| Full name: neuropeptide Y receptor Y5 | Alias Symbol: NPYR5 | ||
| Type: protein-coding gene | Cytoband: 4q32.2 | ||
| Entrez ID: 4889 | HGNC ID: HGNC:7958 | Ensembl Gene: ENSG00000164129 | OMIM ID: 602001 |
| Drug and gene relationship at DGIdb | |||
Expression of NPY5R:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPY5R | 4889 | 207400_at | -0.1064 | 0.7634 | |
| GSE20347 | NPY5R | 4889 | 207400_at | 0.0006 | 0.9946 | |
| GSE23400 | NPY5R | 4889 | 207400_at | -0.1210 | 0.0058 | |
| GSE26886 | NPY5R | 4889 | 207400_at | -0.0126 | 0.9205 | |
| GSE29001 | NPY5R | 4889 | 207400_at | -0.0793 | 0.7465 | |
| GSE38129 | NPY5R | 4889 | 207400_at | -0.1800 | 0.0249 | |
| GSE45670 | NPY5R | 4889 | 207400_at | -0.2385 | 0.0206 | |
| GSE53622 | NPY5R | 4889 | 45298 | -0.7237 | 0.0000 | |
| GSE53624 | NPY5R | 4889 | 45298 | -1.1852 | 0.0000 | |
| GSE63941 | NPY5R | 4889 | 207400_at | -0.5286 | 0.0003 | |
| GSE77861 | NPY5R | 4889 | 207400_at | -0.1210 | 0.1874 | |
| TCGA | NPY5R | 4889 | RNAseq | -2.0022 | 0.0608 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NPY5R expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPY5R:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPY5R | 4889 | 0 | 11 | 19 | |
| GSE20123 | NPY5R | 4889 | 0 | 11 | 19 | |
| GSE43470 | NPY5R | 4889 | 0 | 14 | 29 | |
| GSE46452 | NPY5R | 4889 | 1 | 36 | 22 | |
| GSE47630 | NPY5R | 4889 | 0 | 22 | 18 | |
| GSE54993 | NPY5R | 4889 | 10 | 0 | 60 | |
| GSE54994 | NPY5R | 4889 | 1 | 12 | 40 | |
| GSE60625 | NPY5R | 4889 | 0 | 0 | 11 | |
| GSE74703 | NPY5R | 4889 | 0 | 12 | 24 | |
| GSE74704 | NPY5R | 4889 | 0 | 5 | 15 | |
| TCGA | NPY5R | 4889 | 10 | 35 | 51 |
Total number of gains: 22; Total number of losses: 158; Total Number of normals: 308.
Somatic mutations of NPY5R:
Generating mutation plots.
Highly correlated genes for NPY5R:
Showing top 20/605 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPY5R | SLC5A4 | 0.72328 | 3 | 0 | 3 |
| NPY5R | NEUROD2 | 0.717162 | 3 | 0 | 3 |
| NPY5R | UGT2A3 | 0.695074 | 3 | 0 | 3 |
| NPY5R | UTF1 | 0.690544 | 3 | 0 | 3 |
| NPY5R | CYP2A7 | 0.689408 | 4 | 0 | 3 |
| NPY5R | ZMAT4 | 0.686493 | 5 | 0 | 5 |
| NPY5R | GK2 | 0.681349 | 3 | 0 | 3 |
| NPY5R | MATN1 | 0.675864 | 4 | 0 | 4 |
| NPY5R | CIDEC | 0.675838 | 4 | 0 | 4 |
| NPY5R | SHCBP1L | 0.673674 | 3 | 0 | 3 |
| NPY5R | SAG | 0.672067 | 3 | 0 | 3 |
| NPY5R | HHLA1 | 0.670531 | 4 | 0 | 4 |
| NPY5R | CCR9 | 0.666946 | 3 | 0 | 3 |
| NPY5R | NEU3 | 0.666383 | 4 | 0 | 4 |
| NPY5R | NMNAT2 | 0.6662 | 6 | 0 | 5 |
| NPY5R | USH1C | 0.666196 | 4 | 0 | 3 |
| NPY5R | IFNA4 | 0.663273 | 4 | 0 | 3 |
| NPY5R | GABRR2 | 0.661172 | 3 | 0 | 3 |
| NPY5R | PSG7 | 0.661044 | 4 | 0 | 3 |
| NPY5R | NGB | 0.660605 | 3 | 0 | 3 |
For details and further investigation, click here
