | 0.726484 | 3 | 0 | 3 |
| TMEM37 | PEX11G | 0.725497 | 3 | 0 | 3 |
| TMEM37 | CLCN1 | 0.721746 | 3 | 0 | 3 |
| TMEM37 | NT5C1A | 0.721117 | 3 | 0 | 3 |
| TMEM37 | DNAJC17 | 0.713012 | 3 | 0 | 3 |
| TMEM37 | TBX10 | 0.70377 | 3 | 0 | 3 |
| TMEM37 | DRD4 | 0.700496 | 3 | 0 | 3 |
| TMEM37 | TMEM184A | 0.695542 | 3 | 0 | 3 |
| TMEM37 | EFNA2 | 0.693925 | 3 | 0 | 3 |
| TMEM37 | EXOSC7 | 0.691878 | 3 | 0 | 3 |
For details and further investigation, click here
