| Full name: proline rich 13 | Alias Symbol: FLJ23818|DKFZP564J157 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 54458 | HGNC ID: HGNC:24528 | Ensembl Gene: ENSG00000205352 | OMIM ID: 610459 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRR13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR13 | 54458 | 217794_at | 0.1514 | 0.6433 | |
| GSE20347 | PRR13 | 54458 | 217794_at | 0.1181 | 0.2468 | |
| GSE23400 | PRR13 | 54458 | 217794_at | 0.1131 | 0.0389 | |
| GSE26886 | PRR13 | 54458 | 217794_at | -0.2066 | 0.1210 | |
| GSE29001 | PRR13 | 54458 | 217794_at | -0.0861 | 0.6123 | |
| GSE38129 | PRR13 | 54458 | 217794_at | 0.1516 | 0.1051 | |
| GSE45670 | PRR13 | 54458 | 217794_at | 0.1379 | 0.1841 | |
| GSE53622 | PRR13 | 54458 | 102408 | -0.1741 | 0.0037 | |
| GSE53624 | PRR13 | 54458 | 102408 | 0.0297 | 0.5237 | |
| GSE63941 | PRR13 | 54458 | 217794_at | -0.1791 | 0.6654 | |
| GSE77861 | PRR13 | 54458 | 217794_at | 0.1684 | 0.3164 | |
| GSE97050 | PRR13 | 54458 | A_24_P349466 | 0.2795 | 0.3194 | |
| SRP007169 | PRR13 | 54458 | RNAseq | -1.2362 | 0.0004 | |
| SRP008496 | PRR13 | 54458 | RNAseq | -1.0990 | 0.0000 | |
| SRP064894 | PRR13 | 54458 | RNAseq | -0.1501 | 0.3904 | |
| SRP133303 | PRR13 | 54458 | RNAseq | 0.1485 | 0.3337 | |
| SRP159526 | PRR13 | 54458 | RNAseq | -0.4205 | 0.0692 | |
| SRP193095 | PRR13 | 54458 | RNAseq | -0.5979 | 0.0022 | |
| SRP219564 | PRR13 | 54458 | RNAseq | 0.1333 | 0.6381 | |
| TCGA | PRR13 | 54458 | RNAseq | -0.2000 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRR13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR13 | 54458 | 7 | 1 | 22 | |
| GSE20123 | PRR13 | 54458 | 7 | 1 | 22 | |
| GSE43470 | PRR13 | 54458 | 3 | 0 | 40 | |
| GSE46452 | PRR13 | 54458 | 7 | 1 | 51 | |
| GSE47630 | PRR13 | 54458 | 10 | 2 | 28 | |
| GSE54993 | PRR13 | 54458 | 0 | 5 | 65 | |
| GSE54994 | PRR13 | 54458 | 4 | 1 | 48 | |
| GSE60625 | PRR13 | 54458 | 0 | 0 | 11 | |
| GSE74703 | PRR13 | 54458 | 3 | 0 | 33 | |
| GSE74704 | PRR13 | 54458 | 5 | 1 | 14 | |
| TCGA | PRR13 | 54458 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of PRR13:
Generating mutation plots.
Highly correlated genes for PRR13:
Showing top 20/253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR13 | MAN2B1 | 0.77499 | 3 | 0 | 3 |
| PRR13 | KEAP1 | 0.756617 | 3 | 0 | 3 |
| PRR13 | SSBP4 | 0.755902 | 3 | 0 | 3 |
| PRR13 | SMARCD2 | 0.748699 | 4 | 0 | 3 |
| PRR13 | RNF213 | 0.721573 | 4 | 0 | 4 |
| PRR13 | RFX1 | 0.715544 | 3 | 0 | 3 |
| PRR13 | MIA3 | 0.715017 | 3 | 0 | 3 |
| PRR13 | HCLS1 | 0.706722 | 4 | 0 | 4 |
| PRR13 | PTGES | 0.704701 | 3 | 0 | 3 |
| PRR13 | SLC39A7 | 0.703499 | 3 | 0 | 3 |
| PRR13 | EHMT2 | 0.701961 | 3 | 0 | 3 |
| PRR13 | STAT5A | 0.696125 | 3 | 0 | 3 |
| PRR13 | OS9 | 0.695673 | 5 | 0 | 4 |
| PRR13 | L3MBTL3 | 0.695112 | 3 | 0 | 3 |
| PRR13 | TRMT2A | 0.68595 | 3 | 0 | 3 |
| PRR13 | GORAB | 0.685699 | 3 | 0 | 3 |
| PRR13 | BROX | 0.685157 | 3 | 0 | 3 |
| PRR13 | GPR160 | 0.684268 | 4 | 0 | 3 |
| PRR13 | MRPL51 | 0.678324 | 3 | 0 | 3 |
| PRR13 | VMA21 | 0.677679 | 3 | 0 | 3 |
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