| Full name: zinc finger and BTB domain containing 1 | Alias Symbol: KIAA0997|ZNF909 | ||
| Type: protein-coding gene | Cytoband: 14q23.3 | ||
| Entrez ID: 22890 | HGNC ID: HGNC:20259 | Ensembl Gene: ENSG00000126804 | OMIM ID: 616578 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB1 | 22890 | 213376_at | -0.0139 | 0.9823 | |
| GSE20347 | ZBTB1 | 22890 | 213376_at | 0.2816 | 0.1339 | |
| GSE23400 | ZBTB1 | 22890 | 213376_at | 0.5646 | 0.0000 | |
| GSE26886 | ZBTB1 | 22890 | 213376_at | -0.5702 | 0.0235 | |
| GSE29001 | ZBTB1 | 22890 | 213376_at | 0.3876 | 0.1952 | |
| GSE38129 | ZBTB1 | 22890 | 213376_at | 0.2999 | 0.0228 | |
| GSE45670 | ZBTB1 | 22890 | 213376_at | 0.0037 | 0.9821 | |
| GSE53622 | ZBTB1 | 22890 | 104217 | 0.1567 | 0.0255 | |
| GSE53624 | ZBTB1 | 22890 | 104217 | 0.1102 | 0.2153 | |
| GSE63941 | ZBTB1 | 22890 | 213376_at | -0.0582 | 0.8883 | |
| GSE77861 | ZBTB1 | 22890 | 213376_at | 0.0956 | 0.8465 | |
| GSE97050 | ZBTB1 | 22890 | A_24_P64918 | 0.2555 | 0.6628 | |
| SRP007169 | ZBTB1 | 22890 | RNAseq | 0.0288 | 0.9248 | |
| SRP008496 | ZBTB1 | 22890 | RNAseq | 0.3434 | 0.1728 | |
| SRP064894 | ZBTB1 | 22890 | RNAseq | 0.1589 | 0.5418 | |
| SRP133303 | ZBTB1 | 22890 | RNAseq | 0.2273 | 0.1919 | |
| SRP159526 | ZBTB1 | 22890 | RNAseq | -0.3189 | 0.0874 | |
| SRP193095 | ZBTB1 | 22890 | RNAseq | 0.0207 | 0.8036 | |
| SRP219564 | ZBTB1 | 22890 | RNAseq | 0.0977 | 0.7589 | |
| TCGA | ZBTB1 | 22890 | RNAseq | -0.0884 | 0.0660 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB1 | 22890 | 7 | 3 | 20 | |
| GSE20123 | ZBTB1 | 22890 | 7 | 3 | 20 | |
| GSE43470 | ZBTB1 | 22890 | 8 | 2 | 33 | |
| GSE46452 | ZBTB1 | 22890 | 16 | 3 | 40 | |
| GSE47630 | ZBTB1 | 22890 | 11 | 9 | 20 | |
| GSE54993 | ZBTB1 | 22890 | 3 | 9 | 58 | |
| GSE54994 | ZBTB1 | 22890 | 18 | 5 | 30 | |
| GSE60625 | ZBTB1 | 22890 | 0 | 2 | 9 | |
| GSE74703 | ZBTB1 | 22890 | 7 | 2 | 27 | |
| GSE74704 | ZBTB1 | 22890 | 3 | 2 | 15 | |
| TCGA | ZBTB1 | 22890 | 32 | 14 | 50 |
Total number of gains: 112; Total number of losses: 54; Total Number of normals: 322.
Somatic mutations of ZBTB1:
Generating mutation plots.
Highly correlated genes for ZBTB1:
Showing top 20/367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB1 | PRPF38A | 0.814652 | 3 | 0 | 3 |
| ZBTB1 | FGGY | 0.808407 | 3 | 0 | 3 |
| ZBTB1 | WDR37 | 0.792502 | 3 | 0 | 3 |
| ZBTB1 | PARG | 0.791681 | 3 | 0 | 3 |
| ZBTB1 | ZKSCAN5 | 0.776845 | 3 | 0 | 3 |
| ZBTB1 | ZNF564 | 0.776025 | 3 | 0 | 3 |
| ZBTB1 | CNOT10 | 0.768745 | 3 | 0 | 3 |
| ZBTB1 | NDUFS3 | 0.754656 | 3 | 0 | 3 |
| ZBTB1 | MRPL37 | 0.749897 | 3 | 0 | 3 |
| ZBTB1 | POLR2K | 0.746225 | 3 | 0 | 3 |
| ZBTB1 | KIAA1324L | 0.744052 | 3 | 0 | 3 |
| ZBTB1 | ZNF627 | 0.742885 | 4 | 0 | 3 |
| ZBTB1 | MKRN1 | 0.738227 | 3 | 0 | 3 |
| ZBTB1 | ZNF268 | 0.731422 | 3 | 0 | 3 |
| ZBTB1 | ZNF354C | 0.731386 | 3 | 0 | 3 |
| ZBTB1 | IFT46 | 0.720534 | 3 | 0 | 3 |
| ZBTB1 | DRAM2 | 0.72008 | 3 | 0 | 3 |
| ZBTB1 | RCAN3 | 0.706729 | 3 | 0 | 3 |
| ZBTB1 | MYSM1 | 0.705915 | 4 | 0 | 4 |
| ZBTB1 | OMA1 | 0.704233 | 3 | 0 | 3 |
For details and further investigation, click here
