| Full name: suppression of tumorigenicity 14 | Alias Symbol: SNC19|HAI|MT-SP1|TMPRSS14 | ||
| Type: protein-coding gene | Cytoband: 11q24.3 | ||
| Entrez ID: 6768 | HGNC ID: HGNC:11344 | Ensembl Gene: ENSG00000149418 | OMIM ID: 606797 |
| Drug and gene relationship at DGIdb | |||
Expression of ST14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST14 | 6768 | 202005_at | 0.6032 | 0.4087 | |
| GSE20347 | ST14 | 6768 | 202005_at | -0.4193 | 0.0102 | |
| GSE23400 | ST14 | 6768 | 202005_at | -0.3758 | 0.0001 | |
| GSE26886 | ST14 | 6768 | 202005_at | -0.3753 | 0.0632 | |
| GSE29001 | ST14 | 6768 | 202005_at | -0.5685 | 0.0724 | |
| GSE38129 | ST14 | 6768 | 202005_at | -0.0277 | 0.9225 | |
| GSE45670 | ST14 | 6768 | 202005_at | 0.2293 | 0.2020 | |
| GSE53622 | ST14 | 6768 | 25255 | -0.1016 | 0.6520 | |
| GSE53624 | ST14 | 6768 | 25255 | -0.5573 | 0.0000 | |
| GSE63941 | ST14 | 6768 | 202005_at | 2.4275 | 0.0007 | |
| GSE77861 | ST14 | 6768 | 202005_at | -0.1499 | 0.3788 | |
| GSE97050 | ST14 | 6768 | A_23_P47282 | 0.7394 | 0.4070 | |
| SRP007169 | ST14 | 6768 | RNAseq | -1.5062 | 0.0006 | |
| SRP008496 | ST14 | 6768 | RNAseq | -0.9878 | 0.0011 | |
| SRP064894 | ST14 | 6768 | RNAseq | -0.8654 | 0.0006 | |
| SRP133303 | ST14 | 6768 | RNAseq | -0.5757 | 0.0146 | |
| SRP159526 | ST14 | 6768 | RNAseq | -1.1650 | 0.0000 | |
| SRP193095 | ST14 | 6768 | RNAseq | -0.7482 | 0.0000 | |
| SRP219564 | ST14 | 6768 | RNAseq | -0.9931 | 0.2654 | |
| TCGA | ST14 | 6768 | RNAseq | 0.1900 | 0.0460 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ST14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST14 | 6768 | 0 | 13 | 17 | |
| GSE20123 | ST14 | 6768 | 0 | 13 | 17 | |
| GSE43470 | ST14 | 6768 | 2 | 7 | 34 | |
| GSE46452 | ST14 | 6768 | 3 | 26 | 30 | |
| GSE47630 | ST14 | 6768 | 2 | 19 | 19 | |
| GSE54993 | ST14 | 6768 | 10 | 0 | 60 | |
| GSE54994 | ST14 | 6768 | 5 | 19 | 29 | |
| GSE60625 | ST14 | 6768 | 0 | 3 | 8 | |
| GSE74703 | ST14 | 6768 | 1 | 5 | 30 | |
| GSE74704 | ST14 | 6768 | 0 | 9 | 11 | |
| TCGA | ST14 | 6768 | 5 | 50 | 41 |
Total number of gains: 28; Total number of losses: 164; Total Number of normals: 296.
Somatic mutations of ST14:
Generating mutation plots.
Highly correlated genes for ST14:
Showing top 20/488 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST14 | GRHL2 | 0.756025 | 6 | 0 | 5 |
| ST14 | TSEN54 | 0.717923 | 4 | 0 | 4 |
| ST14 | FXYD3 | 0.714834 | 5 | 0 | 4 |
| ST14 | JRK | 0.707966 | 3 | 0 | 3 |
| ST14 | F11R | 0.687377 | 7 | 0 | 6 |
| ST14 | MARVELD2 | 0.680382 | 6 | 0 | 5 |
| ST14 | TRIM29 | 0.678724 | 12 | 0 | 11 |
| ST14 | CITED4 | 0.67537 | 4 | 0 | 3 |
| ST14 | ALPK1 | 0.674515 | 3 | 0 | 3 |
| ST14 | ARRDC1 | 0.673003 | 7 | 0 | 5 |
| ST14 | SPINT2 | 0.670825 | 10 | 0 | 8 |
| ST14 | FAM83H | 0.670246 | 7 | 0 | 5 |
| ST14 | TMC6 | 0.669586 | 6 | 0 | 5 |
| ST14 | PRKCZ | 0.668973 | 8 | 0 | 7 |
| ST14 | MAP7 | 0.668099 | 7 | 0 | 6 |
| ST14 | MAL2 | 0.665459 | 7 | 0 | 5 |
| ST14 | RCC2 | 0.664763 | 4 | 0 | 3 |
| ST14 | SFN | 0.659893 | 7 | 0 | 6 |
| ST14 | HOOK1 | 0.651699 | 9 | 0 | 7 |
| ST14 | KIAA1522 | 0.650814 | 5 | 0 | 4 |
For details and further investigation, click here
