| Full name: DLG associated protein 4 | Alias Symbol: DAP4|KIAA0964|SAPAP4 | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 22839 | HGNC ID: HGNC:24476 | Ensembl Gene: ENSG00000080845 | OMIM ID: 616191 |
| Drug and gene relationship at DGIdb | |||
Expression of DLGAP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLGAP4 | 22839 | 233056_x_at | 0.2423 | 0.7709 | |
| GSE20347 | DLGAP4 | 22839 | 202570_s_at | 0.3190 | 0.0604 | |
| GSE23400 | DLGAP4 | 22839 | 202572_s_at | 0.2629 | 0.0014 | |
| GSE26886 | DLGAP4 | 22839 | 233056_x_at | 0.2110 | 0.3929 | |
| GSE29001 | DLGAP4 | 22839 | 202570_s_at | 0.6718 | 0.0120 | |
| GSE38129 | DLGAP4 | 22839 | 202570_s_at | 0.2524 | 0.1838 | |
| GSE45670 | DLGAP4 | 22839 | 233056_x_at | 0.2653 | 0.0349 | |
| GSE53622 | DLGAP4 | 22839 | 36038 | 0.6586 | 0.0000 | |
| GSE53624 | DLGAP4 | 22839 | 36038 | 0.5369 | 0.0000 | |
| GSE63941 | DLGAP4 | 22839 | 233056_x_at | -0.2015 | 0.2490 | |
| GSE77861 | DLGAP4 | 22839 | 233056_x_at | 0.2638 | 0.4967 | |
| GSE97050 | DLGAP4 | 22839 | A_24_P216253 | 0.4091 | 0.2946 | |
| SRP007169 | DLGAP4 | 22839 | RNAseq | 0.2179 | 0.6869 | |
| SRP008496 | DLGAP4 | 22839 | RNAseq | 0.1570 | 0.6342 | |
| SRP064894 | DLGAP4 | 22839 | RNAseq | 0.7272 | 0.0001 | |
| SRP133303 | DLGAP4 | 22839 | RNAseq | 0.5416 | 0.0003 | |
| SRP159526 | DLGAP4 | 22839 | RNAseq | 0.7325 | 0.0751 | |
| SRP193095 | DLGAP4 | 22839 | RNAseq | 0.6088 | 0.0000 | |
| SRP219564 | DLGAP4 | 22839 | RNAseq | 0.3139 | 0.4362 | |
| TCGA | DLGAP4 | 22839 | RNAseq | 0.0637 | 0.1733 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DLGAP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLGAP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLGAP4 | 22839 | 14 | 2 | 14 | |
| GSE20123 | DLGAP4 | 22839 | 14 | 2 | 14 | |
| GSE43470 | DLGAP4 | 22839 | 12 | 0 | 31 | |
| GSE46452 | DLGAP4 | 22839 | 29 | 0 | 30 | |
| GSE47630 | DLGAP4 | 22839 | 24 | 0 | 16 | |
| GSE54993 | DLGAP4 | 22839 | 0 | 17 | 53 | |
| GSE54994 | DLGAP4 | 22839 | 24 | 0 | 29 | |
| GSE60625 | DLGAP4 | 22839 | 0 | 0 | 11 | |
| GSE74703 | DLGAP4 | 22839 | 11 | 0 | 25 | |
| GSE74704 | DLGAP4 | 22839 | 10 | 1 | 9 | |
| TCGA | DLGAP4 | 22839 | 49 | 3 | 44 |
Total number of gains: 187; Total number of losses: 25; Total Number of normals: 276.
Somatic mutations of DLGAP4:
Generating mutation plots.
Highly correlated genes for DLGAP4:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLGAP4 | CMBL | 0.855367 | 5 | 0 | 5 |
| DLGAP4 | DDX59 | 0.849112 | 5 | 0 | 5 |
| DLGAP4 | UBXN2A | 0.823497 | 5 | 0 | 5 |
| DLGAP4 | FAM161B | 0.815862 | 6 | 0 | 6 |
| DLGAP4 | UACA | 0.79158 | 4 | 0 | 4 |
| DLGAP4 | FUT8-AS1 | 0.790342 | 4 | 0 | 4 |
| DLGAP4 | C9orf64 | 0.785304 | 7 | 0 | 6 |
| DLGAP4 | CWC22 | 0.780226 | 3 | 0 | 3 |
| DLGAP4 | RAB2B | 0.780179 | 3 | 0 | 3 |
| DLGAP4 | TNRC6C-AS1 | 0.763649 | 5 | 0 | 5 |
| DLGAP4 | EIF3C | 0.763369 | 3 | 0 | 3 |
| DLGAP4 | SSBP3-AS1 | 0.745573 | 5 | 0 | 5 |
| DLGAP4 | NLN | 0.743283 | 7 | 0 | 5 |
| DLGAP4 | NAA15 | 0.738233 | 3 | 0 | 3 |
| DLGAP4 | KIAA1143 | 0.734465 | 3 | 0 | 3 |
| DLGAP4 | SRP19 | 0.73338 | 3 | 0 | 3 |
| DLGAP4 | NEK8 | 0.721602 | 4 | 0 | 3 |
| DLGAP4 | CYCS | 0.712973 | 3 | 0 | 3 |
| DLGAP4 | RABEP1 | 0.712744 | 3 | 0 | 3 |
| DLGAP4 | OCIAD1 | 0.707798 | 4 | 0 | 3 |
For details and further investigation, click here
