| Full name: transmembrane protein 38A | Alias Symbol: MGC3169|TRIC-A | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 79041 | HGNC ID: HGNC:28462 | Ensembl Gene: ENSG00000072954 | OMIM ID: 611235 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM38A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM38A | 79041 | 222896_at | -0.2853 | 0.3529 | |
| GSE26886 | TMEM38A | 79041 | 222896_at | -0.1373 | 0.2603 | |
| GSE45670 | TMEM38A | 79041 | 222896_at | -0.0513 | 0.7804 | |
| GSE53622 | TMEM38A | 79041 | 40205 | -0.1018 | 0.1586 | |
| GSE53624 | TMEM38A | 79041 | 40205 | -0.0828 | 0.3065 | |
| GSE63941 | TMEM38A | 79041 | 222896_at | -0.0060 | 0.9900 | |
| GSE77861 | TMEM38A | 79041 | 222896_at | -0.4871 | 0.0025 | |
| GSE97050 | TMEM38A | 79041 | A_23_P101392 | -0.1906 | 0.4079 | |
| SRP064894 | TMEM38A | 79041 | RNAseq | -0.2386 | 0.5241 | |
| SRP133303 | TMEM38A | 79041 | RNAseq | -0.5366 | 0.0158 | |
| SRP193095 | TMEM38A | 79041 | RNAseq | -1.1681 | 0.0000 | |
| SRP219564 | TMEM38A | 79041 | RNAseq | 0.4569 | 0.4800 | |
| TCGA | TMEM38A | 79041 | RNAseq | -1.0197 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TMEM38A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM38A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM38A | 79041 | 4 | 3 | 23 | |
| GSE20123 | TMEM38A | 79041 | 3 | 2 | 25 | |
| GSE43470 | TMEM38A | 79041 | 2 | 6 | 35 | |
| GSE46452 | TMEM38A | 79041 | 47 | 1 | 11 | |
| GSE47630 | TMEM38A | 79041 | 4 | 8 | 28 | |
| GSE54993 | TMEM38A | 79041 | 15 | 4 | 51 | |
| GSE54994 | TMEM38A | 79041 | 6 | 14 | 33 | |
| GSE60625 | TMEM38A | 79041 | 9 | 0 | 2 | |
| GSE74703 | TMEM38A | 79041 | 2 | 4 | 30 | |
| GSE74704 | TMEM38A | 79041 | 0 | 1 | 19 | |
| TCGA | TMEM38A | 79041 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 52; Total Number of normals: 327.
Somatic mutations of TMEM38A:
Generating mutation plots.
Highly correlated genes for TMEM38A:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM38A | CCIN | 0.82503 | 3 | 0 | 3 |
| TMEM38A | CAPN3 | 0.789242 | 3 | 0 | 3 |
| TMEM38A | GUF1 | 0.778456 | 3 | 0 | 3 |
| TMEM38A | SREK1IP1 | 0.76961 | 3 | 0 | 3 |
| TMEM38A | PPP3CC | 0.759027 | 3 | 0 | 3 |
| TMEM38A | FBXW7 | 0.753483 | 3 | 0 | 3 |
| TMEM38A | NDUFA2 | 0.749212 | 3 | 0 | 3 |
| TMEM38A | MKNK2 | 0.748869 | 3 | 0 | 3 |
| TMEM38A | LPAR6 | 0.748469 | 3 | 0 | 3 |
| TMEM38A | MRPS36 | 0.748422 | 3 | 0 | 3 |
| TMEM38A | ZNF214 | 0.742692 | 3 | 0 | 3 |
| TMEM38A | OPTN | 0.742441 | 3 | 0 | 3 |
| TMEM38A | CCDC154 | 0.741095 | 3 | 0 | 3 |
| TMEM38A | XKR6 | 0.740811 | 3 | 0 | 3 |
| TMEM38A | TNP2 | 0.7378 | 3 | 0 | 3 |
| TMEM38A | THOC7 | 0.734337 | 3 | 0 | 3 |
| TMEM38A | TRNAU1AP | 0.731265 | 3 | 0 | 3 |
| TMEM38A | SPAG16 | 0.726008 | 3 | 0 | 3 |
| TMEM38A | JOSD2 | 0.719502 | 4 | 0 | 4 |
| TMEM38A | TDRD3 | 0.718425 | 3 | 0 | 3 |
For details and further investigation, click here
