| Full name: ring finger and CHY zinc finger domain containing 1 | Alias Symbol: CHIMP|DKFZp586C1620|PRO1996|RNF199|ARNIP|PIRH2|ZCHY | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 25898 | HGNC ID: HGNC:17479 | Ensembl Gene: ENSG00000163743 | OMIM ID: 607680 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
RCHY1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04115 | p53 signaling pathway | |
| hsa05162 | Measles |
Expression of RCHY1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCHY1 | 25898 | 214281_s_at | 0.3056 | 0.3972 | |
| GSE20347 | RCHY1 | 25898 | 214281_s_at | -0.2104 | 0.1350 | |
| GSE23400 | RCHY1 | 25898 | 214281_s_at | 0.0752 | 0.2683 | |
| GSE26886 | RCHY1 | 25898 | 214281_s_at | -0.6291 | 0.0056 | |
| GSE29001 | RCHY1 | 25898 | 214281_s_at | -0.2964 | 0.4257 | |
| GSE38129 | RCHY1 | 25898 | 214281_s_at | -0.1530 | 0.2408 | |
| GSE45670 | RCHY1 | 25898 | 214281_s_at | -0.0860 | 0.5976 | |
| GSE53622 | RCHY1 | 25898 | 35158 | -0.6386 | 0.0000 | |
| GSE53624 | RCHY1 | 25898 | 28088 | -0.6696 | 0.0000 | |
| GSE63941 | RCHY1 | 25898 | 212749_s_at | 0.3015 | 0.4234 | |
| GSE77861 | RCHY1 | 25898 | 214281_s_at | -0.6285 | 0.0363 | |
| GSE97050 | RCHY1 | 25898 | A_33_P3263841 | -0.4214 | 0.1531 | |
| SRP007169 | RCHY1 | 25898 | RNAseq | -0.5279 | 0.1995 | |
| SRP008496 | RCHY1 | 25898 | RNAseq | -0.3343 | 0.2113 | |
| SRP064894 | RCHY1 | 25898 | RNAseq | -0.5388 | 0.0003 | |
| SRP133303 | RCHY1 | 25898 | RNAseq | 0.2031 | 0.3789 | |
| SRP159526 | RCHY1 | 25898 | RNAseq | -0.2221 | 0.4207 | |
| SRP193095 | RCHY1 | 25898 | RNAseq | -0.3781 | 0.0000 | |
| SRP219564 | RCHY1 | 25898 | RNAseq | -0.3564 | 0.1701 | |
| TCGA | RCHY1 | 25898 | RNAseq | -0.2335 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RCHY1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCHY1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCHY1 | 25898 | 2 | 9 | 19 | |
| GSE20123 | RCHY1 | 25898 | 2 | 9 | 19 | |
| GSE43470 | RCHY1 | 25898 | 0 | 13 | 30 | |
| GSE46452 | RCHY1 | 25898 | 2 | 35 | 22 | |
| GSE47630 | RCHY1 | 25898 | 1 | 19 | 20 | |
| GSE54993 | RCHY1 | 25898 | 7 | 0 | 63 | |
| GSE54994 | RCHY1 | 25898 | 1 | 9 | 43 | |
| GSE60625 | RCHY1 | 25898 | 0 | 0 | 11 | |
| GSE74703 | RCHY1 | 25898 | 0 | 11 | 25 | |
| GSE74704 | RCHY1 | 25898 | 2 | 5 | 13 | |
| TCGA | RCHY1 | 25898 | 17 | 30 | 49 |
Total number of gains: 34; Total number of losses: 140; Total Number of normals: 314.
Somatic mutations of RCHY1:
Generating mutation plots.
Highly correlated genes for RCHY1:
Showing top 20/636 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCHY1 | FNBP1L | 0.802976 | 3 | 0 | 3 |
| RCHY1 | TYW5 | 0.800035 | 3 | 0 | 3 |
| RCHY1 | EGLN1 | 0.796938 | 3 | 0 | 3 |
| RCHY1 | ATG3 | 0.771072 | 3 | 0 | 3 |
| RCHY1 | SNX4 | 0.766056 | 4 | 0 | 4 |
| RCHY1 | ZNF207 | 0.758984 | 3 | 0 | 3 |
| RCHY1 | MSL3 | 0.758666 | 3 | 0 | 3 |
| RCHY1 | EXOSC10 | 0.753783 | 3 | 0 | 3 |
| RCHY1 | RNPC3 | 0.75307 | 3 | 0 | 3 |
| RCHY1 | TMEM50A | 0.751669 | 3 | 0 | 3 |
| RCHY1 | TP53RK | 0.749893 | 4 | 0 | 4 |
| RCHY1 | MRPL1 | 0.741065 | 5 | 0 | 5 |
| RCHY1 | SPIC | 0.733697 | 3 | 0 | 3 |
| RCHY1 | PRKAR2A | 0.730349 | 3 | 0 | 3 |
| RCHY1 | CNOT6L | 0.728995 | 7 | 0 | 6 |
| RCHY1 | TSPAN5 | 0.726311 | 4 | 0 | 4 |
| RCHY1 | HSPA9 | 0.722512 | 3 | 0 | 3 |
| RCHY1 | LZIC | 0.720902 | 3 | 0 | 3 |
| RCHY1 | EIF3E | 0.716439 | 3 | 0 | 3 |
| RCHY1 | CRNKL1 | 0.714323 | 3 | 0 | 3 |
For details and further investigation, click here
