| Full name: transmembrane protein 126B | Alias Symbol: HT007 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 55863 | HGNC ID: HGNC:30883 | Ensembl Gene: ENSG00000171204 | OMIM ID: 615533 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMEM126B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM126B | 55863 | 221622_s_at | -0.0985 | 0.7395 | |
| GSE20347 | TMEM126B | 55863 | 221622_s_at | 0.1560 | 0.5062 | |
| GSE23400 | TMEM126B | 55863 | 221622_s_at | 0.2901 | 0.0033 | |
| GSE26886 | TMEM126B | 55863 | 221622_s_at | -0.3243 | 0.1605 | |
| GSE29001 | TMEM126B | 55863 | 221622_s_at | 0.0672 | 0.8549 | |
| GSE38129 | TMEM126B | 55863 | 221622_s_at | 0.0761 | 0.6316 | |
| GSE45670 | TMEM126B | 55863 | 221622_s_at | 0.1330 | 0.4862 | |
| GSE53622 | TMEM126B | 55863 | 3585 | 0.1054 | 0.1900 | |
| GSE53624 | TMEM126B | 55863 | 3585 | 0.1181 | 0.2496 | |
| GSE63941 | TMEM126B | 55863 | 221622_s_at | -0.0512 | 0.9068 | |
| GSE77861 | TMEM126B | 55863 | 221622_s_at | -0.2254 | 0.5973 | |
| GSE97050 | TMEM126B | 55863 | A_23_P2129 | 0.3735 | 0.3168 | |
| SRP007169 | TMEM126B | 55863 | RNAseq | 0.0455 | 0.9145 | |
| SRP008496 | TMEM126B | 55863 | RNAseq | -0.0349 | 0.8842 | |
| SRP064894 | TMEM126B | 55863 | RNAseq | 0.2930 | 0.1236 | |
| SRP133303 | TMEM126B | 55863 | RNAseq | 0.1398 | 0.3538 | |
| SRP159526 | TMEM126B | 55863 | RNAseq | -0.5521 | 0.0879 | |
| SRP193095 | TMEM126B | 55863 | RNAseq | -0.4103 | 0.0070 | |
| SRP219564 | TMEM126B | 55863 | RNAseq | -0.2239 | 0.3783 | |
| TCGA | TMEM126B | 55863 | RNAseq | -0.0920 | 0.1329 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM126B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM126B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM126B | 55863 | 4 | 9 | 17 | |
| GSE20123 | TMEM126B | 55863 | 4 | 9 | 17 | |
| GSE43470 | TMEM126B | 55863 | 3 | 4 | 36 | |
| GSE46452 | TMEM126B | 55863 | 6 | 24 | 29 | |
| GSE47630 | TMEM126B | 55863 | 2 | 19 | 19 | |
| GSE54993 | TMEM126B | 55863 | 8 | 2 | 60 | |
| GSE54994 | TMEM126B | 55863 | 5 | 19 | 29 | |
| GSE60625 | TMEM126B | 55863 | 0 | 3 | 8 | |
| GSE74703 | TMEM126B | 55863 | 2 | 3 | 31 | |
| GSE74704 | TMEM126B | 55863 | 3 | 6 | 11 | |
| TCGA | TMEM126B | 55863 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 136; Total Number of normals: 299.
Somatic mutations of TMEM126B:
Generating mutation plots.
Highly correlated genes for TMEM126B:
Showing top 20/382 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM126B | ZNF354C | 0.756228 | 3 | 0 | 3 |
| TMEM126B | GLOD4 | 0.753861 | 3 | 0 | 3 |
| TMEM126B | CHUK | 0.739595 | 3 | 0 | 3 |
| TMEM126B | EMB | 0.732858 | 3 | 0 | 3 |
| TMEM126B | RTF1 | 0.729808 | 3 | 0 | 3 |
| TMEM126B | CDC123 | 0.728863 | 4 | 0 | 4 |
| TMEM126B | FAU | 0.724422 | 4 | 0 | 3 |
| TMEM126B | PPIL1 | 0.7176 | 3 | 0 | 3 |
| TMEM126B | TMEM126A | 0.715025 | 9 | 0 | 9 |
| TMEM126B | RGS18 | 0.714952 | 3 | 0 | 3 |
| TMEM126B | PSMD7 | 0.712015 | 3 | 0 | 3 |
| TMEM126B | CDC40 | 0.705802 | 4 | 0 | 4 |
| TMEM126B | EED | 0.70105 | 12 | 0 | 10 |
| TMEM126B | EIF2S1 | 0.699339 | 4 | 0 | 4 |
| TMEM126B | SAAL1 | 0.698601 | 3 | 0 | 3 |
| TMEM126B | TAF11 | 0.697021 | 3 | 0 | 3 |
| TMEM126B | ARL16 | 0.696707 | 3 | 0 | 3 |
| TMEM126B | CRK | 0.690224 | 4 | 0 | 3 |
| TMEM126B | NUDT15 | 0.689322 | 3 | 0 | 3 |
| TMEM126B | STT3B | 0.68837 | 3 | 0 | 3 |
For details and further investigation, click here
