| Full name: taperin | Alias Symbol: FLJ90254 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 286262 | HGNC ID: HGNC:26894 | Ensembl Gene: ENSG00000176058 | OMIM ID: 613354 |
| Drug and gene relationship at DGIdb | |||
Expression of TPRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPRN | 286262 | 225891_at | -0.4389 | 0.3487 | |
| GSE26886 | TPRN | 286262 | 225891_at | -0.0990 | 0.6307 | |
| GSE45670 | TPRN | 286262 | 225891_at | -0.3978 | 0.0204 | |
| GSE53622 | TPRN | 286262 | 136688 | -1.1084 | 0.0000 | |
| GSE53624 | TPRN | 286262 | 136688 | -0.9396 | 0.0000 | |
| GSE63941 | TPRN | 286262 | 225891_at | 0.7021 | 0.0525 | |
| GSE77861 | TPRN | 286262 | 225891_at | -0.3775 | 0.0164 | |
| GSE97050 | TPRN | 286262 | A_33_P3297923 | -0.0547 | 0.8963 | |
| SRP007169 | TPRN | 286262 | RNAseq | -2.4497 | 0.0000 | |
| SRP008496 | TPRN | 286262 | RNAseq | -2.4261 | 0.0000 | |
| SRP064894 | TPRN | 286262 | RNAseq | -0.7861 | 0.0303 | |
| SRP133303 | TPRN | 286262 | RNAseq | -1.3166 | 0.0000 | |
| SRP159526 | TPRN | 286262 | RNAseq | -0.9351 | 0.0022 | |
| SRP193095 | TPRN | 286262 | RNAseq | -1.0714 | 0.0000 | |
| SRP219564 | TPRN | 286262 | RNAseq | -0.9332 | 0.1118 | |
| TCGA | TPRN | 286262 | RNAseq | -0.3194 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by TPRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPRN | 286262 | 5 | 7 | 18 | |
| GSE20123 | TPRN | 286262 | 5 | 7 | 18 | |
| GSE43470 | TPRN | 286262 | 3 | 7 | 33 | |
| GSE46452 | TPRN | 286262 | 6 | 13 | 40 | |
| GSE47630 | TPRN | 286262 | 6 | 15 | 19 | |
| GSE54993 | TPRN | 286262 | 3 | 3 | 64 | |
| GSE54994 | TPRN | 286262 | 12 | 8 | 33 | |
| GSE60625 | TPRN | 286262 | 0 | 0 | 11 | |
| GSE74703 | TPRN | 286262 | 3 | 5 | 28 | |
| GSE74704 | TPRN | 286262 | 3 | 5 | 12 | |
| TCGA | TPRN | 286262 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of TPRN:
Generating mutation plots.
Highly correlated genes for TPRN:
Showing top 20/944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPRN | SMAGP | 0.800628 | 6 | 0 | 6 |
| TPRN | EPS8L2 | 0.784 | 6 | 0 | 6 |
| TPRN | ACPP | 0.779525 | 5 | 0 | 5 |
| TPRN | MGST2 | 0.779257 | 5 | 0 | 5 |
| TPRN | NCCRP1 | 0.773561 | 3 | 0 | 3 |
| TPRN | ESPL1 | 0.770618 | 6 | 0 | 6 |
| TPRN | TTC22 | 0.769462 | 6 | 0 | 6 |
| TPRN | ERBB2 | 0.765902 | 6 | 0 | 6 |
| TPRN | NHP2 | 0.765803 | 3 | 0 | 3 |
| TPRN | PGAP3 | 0.760892 | 6 | 0 | 6 |
| TPRN | CHP1 | 0.760184 | 5 | 0 | 5 |
| TPRN | GBP6 | 0.756587 | 3 | 0 | 3 |
| TPRN | LIPH | 0.756515 | 6 | 0 | 6 |
| TPRN | SCNN1B | 0.752924 | 6 | 0 | 6 |
| TPRN | PPFIBP2 | 0.751921 | 4 | 0 | 4 |
| TPRN | TTC9 | 0.750293 | 5 | 0 | 5 |
| TPRN | DEGS2 | 0.744208 | 6 | 0 | 6 |
| TPRN | NCR1 | 0.742693 | 3 | 0 | 3 |
| TPRN | ACOT8 | 0.739 | 4 | 0 | 4 |
| TPRN | TMEM141 | 0.737574 | 5 | 0 | 5 |
For details and further investigation, click here
