| Full name: myelin expression factor 2 | Alias Symbol: MEF-2|FLJ11213|KIAA1341|HsT18564 | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 50804 | HGNC ID: HGNC:17940 | Ensembl Gene: ENSG00000104177 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MYEF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYEF2 | 50804 | 232676_x_at | -0.7252 | 0.5579 | |
| GSE20347 | MYEF2 | 50804 | 222153_at | -0.0453 | 0.3051 | |
| GSE23400 | MYEF2 | 50804 | 222153_at | -0.0838 | 0.0000 | |
| GSE26886 | MYEF2 | 50804 | 232676_x_at | 0.5621 | 0.1853 | |
| GSE29001 | MYEF2 | 50804 | 222153_at | 0.0511 | 0.7603 | |
| GSE38129 | MYEF2 | 50804 | 222153_at | -0.0638 | 0.1238 | |
| GSE45670 | MYEF2 | 50804 | 232676_x_at | -0.9954 | 0.0396 | |
| GSE53622 | MYEF2 | 50804 | 64308 | -3.5024 | 0.0000 | |
| GSE53624 | MYEF2 | 50804 | 64308 | -2.6532 | 0.0000 | |
| GSE63941 | MYEF2 | 50804 | 232676_x_at | -0.4339 | 0.8266 | |
| GSE77861 | MYEF2 | 50804 | 232676_x_at | 0.2868 | 0.3227 | |
| GSE97050 | MYEF2 | 50804 | A_33_P3641427 | -0.5750 | 0.2046 | |
| SRP064894 | MYEF2 | 50804 | RNAseq | -0.5298 | 0.1691 | |
| SRP133303 | MYEF2 | 50804 | RNAseq | -0.1752 | 0.7338 | |
| SRP159526 | MYEF2 | 50804 | RNAseq | 0.7367 | 0.0586 | |
| SRP193095 | MYEF2 | 50804 | RNAseq | 0.5817 | 0.1256 | |
| SRP219564 | MYEF2 | 50804 | RNAseq | -0.7970 | 0.3617 | |
| TCGA | MYEF2 | 50804 | RNAseq | -0.9803 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MYEF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYEF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYEF2 | 50804 | 5 | 3 | 22 | |
| GSE20123 | MYEF2 | 50804 | 5 | 3 | 22 | |
| GSE43470 | MYEF2 | 50804 | 5 | 4 | 34 | |
| GSE46452 | MYEF2 | 50804 | 3 | 7 | 49 | |
| GSE47630 | MYEF2 | 50804 | 8 | 10 | 22 | |
| GSE54993 | MYEF2 | 50804 | 4 | 6 | 60 | |
| GSE54994 | MYEF2 | 50804 | 5 | 7 | 41 | |
| GSE60625 | MYEF2 | 50804 | 4 | 0 | 7 | |
| GSE74703 | MYEF2 | 50804 | 5 | 3 | 28 | |
| GSE74704 | MYEF2 | 50804 | 2 | 3 | 15 | |
| TCGA | MYEF2 | 50804 | 10 | 18 | 68 |
Total number of gains: 56; Total number of losses: 64; Total Number of normals: 368.
Somatic mutations of MYEF2:
Generating mutation plots.
Highly correlated genes for MYEF2:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYEF2 | KLHL23 | 0.829148 | 3 | 0 | 3 |
| MYEF2 | TSPYL2 | 0.815942 | 3 | 0 | 3 |
| MYEF2 | SLC35F1 | 0.811617 | 3 | 0 | 3 |
| MYEF2 | ZMAT4 | 0.78065 | 5 | 0 | 5 |
| MYEF2 | RGMB | 0.774513 | 3 | 0 | 3 |
| MYEF2 | GABARAPL1 | 0.773782 | 3 | 0 | 3 |
| MYEF2 | F8 | 0.768383 | 3 | 0 | 3 |
| MYEF2 | LRCH2 | 0.76788 | 3 | 0 | 3 |
| MYEF2 | ITPK1 | 0.761132 | 3 | 0 | 3 |
| MYEF2 | FRY | 0.755154 | 4 | 0 | 4 |
| MYEF2 | RNF115 | 0.749465 | 3 | 0 | 3 |
| MYEF2 | ADAMTS5 | 0.743383 | 3 | 0 | 3 |
| MYEF2 | IQSEC1 | 0.733739 | 3 | 0 | 3 |
| MYEF2 | MAGEH1 | 0.731315 | 3 | 0 | 3 |
| MYEF2 | MCAM | 0.728749 | 3 | 0 | 3 |
| MYEF2 | UBXN10 | 0.728569 | 3 | 0 | 3 |
| MYEF2 | ARHGEF25 | 0.727334 | 4 | 0 | 4 |
| MYEF2 | TCEA2 | 0.726569 | 4 | 0 | 4 |
| MYEF2 | MPDZ | 0.723498 | 5 | 0 | 5 |
| MYEF2 | FGF12 | 0.722784 | 3 | 0 | 3 |
For details and further investigation, click here
