| Full name: tectonic family member 2 | Alias Symbol: FLJ12975|TECT2|MKS8|JBTS24 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 79867 | HGNC ID: HGNC:25774 | Ensembl Gene: ENSG00000168778 | OMIM ID: 613846 |
| Drug and gene relationship at DGIdb | |||
Expression of TCTN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCTN2 | 79867 | 206438_x_at | -0.2786 | 0.2471 | |
| GSE20347 | TCTN2 | 79867 | 206438_x_at | 0.1830 | 0.2019 | |
| GSE23400 | TCTN2 | 79867 | 206438_x_at | 0.0553 | 0.1165 | |
| GSE26886 | TCTN2 | 79867 | 206438_x_at | 0.3160 | 0.0426 | |
| GSE29001 | TCTN2 | 79867 | 206438_x_at | -0.2244 | 0.2456 | |
| GSE38129 | TCTN2 | 79867 | 206438_x_at | -0.0083 | 0.9556 | |
| GSE45670 | TCTN2 | 79867 | 206438_x_at | -0.0570 | 0.5515 | |
| GSE53622 | TCTN2 | 79867 | 97284 | 0.7567 | 0.0000 | |
| GSE53624 | TCTN2 | 79867 | 97284 | 0.7257 | 0.0000 | |
| GSE63941 | TCTN2 | 79867 | 206438_x_at | 0.8577 | 0.0015 | |
| GSE77861 | TCTN2 | 79867 | 206438_x_at | 0.0059 | 0.9748 | |
| GSE97050 | TCTN2 | 79867 | A_23_P64712 | 0.2139 | 0.2585 | |
| SRP007169 | TCTN2 | 79867 | RNAseq | 2.2439 | 0.0025 | |
| SRP008496 | TCTN2 | 79867 | RNAseq | 2.1838 | 0.0002 | |
| SRP064894 | TCTN2 | 79867 | RNAseq | 0.6592 | 0.0002 | |
| SRP133303 | TCTN2 | 79867 | RNAseq | 0.3452 | 0.0845 | |
| SRP159526 | TCTN2 | 79867 | RNAseq | 1.4412 | 0.0048 | |
| SRP193095 | TCTN2 | 79867 | RNAseq | 0.6499 | 0.0000 | |
| SRP219564 | TCTN2 | 79867 | RNAseq | 0.3375 | 0.3052 | |
| TCGA | TCTN2 | 79867 | RNAseq | 0.1769 | 0.0468 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TCTN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCTN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCTN2 | 79867 | 5 | 5 | 20 | |
| GSE20123 | TCTN2 | 79867 | 5 | 5 | 20 | |
| GSE43470 | TCTN2 | 79867 | 2 | 1 | 40 | |
| GSE46452 | TCTN2 | 79867 | 9 | 1 | 49 | |
| GSE47630 | TCTN2 | 79867 | 9 | 3 | 28 | |
| GSE54993 | TCTN2 | 79867 | 0 | 5 | 65 | |
| GSE54994 | TCTN2 | 79867 | 4 | 8 | 41 | |
| GSE60625 | TCTN2 | 79867 | 0 | 0 | 11 | |
| GSE74703 | TCTN2 | 79867 | 2 | 0 | 34 | |
| GSE74704 | TCTN2 | 79867 | 3 | 3 | 14 | |
| TCGA | TCTN2 | 79867 | 21 | 11 | 64 |
Total number of gains: 60; Total number of losses: 42; Total Number of normals: 386.
Somatic mutations of TCTN2:
Generating mutation plots.
Highly correlated genes for TCTN2:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCTN2 | OR10J1 | 0.726439 | 3 | 0 | 3 |
| TCTN2 | GALNT8 | 0.700981 | 4 | 0 | 4 |
| TCTN2 | TMEM107 | 0.699283 | 4 | 0 | 4 |
| TCTN2 | CNTN2 | 0.698391 | 3 | 0 | 3 |
| TCTN2 | TAT | 0.697154 | 3 | 0 | 3 |
| TCTN2 | PIP5K1B | 0.695692 | 3 | 0 | 3 |
| TCTN2 | TCL1B | 0.692174 | 4 | 0 | 4 |
| TCTN2 | PRR34 | 0.690458 | 4 | 0 | 4 |
| TCTN2 | RNF185-AS1 | 0.688197 | 4 | 0 | 3 |
| TCTN2 | CACNA1F | 0.687891 | 3 | 0 | 3 |
| TCTN2 | CGA | 0.68697 | 3 | 0 | 3 |
| TCTN2 | C11orf68 | 0.684852 | 3 | 0 | 3 |
| TCTN2 | LINC01136 | 0.676098 | 5 | 0 | 5 |
| TCTN2 | IFNA7 | 0.675885 | 3 | 0 | 3 |
| TCTN2 | ITGB3 | 0.675717 | 4 | 0 | 4 |
| TCTN2 | SIGLEC6 | 0.674157 | 3 | 0 | 3 |
| TCTN2 | CA1 | 0.670459 | 5 | 0 | 5 |
| TCTN2 | C9orf16 | 0.669744 | 4 | 0 | 4 |
| TCTN2 | GDF3 | 0.667381 | 3 | 0 | 3 |
| TCTN2 | ZNF837 | 0.666543 | 3 | 0 | 3 |
For details and further investigation, click here
