| Full name: peroxisomal trans-2-enoyl-CoA reductase | Alias Symbol: HSA250303|TERP|SDR29C1 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 55825 | HGNC ID: HGNC:18281 | Ensembl Gene: ENSG00000115425 | OMIM ID: 605843 |
| Drug and gene relationship at DGIdb | |||
Expression of PECR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PECR | 55825 | 223619_x_at | -0.0133 | 0.9870 | |
| GSE20347 | PECR | 55825 | 221142_s_at | 0.0845 | 0.3516 | |
| GSE23400 | PECR | 55825 | 221142_s_at | -0.1119 | 0.0244 | |
| GSE26886 | PECR | 55825 | 223619_x_at | 0.2348 | 0.2458 | |
| GSE29001 | PECR | 55825 | 221142_s_at | 0.1247 | 0.4759 | |
| GSE38129 | PECR | 55825 | 221142_s_at | -0.0199 | 0.9020 | |
| GSE45670 | PECR | 55825 | 223619_x_at | 0.1650 | 0.1557 | |
| GSE53622 | PECR | 55825 | 42461 | -0.5584 | 0.0222 | |
| GSE53624 | PECR | 55825 | 42461 | -1.1286 | 0.0000 | |
| GSE63941 | PECR | 55825 | 223619_x_at | 0.0600 | 0.7952 | |
| GSE77861 | PECR | 55825 | 223619_x_at | 0.2250 | 0.2797 | |
| GSE97050 | PECR | 55825 | A_23_P91140 | 0.1096 | 0.6781 | |
| SRP007169 | PECR | 55825 | RNAseq | 0.5134 | 0.2955 | |
| SRP008496 | PECR | 55825 | RNAseq | 0.7646 | 0.0476 | |
| SRP064894 | PECR | 55825 | RNAseq | 0.1178 | 0.5385 | |
| SRP133303 | PECR | 55825 | RNAseq | 0.0143 | 0.9083 | |
| SRP159526 | PECR | 55825 | RNAseq | 0.2611 | 0.4993 | |
| SRP193095 | PECR | 55825 | RNAseq | -0.3888 | 0.0570 | |
| SRP219564 | PECR | 55825 | RNAseq | -0.0288 | 0.9510 | |
| TCGA | PECR | 55825 | RNAseq | -0.2504 | 0.0608 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PECR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PECR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PECR | 55825 | 1 | 13 | 16 | |
| GSE20123 | PECR | 55825 | 1 | 13 | 16 | |
| GSE43470 | PECR | 55825 | 0 | 7 | 36 | |
| GSE46452 | PECR | 55825 | 0 | 5 | 54 | |
| GSE47630 | PECR | 55825 | 4 | 5 | 31 | |
| GSE54993 | PECR | 55825 | 0 | 3 | 67 | |
| GSE54994 | PECR | 55825 | 8 | 9 | 36 | |
| GSE60625 | PECR | 55825 | 0 | 3 | 8 | |
| GSE74703 | PECR | 55825 | 0 | 6 | 30 | |
| GSE74704 | PECR | 55825 | 1 | 7 | 12 | |
| TCGA | PECR | 55825 | 11 | 28 | 57 |
Total number of gains: 26; Total number of losses: 99; Total Number of normals: 363.
Somatic mutations of PECR:
Generating mutation plots.
Highly correlated genes for PECR:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PECR | UACA | 0.78383 | 3 | 0 | 3 |
| PECR | UBXN2A | 0.777446 | 5 | 0 | 5 |
| PECR | DDX59 | 0.771183 | 5 | 0 | 5 |
| PECR | CMBL | 0.770884 | 5 | 0 | 5 |
| PECR | FUT8-AS1 | 0.73397 | 4 | 0 | 4 |
| PECR | TNRC6C-AS1 | 0.725669 | 5 | 0 | 5 |
| PECR | SSBP3-AS1 | 0.720033 | 4 | 0 | 3 |
| PECR | FAM161B | 0.713975 | 5 | 0 | 4 |
| PECR | SNRNP200 | 0.703352 | 3 | 0 | 3 |
| PECR | RAMP2-AS1 | 0.694691 | 4 | 0 | 4 |
| PECR | SLC22A3 | 0.689925 | 6 | 0 | 5 |
| PECR | TRMT10B | 0.685415 | 5 | 0 | 5 |
| PECR | MRPL50 | 0.674135 | 3 | 0 | 3 |
| PECR | OCLM | 0.665129 | 3 | 0 | 3 |
| PECR | FKBP10 | 0.653977 | 3 | 0 | 3 |
| PECR | TCF7 | 0.647092 | 5 | 0 | 5 |
| PECR | TREX2 | 0.641537 | 3 | 0 | 3 |
| PECR | SMIM2 | 0.63362 | 3 | 0 | 3 |
| PECR | BIRC7 | 0.630554 | 3 | 0 | 3 |
| PECR | ZNF75A | 0.623666 | 4 | 0 | 3 |
For details and further investigation, click here
