| Full name: ral guanine nucleotide dissociation stimulator like 4 | Alias Symbol: Rgr | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 266747 | HGNC ID: HGNC:31911 | Ensembl Gene: ENSG00000159496 | OMIM ID: 612214 |
| Drug and gene relationship at DGIdb | |||
Expression of RGL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGL4 | 266747 | 235816_s_at | -0.1068 | 0.6706 | |
| GSE26886 | RGL4 | 266747 | 235816_s_at | -0.1291 | 0.4030 | |
| GSE45670 | RGL4 | 266747 | 235816_s_at | -0.0399 | 0.7903 | |
| GSE53622 | RGL4 | 266747 | 35922 | -0.2069 | 0.0037 | |
| GSE53624 | RGL4 | 266747 | 35922 | -0.5230 | 0.0000 | |
| GSE63941 | RGL4 | 266747 | 235816_s_at | -0.1284 | 0.4562 | |
| GSE77861 | RGL4 | 266747 | 235816_s_at | -0.1819 | 0.1239 | |
| GSE97050 | RGL4 | 266747 | A_23_P306941 | 0.1433 | 0.5340 | |
| SRP064894 | RGL4 | 266747 | RNAseq | 0.1944 | 0.4937 | |
| SRP133303 | RGL4 | 266747 | RNAseq | -0.1343 | 0.3574 | |
| SRP159526 | RGL4 | 266747 | RNAseq | -0.1379 | 0.6802 | |
| SRP193095 | RGL4 | 266747 | RNAseq | 0.0967 | 0.4461 | |
| SRP219564 | RGL4 | 266747 | RNAseq | 0.3693 | 0.3667 | |
| TCGA | RGL4 | 266747 | RNAseq | -0.7961 | 0.0046 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RGL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGL4 | 266747 | 5 | 7 | 18 | |
| GSE20123 | RGL4 | 266747 | 5 | 6 | 19 | |
| GSE43470 | RGL4 | 266747 | 3 | 6 | 34 | |
| GSE46452 | RGL4 | 266747 | 32 | 1 | 26 | |
| GSE47630 | RGL4 | 266747 | 8 | 5 | 27 | |
| GSE54993 | RGL4 | 266747 | 3 | 6 | 61 | |
| GSE54994 | RGL4 | 266747 | 11 | 7 | 35 | |
| GSE60625 | RGL4 | 266747 | 5 | 0 | 6 | |
| GSE74703 | RGL4 | 266747 | 3 | 5 | 28 | |
| GSE74704 | RGL4 | 266747 | 2 | 3 | 15 | |
| TCGA | RGL4 | 266747 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of RGL4:
Generating mutation plots.
Highly correlated genes for RGL4:
Showing top 20/186 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGL4 | PGLYRP1 | 0.821139 | 3 | 0 | 3 |
| RGL4 | MYO1A | 0.809823 | 3 | 0 | 3 |
| RGL4 | C20orf173 | 0.80657 | 3 | 0 | 3 |
| RGL4 | MAGEL2 | 0.775763 | 3 | 0 | 3 |
| RGL4 | CD300LG | 0.771402 | 4 | 0 | 4 |
| RGL4 | PKLR | 0.754817 | 3 | 0 | 3 |
| RGL4 | CELF4 | 0.753464 | 3 | 0 | 3 |
| RGL4 | TERT | 0.752657 | 3 | 0 | 3 |
| RGL4 | FAM110B | 0.749978 | 3 | 0 | 3 |
| RGL4 | ZGLP1 | 0.748211 | 4 | 0 | 4 |
| RGL4 | COX4I2 | 0.744981 | 3 | 0 | 3 |
| RGL4 | LSMEM2 | 0.743795 | 3 | 0 | 3 |
| RGL4 | TSPAN32 | 0.740687 | 4 | 0 | 4 |
| RGL4 | ANKFN1 | 0.737754 | 3 | 0 | 3 |
| RGL4 | UROC1 | 0.737109 | 3 | 0 | 3 |
| RGL4 | C11orf21 | 0.732177 | 3 | 0 | 3 |
| RGL4 | CTSE | 0.726247 | 4 | 0 | 4 |
| RGL4 | CCL25 | 0.72588 | 3 | 0 | 3 |
| RGL4 | IGSF21 | 0.72403 | 3 | 0 | 3 |
| RGL4 | PNPLA5 | 0.718031 | 3 | 0 | 3 |
For details and further investigation, click here
