| Full name: peptidyl-tRNA hydrolase domain containing 1 | Alias Symbol: LOC391356 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 391356 | HGNC ID: HGNC:33782 | Ensembl Gene: ENSG00000184924 | OMIM ID: 617342 |
| Drug and gene relationship at DGIdb | |||
Expression of PTRHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTRHD1 | 391356 | 226243_at | -0.0004 | 0.9991 | |
| GSE26886 | PTRHD1 | 391356 | 226243_at | 0.6700 | 0.0000 | |
| GSE45670 | PTRHD1 | 391356 | 226243_at | -0.2783 | 0.0142 | |
| GSE53622 | PTRHD1 | 391356 | 31459 | -0.3197 | 0.0007 | |
| GSE53624 | PTRHD1 | 391356 | 31459 | -0.3960 | 0.0000 | |
| GSE63941 | PTRHD1 | 391356 | 226243_at | 0.3528 | 0.4168 | |
| GSE77861 | PTRHD1 | 391356 | 226243_at | -0.4963 | 0.0036 | |
| GSE97050 | PTRHD1 | 391356 | A_24_P16036 | 0.1497 | 0.5939 | |
| SRP007169 | PTRHD1 | 391356 | RNAseq | -1.2924 | 0.0012 | |
| SRP008496 | PTRHD1 | 391356 | RNAseq | -1.0586 | 0.0000 | |
| SRP064894 | PTRHD1 | 391356 | RNAseq | 0.0872 | 0.7796 | |
| SRP133303 | PTRHD1 | 391356 | RNAseq | -0.4826 | 0.0105 | |
| SRP159526 | PTRHD1 | 391356 | RNAseq | -0.2717 | 0.3121 | |
| SRP193095 | PTRHD1 | 391356 | RNAseq | -0.7420 | 0.0000 | |
| SRP219564 | PTRHD1 | 391356 | RNAseq | 0.2338 | 0.6254 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PTRHD1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PTRHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTRHD1 | 391356 | 11 | 2 | 17 | |
| GSE20123 | PTRHD1 | 391356 | 11 | 2 | 17 | |
| GSE43470 | PTRHD1 | 391356 | 2 | 1 | 40 | |
| GSE46452 | PTRHD1 | 391356 | 3 | 4 | 52 | |
| GSE47630 | PTRHD1 | 391356 | 8 | 0 | 32 | |
| GSE54993 | PTRHD1 | 391356 | 0 | 6 | 64 | |
| GSE54994 | PTRHD1 | 391356 | 10 | 0 | 43 | |
| GSE60625 | PTRHD1 | 391356 | 0 | 3 | 8 | |
| GSE74703 | PTRHD1 | 391356 | 2 | 0 | 34 | |
| GSE74704 | PTRHD1 | 391356 | 9 | 1 | 10 | |
| TCGA | PTRHD1 | 391356 | 36 | 3 | 57 |
Total number of gains: 92; Total number of losses: 22; Total Number of normals: 374.
Somatic mutations of PTRHD1:
Generating mutation plots.
Highly correlated genes for PTRHD1:
Showing top 20/236 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTRHD1 | ROMO1 | 0.8056 | 3 | 0 | 3 |
| PTRHD1 | GMCL1 | 0.752308 | 3 | 0 | 3 |
| PTRHD1 | NCKAP1 | 0.72349 | 3 | 0 | 3 |
| PTRHD1 | ARIH1 | 0.708018 | 3 | 0 | 3 |
| PTRHD1 | ETFA | 0.706841 | 3 | 0 | 3 |
| PTRHD1 | LCMT1 | 0.706222 | 3 | 0 | 3 |
| PTRHD1 | RPL34 | 0.705117 | 4 | 0 | 4 |
| PTRHD1 | COMMD3 | 0.694734 | 4 | 0 | 3 |
| PTRHD1 | NECAP2 | 0.690583 | 4 | 0 | 4 |
| PTRHD1 | MARVELD2 | 0.68761 | 3 | 0 | 3 |
| PTRHD1 | PPA1 | 0.687124 | 4 | 0 | 3 |
| PTRHD1 | PRKAR2A | 0.685672 | 4 | 0 | 3 |
| PTRHD1 | TSTD1 | 0.684439 | 6 | 0 | 5 |
| PTRHD1 | ARHGEF5 | 0.681071 | 3 | 0 | 3 |
| PTRHD1 | TSPAN31 | 0.679279 | 3 | 0 | 3 |
| PTRHD1 | HIVEP1 | 0.676072 | 3 | 0 | 3 |
| PTRHD1 | PGLS | 0.675816 | 4 | 0 | 3 |
| PTRHD1 | CNKSR1 | 0.67531 | 4 | 0 | 3 |
| PTRHD1 | NRXN2 | 0.673802 | 3 | 0 | 3 |
| PTRHD1 | CYFIP1 | 0.673251 | 5 | 0 | 5 |
For details and further investigation, click here
