| Full name: microsomal triglyceride transfer protein | Alias Symbol: ABL | ||
| Type: protein-coding gene | Cytoband: 4q23 | ||
| Entrez ID: 4547 | HGNC ID: HGNC:7467 | Ensembl Gene: ENSG00000138823 | OMIM ID: 157147 |
| Drug and gene relationship at DGIdb | |||
Expression of MTTP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTTP | 4547 | 205675_at | 0.0041 | 0.9917 | |
| GSE20347 | MTTP | 4547 | 205675_at | 0.0047 | 0.9378 | |
| GSE23400 | MTTP | 4547 | 205675_at | -0.0451 | 0.0606 | |
| GSE26886 | MTTP | 4547 | 205675_at | 0.2027 | 0.0714 | |
| GSE29001 | MTTP | 4547 | 205675_at | -0.1319 | 0.2961 | |
| GSE38129 | MTTP | 4547 | 205675_at | -0.0253 | 0.8353 | |
| GSE45670 | MTTP | 4547 | 205675_at | -0.0052 | 0.9506 | |
| GSE53622 | MTTP | 4547 | 10742 | -0.3295 | 0.1267 | |
| GSE53624 | MTTP | 4547 | 10742 | -0.4658 | 0.0039 | |
| GSE63941 | MTTP | 4547 | 205675_at | 0.0695 | 0.6753 | |
| GSE77861 | MTTP | 4547 | 205675_at | -0.0030 | 0.9773 | |
| TCGA | MTTP | 4547 | RNAseq | -0.6692 | 0.2640 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTTP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTTP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTTP | 4547 | 0 | 12 | 18 | |
| GSE20123 | MTTP | 4547 | 0 | 12 | 18 | |
| GSE43470 | MTTP | 4547 | 0 | 13 | 30 | |
| GSE46452 | MTTP | 4547 | 1 | 36 | 22 | |
| GSE47630 | MTTP | 4547 | 0 | 20 | 20 | |
| GSE54993 | MTTP | 4547 | 9 | 0 | 61 | |
| GSE54994 | MTTP | 4547 | 1 | 11 | 41 | |
| GSE60625 | MTTP | 4547 | 0 | 3 | 8 | |
| GSE74703 | MTTP | 4547 | 0 | 11 | 25 | |
| GSE74704 | MTTP | 4547 | 0 | 6 | 14 | |
| TCGA | MTTP | 4547 | 8 | 40 | 48 |
Total number of gains: 19; Total number of losses: 164; Total Number of normals: 305.
Somatic mutations of MTTP:
Generating mutation plots.
Highly correlated genes for MTTP:
Showing top 20/304 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTTP | GCM1 | 0.740915 | 3 | 0 | 3 |
| MTTP | UTF1 | 0.739835 | 3 | 0 | 3 |
| MTTP | ASCL1 | 0.738521 | 4 | 0 | 4 |
| MTTP | OR2H2 | 0.729182 | 3 | 0 | 3 |
| MTTP | FAM153A | 0.725925 | 3 | 0 | 3 |
| MTTP | SLC17A4 | 0.714695 | 3 | 0 | 3 |
| MTTP | GJA8 | 0.713325 | 3 | 0 | 3 |
| MTTP | C11orf16 | 0.712604 | 3 | 0 | 3 |
| MTTP | CHGA | 0.70528 | 4 | 0 | 4 |
| MTTP | AMHR2 | 0.704155 | 3 | 0 | 3 |
| MTTP | TULP2 | 0.703348 | 3 | 0 | 3 |
| MTTP | ARPP21 | 0.699472 | 3 | 0 | 3 |
| MTTP | IFNA14 | 0.696716 | 3 | 0 | 3 |
| MTTP | KIR2DS1 | 0.694091 | 3 | 0 | 3 |
| MTTP | NNAT | 0.692233 | 3 | 0 | 3 |
| MTTP | SCGN | 0.68667 | 4 | 0 | 4 |
| MTTP | FBP2 | 0.685275 | 3 | 0 | 3 |
| MTTP | PEX5L | 0.684677 | 3 | 0 | 3 |
| MTTP | P2RY4 | 0.684028 | 3 | 0 | 3 |
| MTTP | PHEX | 0.683251 | 3 | 0 | 3 |
For details and further investigation, click here
