| Full name: ankyrin repeat domain 12 | Alias Symbol: KIAA0874|FLJ20053|GAC-1 | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 23253 | HGNC ID: HGNC:29135 | Ensembl Gene: ENSG00000101745 | OMIM ID: 610616 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD12 | 23253 | 216550_x_at | -0.2900 | 0.7541 | |
| GSE20347 | ANKRD12 | 23253 | 212286_at | -0.4303 | 0.0473 | |
| GSE23400 | ANKRD12 | 23253 | 212286_at | -0.2586 | 0.0034 | |
| GSE26886 | ANKRD12 | 23253 | 212286_at | -0.6207 | 0.0028 | |
| GSE29001 | ANKRD12 | 23253 | 212286_at | -0.4020 | 0.1440 | |
| GSE38129 | ANKRD12 | 23253 | 216550_x_at | -0.2934 | 0.0713 | |
| GSE45670 | ANKRD12 | 23253 | 216550_x_at | -0.1067 | 0.4908 | |
| GSE53622 | ANKRD12 | 23253 | 37403 | -0.6630 | 0.0000 | |
| GSE53624 | ANKRD12 | 23253 | 37403 | -0.6193 | 0.0000 | |
| GSE63941 | ANKRD12 | 23253 | 212286_at | -0.9665 | 0.3282 | |
| GSE77861 | ANKRD12 | 23253 | 212286_at | -0.2012 | 0.6709 | |
| GSE97050 | ANKRD12 | 23253 | A_33_P3294524 | -0.7547 | 0.0786 | |
| SRP007169 | ANKRD12 | 23253 | RNAseq | -0.3348 | 0.4286 | |
| SRP008496 | ANKRD12 | 23253 | RNAseq | -0.1998 | 0.4618 | |
| SRP064894 | ANKRD12 | 23253 | RNAseq | -0.3901 | 0.1027 | |
| SRP133303 | ANKRD12 | 23253 | RNAseq | -0.3761 | 0.0088 | |
| SRP159526 | ANKRD12 | 23253 | RNAseq | -0.4781 | 0.1123 | |
| SRP193095 | ANKRD12 | 23253 | RNAseq | -0.6133 | 0.0000 | |
| SRP219564 | ANKRD12 | 23253 | RNAseq | -0.7338 | 0.0622 | |
| TCGA | ANKRD12 | 23253 | RNAseq | -0.2638 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD12 | 23253 | 6 | 3 | 21 | |
| GSE20123 | ANKRD12 | 23253 | 6 | 3 | 21 | |
| GSE43470 | ANKRD12 | 23253 | 3 | 6 | 34 | |
| GSE46452 | ANKRD12 | 23253 | 3 | 21 | 35 | |
| GSE47630 | ANKRD12 | 23253 | 7 | 17 | 16 | |
| GSE54993 | ANKRD12 | 23253 | 6 | 3 | 61 | |
| GSE54994 | ANKRD12 | 23253 | 9 | 8 | 36 | |
| GSE60625 | ANKRD12 | 23253 | 0 | 4 | 7 | |
| GSE74703 | ANKRD12 | 23253 | 2 | 4 | 30 | |
| GSE74704 | ANKRD12 | 23253 | 4 | 2 | 14 | |
| TCGA | ANKRD12 | 23253 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 94; Total Number of normals: 319.
Somatic mutations of ANKRD12:
Generating mutation plots.
Highly correlated genes for ANKRD12:
Showing top 20/601 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD12 | NPHP3 | 0.775037 | 3 | 0 | 3 |
| ANKRD12 | C5orf51 | 0.758297 | 3 | 0 | 3 |
| ANKRD12 | PPIG | 0.746852 | 4 | 0 | 4 |
| ANKRD12 | ANGPTL1 | 0.731005 | 3 | 0 | 3 |
| ANKRD12 | KCTD21 | 0.715689 | 3 | 0 | 3 |
| ANKRD12 | ZBTB16 | 0.702593 | 4 | 0 | 4 |
| ANKRD12 | ANKHD1 | 0.700059 | 4 | 0 | 4 |
| ANKRD12 | P2RX1 | 0.697583 | 3 | 0 | 3 |
| ANKRD12 | FAM122C | 0.6965 | 3 | 0 | 3 |
| ANKRD12 | AKAP8L | 0.694548 | 3 | 0 | 3 |
| ANKRD12 | CDX1 | 0.690491 | 3 | 0 | 3 |
| ANKRD12 | MIER3 | 0.689629 | 3 | 0 | 3 |
| ANKRD12 | ZNF585A | 0.689336 | 4 | 0 | 4 |
| ANKRD12 | SRSF8 | 0.68904 | 3 | 0 | 3 |
| ANKRD12 | NKTR | 0.687945 | 4 | 0 | 3 |
| ANKRD12 | TBCA | 0.686132 | 4 | 0 | 3 |
| ANKRD12 | FYTTD1 | 0.685788 | 3 | 0 | 3 |
| ANKRD12 | ZNF638 | 0.685332 | 4 | 0 | 3 |
| ANKRD12 | XKR4 | 0.683733 | 3 | 0 | 3 |
| ANKRD12 | SREK1IP1 | 0.679568 | 4 | 0 | 3 |
For details and further investigation, click here
