| Full name: N-myristoyltransferase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 9397 | HGNC ID: HGNC:7858 | Ensembl Gene: ENSG00000152465 | OMIM ID: 603801 |
| Drug and gene relationship at DGIdb | |||
Expression of NMT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMT2 | 9397 | 205005_s_at | -0.4352 | 0.5836 | |
| GSE20347 | NMT2 | 9397 | 205006_s_at | 0.0033 | 0.9892 | |
| GSE23400 | NMT2 | 9397 | 205006_s_at | 0.1381 | 0.0413 | |
| GSE26886 | NMT2 | 9397 | 205005_s_at | -0.2178 | 0.4295 | |
| GSE29001 | NMT2 | 9397 | 205006_s_at | 0.0205 | 0.9394 | |
| GSE38129 | NMT2 | 9397 | 205006_s_at | -0.2555 | 0.2719 | |
| GSE45670 | NMT2 | 9397 | 205005_s_at | -0.8169 | 0.0001 | |
| GSE53622 | NMT2 | 9397 | 4675 | -0.1131 | 0.2295 | |
| GSE53624 | NMT2 | 9397 | 4675 | 0.0282 | 0.8377 | |
| GSE63941 | NMT2 | 9397 | 205006_s_at | -1.5446 | 0.0857 | |
| GSE77861 | NMT2 | 9397 | 215069_at | -0.0492 | 0.6866 | |
| GSE97050 | NMT2 | 9397 | A_23_P138693 | 0.0181 | 0.9537 | |
| SRP007169 | NMT2 | 9397 | RNAseq | 0.9440 | 0.0751 | |
| SRP008496 | NMT2 | 9397 | RNAseq | 0.7883 | 0.0703 | |
| SRP064894 | NMT2 | 9397 | RNAseq | -0.1326 | 0.4218 | |
| SRP133303 | NMT2 | 9397 | RNAseq | -0.2631 | 0.0306 | |
| SRP159526 | NMT2 | 9397 | RNAseq | 0.0545 | 0.8445 | |
| SRP193095 | NMT2 | 9397 | RNAseq | -0.2327 | 0.0331 | |
| SRP219564 | NMT2 | 9397 | RNAseq | -0.2073 | 0.5431 | |
| TCGA | NMT2 | 9397 | RNAseq | -0.1149 | 0.1514 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NMT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NMT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMT2 | 9397 | 3 | 8 | 19 | |
| GSE20123 | NMT2 | 9397 | 3 | 7 | 20 | |
| GSE43470 | NMT2 | 9397 | 3 | 5 | 35 | |
| GSE46452 | NMT2 | 9397 | 1 | 14 | 44 | |
| GSE47630 | NMT2 | 9397 | 5 | 15 | 20 | |
| GSE54993 | NMT2 | 9397 | 10 | 0 | 60 | |
| GSE54994 | NMT2 | 9397 | 4 | 9 | 40 | |
| GSE60625 | NMT2 | 9397 | 0 | 0 | 11 | |
| GSE74703 | NMT2 | 9397 | 2 | 3 | 31 | |
| GSE74704 | NMT2 | 9397 | 0 | 6 | 14 | |
| TCGA | NMT2 | 9397 | 19 | 26 | 51 |
Total number of gains: 50; Total number of losses: 93; Total Number of normals: 345.
Somatic mutations of NMT2:
Generating mutation plots.
Highly correlated genes for NMT2:
Showing top 20/612 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMT2 | PPP2CB | 0.792745 | 3 | 0 | 3 |
| NMT2 | SPRY1 | 0.784299 | 3 | 0 | 3 |
| NMT2 | ZNF570 | 0.774972 | 3 | 0 | 3 |
| NMT2 | APOD | 0.727103 | 3 | 0 | 3 |
| NMT2 | ACO1 | 0.726338 | 4 | 0 | 4 |
| NMT2 | SLC46A3 | 0.724854 | 4 | 0 | 4 |
| NMT2 | ZNF441 | 0.722089 | 3 | 0 | 3 |
| NMT2 | S1PR1 | 0.721456 | 4 | 0 | 4 |
| NMT2 | USP16 | 0.720259 | 3 | 0 | 3 |
| NMT2 | IGFBP6 | 0.717888 | 4 | 0 | 4 |
| NMT2 | PTGIS | 0.716994 | 4 | 0 | 4 |
| NMT2 | TGM2 | 0.716628 | 4 | 0 | 4 |
| NMT2 | EMCN | 0.712541 | 3 | 0 | 3 |
| NMT2 | TXNIP | 0.7111 | 3 | 0 | 3 |
| NMT2 | ZMAT3 | 0.702062 | 3 | 0 | 3 |
| NMT2 | DIXDC1 | 0.701901 | 5 | 0 | 5 |
| NMT2 | AFF1 | 0.696443 | 3 | 0 | 3 |
| NMT2 | FLNB | 0.69595 | 3 | 0 | 3 |
| NMT2 | ZNF358 | 0.694696 | 3 | 0 | 3 |
| NMT2 | FBXO3 | 0.693097 | 3 | 0 | 3 |
For details and further investigation, click here
