| Full name: chromosome transmission fidelity factor 8 | Alias Symbol: FLJ20400|CTF8 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 54921 | HGNC ID: HGNC:24353 | Ensembl Gene: ENSG00000168802 | OMIM ID: 613202 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CHTF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHTF8 | 54921 | 224732_at | 0.0135 | 0.9779 | |
| GSE26886 | CHTF8 | 54921 | 224732_at | -0.8147 | 0.0000 | |
| GSE45670 | CHTF8 | 54921 | 224732_at | 0.3272 | 0.0001 | |
| GSE53622 | CHTF8 | 54921 | 45385 | -0.1910 | 0.0001 | |
| GSE53624 | CHTF8 | 54921 | 45385 | -0.1218 | 0.1503 | |
| GSE63941 | CHTF8 | 54921 | 224732_at | 0.9176 | 0.0192 | |
| GSE77861 | CHTF8 | 54921 | 224732_at | 0.0743 | 0.6236 | |
| GSE97050 | CHTF8 | A_21_P0013760 | 0.0199 | 0.9387 | ||
| SRP007169 | CHTF8 | 54921 | RNAseq | -0.5698 | 0.1410 | |
| SRP064894 | CHTF8 | 54921 | RNAseq | -0.0873 | 0.5881 | |
| SRP133303 | CHTF8 | 54921 | RNAseq | -0.0101 | 0.9613 | |
| SRP159526 | CHTF8 | 54921 | RNAseq | -0.1396 | 0.6981 | |
| SRP193095 | CHTF8 | 54921 | RNAseq | -0.3740 | 0.0111 | |
| SRP219564 | CHTF8 | 54921 | RNAseq | 0.8586 | 0.2224 | |
| TCGA | CHTF8 | 54921 | RNAseq | -0.0288 | 0.5100 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CHTF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHTF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHTF8 | 54921 | 8 | 1 | 21 | |
| GSE20123 | CHTF8 | 54921 | 8 | 1 | 21 | |
| GSE43470 | CHTF8 | 54921 | 2 | 8 | 33 | |
| GSE46452 | CHTF8 | 54921 | 38 | 1 | 20 | |
| GSE47630 | CHTF8 | 54921 | 11 | 8 | 21 | |
| GSE54993 | CHTF8 | 54921 | 2 | 4 | 64 | |
| GSE54994 | CHTF8 | 54921 | 8 | 10 | 35 | |
| GSE60625 | CHTF8 | 54921 | 4 | 0 | 7 | |
| GSE74703 | CHTF8 | 54921 | 2 | 5 | 29 | |
| GSE74704 | CHTF8 | 54921 | 4 | 0 | 16 | |
| TCGA | CHTF8 | 54921 | 29 | 13 | 54 |
Total number of gains: 116; Total number of losses: 51; Total Number of normals: 321.
Somatic mutations of CHTF8:
Generating mutation plots.
Highly correlated genes for CHTF8:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHTF8 | TSPAN32 | 0.746834 | 3 | 0 | 3 |
| CHTF8 | CDCA5 | 0.743243 | 3 | 0 | 3 |
| CHTF8 | MEI1 | 0.732015 | 4 | 0 | 4 |
| CHTF8 | MAPKAPK3 | 0.729542 | 3 | 0 | 3 |
| CHTF8 | CNTD2 | 0.727571 | 3 | 0 | 3 |
| CHTF8 | WAS | 0.725313 | 3 | 0 | 3 |
| CHTF8 | AICDA | 0.71966 | 3 | 0 | 3 |
| CHTF8 | RIPK4 | 0.715711 | 3 | 0 | 3 |
| CHTF8 | PRODH2 | 0.713848 | 3 | 0 | 3 |
| CHTF8 | SLC35C1 | 0.712467 | 3 | 0 | 3 |
| CHTF8 | CNGB3 | 0.700707 | 3 | 0 | 3 |
| CHTF8 | CEP19 | 0.694605 | 3 | 0 | 3 |
| CHTF8 | EPHA1 | 0.687801 | 3 | 0 | 3 |
| CHTF8 | CLEC4D | 0.686381 | 3 | 0 | 3 |
| CHTF8 | FAM124B | 0.686051 | 3 | 0 | 3 |
| CHTF8 | BRICD5 | 0.685199 | 3 | 0 | 3 |
| CHTF8 | TGM5 | 0.684076 | 3 | 0 | 3 |
| CHTF8 | ZNF519 | 0.683513 | 3 | 0 | 3 |
| CHTF8 | OIP5 | 0.679528 | 3 | 0 | 3 |
| CHTF8 | CACNG4 | 0.678786 | 3 | 0 | 3 |
For details and further investigation, click here
