TSPAN32

 

Full name: tetraspanin 32 Alias Symbol: 
Type: protein-coding gene Cytoband: 11p15.5
Entrez ID: 10077 HGNC ID: HGNC:13410 Ensembl Gene: ENSG00000064201 OMIM ID: 603853
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of TSPAN32:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TSPAN32 10077 220558_x_at -0.0681 0.8243
GSE20347 TSPAN32 10077 220558_x_at -0.1484 0.1107
GSE23400 TSPAN32 10077 220558_x_at -0.0997 0.0048
GSE26886 TSPAN32 10077 220558_x_at 0.1889 0.2287
GSE29001 TSPAN32 10077 220558_x_at -0.2660 0.1297
GSE38129 TSPAN32 10077 220558_x_at -0.3151 0.0002
GSE45670 TSPAN32 10077 220558_x_at -0.0908 0.3612
GSE53622 TSPAN32 10077 117429 -0.1411 0.1282
GSE53624 TSPAN32 10077 117429 -0.0266 0.7554
GSE63941 TSPAN32 10077 220558_x_at 0.4318 0.0053
GSE77861 TSPAN32 10077 233467_s_at -0.1201 0.2655
GSE97050 TSPAN32 10077 A_33_P3394404 0.1204 0.6537
SRP064894 TSPAN32 10077 RNAseq -0.3485 0.3522
SRP133303 TSPAN32 10077 RNAseq -0.5789 0.0012
SRP159526 TSPAN32 10077 RNAseq -0.7830 0.1625
SRP219564 TSPAN32 10077 RNAseq -0.1852 0.7311
TCGA TSPAN32 10077 RNAseq -0.9494 0.0026

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TSPAN32 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TSPAN32:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TSPAN32 10077 1 11 18
GSE20123 TSPAN32 10077 1 12 17
GSE43470 TSPAN32 10077 1 9 33
GSE46452 TSPAN32 10077 7 8 44
GSE47630 TSPAN32 10077 4 12 24
GSE54993 TSPAN32 10077 3 1 66
GSE54994 TSPAN32 10077 1 12 40
GSE60625 TSPAN32 10077 0 0 11
GSE74703 TSPAN32 10077 1 7 28
GSE74704 TSPAN32 10077 0 8 12
TCGA TSPAN32 10077 8 39 49

Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.  


 

Somatic mutations of TSPAN32:

 

Generating mutation plots.

 

Highly correlated genes for TSPAN32:

 

Showing top 20/929 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TSPAN32TMEM1790.787524303
TSPAN32ODF3B0.748075404
TSPAN32CHTF80.746834303
TSPAN32MAGEA80.745983303
TSPAN32CCDC1140.741746303
TSPAN32RGL40.740687404
TSPAN32VCX20.732377403
TSPAN32LRRC450.723838303
TSPAN32THRSP0.720841303
TSPAN32SLC22A310.718695404
TSPAN32MUC80.715575606
TSPAN32SLC35F30.704386303
TSPAN32PRODH20.704276807
TSPAN32TPRN0.703811303
TSPAN32PTK2B0.701923303
TSPAN32TBX40.700856504
TSPAN32FAM71A0.699199303
TSPAN32WDR380.697841303
TSPAN32PRAM10.69439303
TSPAN32MYO1A0.693887606

For details and further investigation, click here