UTF1

 

Full name: undifferentiated embryonic cell transcription factor 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 10q26.3
Entrez ID: 8433 HGNC ID: HGNC:12634 Ensembl Gene: ENSG00000171794 OMIM ID: 604130
Drug and gene relationship at DGIdb

 

Expression of UTF1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UTF1 8433 208275_x_at 0.0168 0.9458
GSE20347 UTF1 8433 208275_x_at -0.1722 0.0040
GSE23400 UTF1 8433 208275_x_at -0.1592 0.0000
GSE26886 UTF1 8433 208275_x_at 0.0686 0.5263
GSE29001 UTF1 8433 208275_x_at -0.2343 0.1079
GSE38129 UTF1 8433 208275_x_at -0.2730 0.0000
GSE45670 UTF1 8433 208275_x_at 0.0202 0.8407
GSE53622 UTF1 8433 87061 -0.2810 0.0024
GSE53624 UTF1 8433 87061 -0.6832 0.0000
GSE63941 UTF1 8433 208275_x_at -0.0858 0.5015
GSE77861 UTF1 8433 208275_x_at -0.1118 0.2788
GSE97050 UTF1 8433 A_33_P3294217 0.0277 0.9341
TCGA UTF1 8433 RNAseq 1.2697 0.2447

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by UTF1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UTF1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UTF1 8433 3 8 19
GSE20123 UTF1 8433 3 9 18
GSE43470 UTF1 8433 0 9 34
GSE46452 UTF1 8433 1 11 47
GSE47630 UTF1 8433 4 13 23
GSE54993 UTF1 8433 8 2 60
GSE54994 UTF1 8433 1 9 43
GSE60625 UTF1 8433 0 0 11
GSE74703 UTF1 8433 0 6 30
GSE74704 UTF1 8433 3 4 13
TCGA UTF1 8433 7 28 61

Total number of gains: 30; Total number of losses: 99; Total Number of normals: 359.  


 

Somatic mutations of UTF1:

 

Generating mutation plots.

 

Highly correlated genes for UTF1:

 

Showing top 20/636 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UTF1KIR3DL20.819309303
UTF1RIMBP20.76338303
UTF1KRTAP9-60.749309303
UTF1MTTP0.739835303
UTF1TESPA10.732299303
UTF1KRTAP10-10.731273303
UTF1SLC45A20.728658303
UTF1ASCL10.718074303
UTF1TMEM63B0.713699303
UTF1SFTPA20.70782303
UTF1KRTAP19-20.699225303
UTF1CCNB30.697006303
UTF1PYHIN10.696631303
UTF1IFNA210.694854303
UTF1SERINC20.693394404
UTF1ZNF4160.693109303
UTF1NPY5R0.690544303
UTF1SAMD4B0.686605303
UTF1ZMAT40.685085404
UTF1OCM20.684954404

For details and further investigation, click here