| Full name: RAB38, member RAS oncogene family | Alias Symbol: NY-MEL-1 | ||
| Type: protein-coding gene | Cytoband: 11q14.2 | ||
| Entrez ID: 23682 | HGNC ID: HGNC:9776 | Ensembl Gene: ENSG00000123892 | OMIM ID: 606281 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB38 | 23682 | 219412_at | -0.1089 | 0.9431 | |
| GSE20347 | RAB38 | 23682 | 219412_at | -0.7158 | 0.0381 | |
| GSE23400 | RAB38 | 23682 | 219412_at | 0.0206 | 0.9127 | |
| GSE26886 | RAB38 | 23682 | 219412_at | -0.4409 | 0.1402 | |
| GSE29001 | RAB38 | 23682 | 219412_at | -0.6321 | 0.1838 | |
| GSE38129 | RAB38 | 23682 | 219412_at | 0.1924 | 0.7099 | |
| GSE45670 | RAB38 | 23682 | 219412_at | 0.5981 | 0.0047 | |
| GSE53622 | RAB38 | 23682 | 89633 | 0.3892 | 0.0963 | |
| GSE53624 | RAB38 | 23682 | 89633 | -0.4231 | 0.0093 | |
| GSE63941 | RAB38 | 23682 | 219412_at | 1.9209 | 0.1820 | |
| GSE77861 | RAB38 | 23682 | 219412_at | -0.3417 | 0.5135 | |
| GSE97050 | RAB38 | 23682 | A_23_P161563 | 1.3705 | 0.1834 | |
| SRP007169 | RAB38 | 23682 | RNAseq | -0.8296 | 0.1118 | |
| SRP008496 | RAB38 | 23682 | RNAseq | -0.9345 | 0.0101 | |
| SRP064894 | RAB38 | 23682 | RNAseq | -0.2166 | 0.5564 | |
| SRP133303 | RAB38 | 23682 | RNAseq | 0.0626 | 0.8341 | |
| SRP159526 | RAB38 | 23682 | RNAseq | -0.9199 | 0.1224 | |
| SRP193095 | RAB38 | 23682 | RNAseq | -0.5526 | 0.1164 | |
| SRP219564 | RAB38 | 23682 | RNAseq | -0.2187 | 0.8137 | |
| TCGA | RAB38 | 23682 | RNAseq | 1.1123 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RAB38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB38 | 23682 | 3 | 10 | 17 | |
| GSE20123 | RAB38 | 23682 | 3 | 10 | 17 | |
| GSE43470 | RAB38 | 23682 | 3 | 4 | 36 | |
| GSE46452 | RAB38 | 23682 | 6 | 23 | 30 | |
| GSE47630 | RAB38 | 23682 | 2 | 19 | 19 | |
| GSE54993 | RAB38 | 23682 | 8 | 2 | 60 | |
| GSE54994 | RAB38 | 23682 | 5 | 19 | 29 | |
| GSE60625 | RAB38 | 23682 | 0 | 4 | 7 | |
| GSE74703 | RAB38 | 23682 | 2 | 3 | 31 | |
| GSE74704 | RAB38 | 23682 | 3 | 6 | 11 | |
| TCGA | RAB38 | 23682 | 15 | 39 | 42 |
Total number of gains: 50; Total number of losses: 139; Total Number of normals: 299.
Somatic mutations of RAB38:
Generating mutation plots.
Highly correlated genes for RAB38:
Showing top 20/609 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB38 | SLC25A43 | 0.731461 | 4 | 0 | 4 |
| RAB38 | ZNRD1 | 0.72295 | 3 | 0 | 3 |
| RAB38 | SERINC2 | 0.714453 | 4 | 0 | 4 |
| RAB38 | ATP11B | 0.711066 | 4 | 0 | 4 |
| RAB38 | LIMK2 | 0.702408 | 9 | 0 | 9 |
| RAB38 | FAM83A | 0.700988 | 7 | 0 | 7 |
| RAB38 | PSPH | 0.69726 | 3 | 0 | 3 |
| RAB38 | HM13 | 0.682209 | 4 | 0 | 4 |
| RAB38 | JARID2 | 0.680249 | 4 | 0 | 3 |
| RAB38 | FAM83B | 0.679923 | 8 | 0 | 6 |
| RAB38 | DSG3 | 0.678432 | 12 | 0 | 11 |
| RAB38 | S100A2 | 0.674971 | 12 | 0 | 10 |
| RAB38 | SLC37A2 | 0.668578 | 4 | 0 | 3 |
| RAB38 | GSR | 0.66795 | 4 | 0 | 3 |
| RAB38 | CERS3 | 0.667357 | 6 | 0 | 5 |
| RAB38 | XIAP | 0.66715 | 5 | 0 | 4 |
| RAB38 | KRT6B | 0.665674 | 12 | 0 | 12 |
| RAB38 | SPIN4 | 0.665408 | 3 | 0 | 3 |
| RAB38 | HMGA1 | 0.662426 | 5 | 0 | 4 |
| RAB38 | ELOVL1 | 0.660458 | 4 | 0 | 3 |
For details and further investigation, click here
