| Full name: tsukushi, small leucine rich proteoglycan | Alias Symbol: E2IG4|TSK | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 25987 | HGNC ID: HGNC:28850 | Ensembl Gene: ENSG00000182704 | OMIM ID: 608015 |
| Drug and gene relationship at DGIdb | |||
Expression of TSKU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSKU | 25987 | 218245_at | 0.1054 | 0.8939 | |
| GSE20347 | TSKU | 25987 | 218245_at | -0.0237 | 0.9011 | |
| GSE23400 | TSKU | 25987 | 218245_at | 0.1719 | 0.0297 | |
| GSE26886 | TSKU | 25987 | 218245_at | 0.3730 | 0.0030 | |
| GSE29001 | TSKU | 25987 | 218245_at | -0.2999 | 0.0590 | |
| GSE38129 | TSKU | 25987 | 218245_at | 0.1339 | 0.5262 | |
| GSE45670 | TSKU | 25987 | 218245_at | 0.2532 | 0.1219 | |
| GSE53622 | TSKU | 25987 | 37138 | 0.3211 | 0.0136 | |
| GSE53624 | TSKU | 25987 | 37138 | 0.1972 | 0.0423 | |
| GSE63941 | TSKU | 25987 | 218245_at | 0.3502 | 0.5854 | |
| GSE77861 | TSKU | 25987 | 218245_at | 0.1758 | 0.5041 | |
| GSE97050 | TSKU | 25987 | A_23_P162142 | 0.2945 | 0.5313 | |
| SRP007169 | TSKU | 25987 | RNAseq | -0.9829 | 0.0250 | |
| SRP008496 | TSKU | 25987 | RNAseq | -0.7758 | 0.0011 | |
| SRP064894 | TSKU | 25987 | RNAseq | 0.0979 | 0.7088 | |
| SRP133303 | TSKU | 25987 | RNAseq | -0.1502 | 0.2750 | |
| SRP159526 | TSKU | 25987 | RNAseq | 0.0040 | 0.9931 | |
| SRP193095 | TSKU | 25987 | RNAseq | 0.0872 | 0.5451 | |
| SRP219564 | TSKU | 25987 | RNAseq | 0.3313 | 0.6114 | |
| TCGA | TSKU | 25987 | RNAseq | 0.2406 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSKU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSKU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSKU | 25987 | 5 | 9 | 16 | |
| GSE20123 | TSKU | 25987 | 5 | 8 | 17 | |
| GSE43470 | TSKU | 25987 | 3 | 3 | 37 | |
| GSE46452 | TSKU | 25987 | 7 | 22 | 30 | |
| GSE47630 | TSKU | 25987 | 5 | 16 | 19 | |
| GSE54993 | TSKU | 25987 | 8 | 2 | 60 | |
| GSE54994 | TSKU | 25987 | 6 | 17 | 30 | |
| GSE60625 | TSKU | 25987 | 4 | 3 | 4 | |
| GSE74703 | TSKU | 25987 | 2 | 2 | 32 | |
| GSE74704 | TSKU | 25987 | 3 | 4 | 13 | |
| TCGA | TSKU | 25987 | 20 | 31 | 45 |
Total number of gains: 68; Total number of losses: 117; Total Number of normals: 303.
Somatic mutations of TSKU:
Generating mutation plots.
Highly correlated genes for TSKU:
Showing top 20/152 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSKU | PTRHD1 | 0.671407 | 3 | 0 | 3 |
| TSKU | CLNS1A | 0.640246 | 10 | 0 | 8 |
| TSKU | FAM110A | 0.639221 | 3 | 0 | 3 |
| TSKU | MAP7 | 0.632377 | 3 | 0 | 3 |
| TSKU | TMEM33 | 0.622665 | 4 | 0 | 3 |
| TSKU | GFI1 | 0.620969 | 3 | 0 | 3 |
| TSKU | ZNF385C | 0.611355 | 3 | 0 | 3 |
| TSKU | ZDHHC12 | 0.609534 | 5 | 0 | 5 |
| TSKU | PRR13 | 0.609145 | 3 | 0 | 3 |
| TSKU | RGS20 | 0.604269 | 7 | 0 | 5 |
| TSKU | ZNF552 | 0.596466 | 4 | 0 | 3 |
| TSKU | CORO1B | 0.588363 | 3 | 0 | 3 |
| TSKU | RAB38 | 0.587196 | 9 | 0 | 7 |
| TSKU | JUNB | 0.586418 | 3 | 0 | 3 |
| TSKU | FAM83H | 0.585597 | 5 | 0 | 3 |
| TSKU | RAB32 | 0.585071 | 3 | 0 | 3 |
| TSKU | WNT10A | 0.582478 | 5 | 0 | 3 |
| TSKU | TMEM126B | 0.582333 | 3 | 0 | 3 |
| TSKU | FAM83B | 0.582186 | 5 | 0 | 3 |
| TSKU | ST14 | 0.580126 | 4 | 0 | 3 |
For details and further investigation, click here
