| Full name: transmembrane protein 107 | Alias Symbol: MGC10744 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 84314 | HGNC ID: HGNC:28128 | Ensembl Gene: ENSG00000179029 | OMIM ID: 616183 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM107:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM107 | 84314 | 238590_x_at | -0.1475 | 0.5411 | |
| GSE26886 | TMEM107 | 84314 | 238590_x_at | -0.0192 | 0.9371 | |
| GSE45670 | TMEM107 | 84314 | 238590_x_at | 0.4680 | 0.0151 | |
| GSE53622 | TMEM107 | 84314 | 95943 | 0.1664 | 0.0688 | |
| GSE53624 | TMEM107 | 84314 | 95943 | 0.4316 | 0.0000 | |
| GSE63941 | TMEM107 | 84314 | 238590_x_at | 1.2204 | 0.0204 | |
| GSE77861 | TMEM107 | 84314 | 238590_x_at | 0.2272 | 0.5199 | |
| GSE97050 | TMEM107 | 84314 | A_24_P284353 | 0.1671 | 0.4598 | |
| SRP007169 | TMEM107 | 84314 | RNAseq | -0.8769 | 0.0825 | |
| SRP008496 | TMEM107 | 84314 | RNAseq | -0.6593 | 0.0161 | |
| SRP064894 | TMEM107 | 84314 | RNAseq | 0.5375 | 0.0173 | |
| SRP133303 | TMEM107 | 84314 | RNAseq | -0.0141 | 0.9435 | |
| SRP159526 | TMEM107 | 84314 | RNAseq | 0.2743 | 0.2407 | |
| SRP193095 | TMEM107 | 84314 | RNAseq | 0.4228 | 0.0161 | |
| SRP219564 | TMEM107 | 84314 | RNAseq | -0.3831 | 0.2195 | |
| TCGA | TMEM107 | 84314 | RNAseq | 0.3455 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM107 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM107:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM107 | 84314 | 4 | 2 | 24 | |
| GSE20123 | TMEM107 | 84314 | 4 | 3 | 23 | |
| GSE43470 | TMEM107 | 84314 | 1 | 6 | 36 | |
| GSE46452 | TMEM107 | 84314 | 34 | 1 | 24 | |
| GSE47630 | TMEM107 | 84314 | 7 | 1 | 32 | |
| GSE54993 | TMEM107 | 84314 | 4 | 3 | 63 | |
| GSE54994 | TMEM107 | 84314 | 5 | 8 | 40 | |
| GSE60625 | TMEM107 | 84314 | 4 | 0 | 7 | |
| GSE74703 | TMEM107 | 84314 | 1 | 3 | 32 | |
| GSE74704 | TMEM107 | 84314 | 2 | 1 | 17 | |
| TCGA | TMEM107 | 84314 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of TMEM107:
Generating mutation plots.
Highly correlated genes for TMEM107:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM107 | ERG | 0.766174 | 3 | 0 | 3 |
| TMEM107 | TMEM173 | 0.751639 | 3 | 0 | 3 |
| TMEM107 | CDK5RAP2 | 0.747503 | 3 | 0 | 3 |
| TMEM107 | EIF2B2 | 0.741904 | 3 | 0 | 3 |
| TMEM107 | DNAH1 | 0.741339 | 3 | 0 | 3 |
| TMEM107 | CD93 | 0.736084 | 3 | 0 | 3 |
| TMEM107 | SLC28A3 | 0.733914 | 3 | 0 | 3 |
| TMEM107 | RLF | 0.731867 | 3 | 0 | 3 |
| TMEM107 | GPHN | 0.715267 | 3 | 0 | 3 |
| TMEM107 | MPI | 0.714706 | 3 | 0 | 3 |
| TMEM107 | RTN4IP1 | 0.71452 | 3 | 0 | 3 |
| TMEM107 | LRRC28 | 0.712666 | 3 | 0 | 3 |
| TMEM107 | NOTCH3 | 0.712079 | 3 | 0 | 3 |
| TMEM107 | PDPN | 0.708438 | 3 | 0 | 3 |
| TMEM107 | FBXO36 | 0.701127 | 3 | 0 | 3 |
| TMEM107 | TCTN2 | 0.699283 | 4 | 0 | 4 |
| TMEM107 | IMPDH2 | 0.698341 | 3 | 0 | 3 |
| TMEM107 | ZBED5 | 0.697284 | 3 | 0 | 3 |
| TMEM107 | SNF8 | 0.696955 | 3 | 0 | 3 |
| TMEM107 | MTSS1 | 0.692749 | 3 | 0 | 3 |
For details and further investigation, click here
