| Full name: mitochondrial ribosomal protein L37 | Alias Symbol: RPML2|MRP-L2 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 51253 | HGNC ID: HGNC:14034 | Ensembl Gene: ENSG00000116221 | OMIM ID: 611843 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL37 | 51253 | 222993_at | 0.2414 | 0.7074 | |
| GSE26886 | MRPL37 | 51253 | 222993_at | -0.5652 | 0.0080 | |
| GSE45670 | MRPL37 | 51253 | 222993_at | 0.2105 | 0.1739 | |
| GSE53622 | MRPL37 | 51253 | 77143 | 0.2913 | 0.0002 | |
| GSE53624 | MRPL37 | 51253 | 77143 | 0.4421 | 0.0000 | |
| GSE63941 | MRPL37 | 51253 | 222993_at | 1.3782 | 0.0049 | |
| GSE77861 | MRPL37 | 51253 | 222993_at | -0.2395 | 0.3947 | |
| GSE97050 | MRPL37 | 51253 | A_23_P135474 | 0.3102 | 0.2782 | |
| SRP007169 | MRPL37 | 51253 | RNAseq | -0.1930 | 0.6493 | |
| SRP008496 | MRPL37 | 51253 | RNAseq | -0.5240 | 0.0489 | |
| SRP064894 | MRPL37 | 51253 | RNAseq | 0.4738 | 0.0706 | |
| SRP133303 | MRPL37 | 51253 | RNAseq | 0.3331 | 0.0620 | |
| SRP159526 | MRPL37 | 51253 | RNAseq | 0.3530 | 0.3428 | |
| SRP193095 | MRPL37 | 51253 | RNAseq | -0.0343 | 0.7808 | |
| SRP219564 | MRPL37 | 51253 | RNAseq | 0.2550 | 0.4517 | |
| TCGA | MRPL37 | 51253 | RNAseq | 0.1223 | 0.0124 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL37 | 51253 | 3 | 5 | 22 | |
| GSE20123 | MRPL37 | 51253 | 3 | 4 | 23 | |
| GSE43470 | MRPL37 | 51253 | 6 | 2 | 35 | |
| GSE46452 | MRPL37 | 51253 | 2 | 1 | 56 | |
| GSE47630 | MRPL37 | 51253 | 8 | 4 | 28 | |
| GSE54993 | MRPL37 | 51253 | 0 | 0 | 70 | |
| GSE54994 | MRPL37 | 51253 | 10 | 2 | 41 | |
| GSE60625 | MRPL37 | 51253 | 0 | 0 | 11 | |
| GSE74703 | MRPL37 | 51253 | 4 | 1 | 31 | |
| GSE74704 | MRPL37 | 51253 | 2 | 0 | 18 | |
| TCGA | MRPL37 | 51253 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 37; Total Number of normals: 403.
Somatic mutations of MRPL37:
Generating mutation plots.
Highly correlated genes for MRPL37:
Showing top 20/817 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL37 | KTI12 | 0.822456 | 3 | 0 | 3 |
| MRPL37 | ATF1 | 0.80376 | 3 | 0 | 3 |
| MRPL37 | CLP1 | 0.795228 | 4 | 0 | 4 |
| MRPL37 | ZNF318 | 0.790317 | 3 | 0 | 3 |
| MRPL37 | MRPS14 | 0.784848 | 3 | 0 | 3 |
| MRPL37 | NUP50 | 0.776423 | 3 | 0 | 3 |
| MRPL37 | SRBD1 | 0.774075 | 3 | 0 | 3 |
| MRPL37 | PSMD1 | 0.771054 | 3 | 0 | 3 |
| MRPL37 | SLC25A40 | 0.766942 | 3 | 0 | 3 |
| MRPL37 | PPIL1 | 0.764403 | 4 | 0 | 4 |
| MRPL37 | HMG20A | 0.763793 | 3 | 0 | 3 |
| MRPL37 | PRPF38A | 0.76286 | 6 | 0 | 6 |
| MRPL37 | PITHD1 | 0.761287 | 3 | 0 | 3 |
| MRPL37 | COX15 | 0.755483 | 3 | 0 | 3 |
| MRPL37 | UBE3C | 0.755432 | 3 | 0 | 3 |
| MRPL37 | MRPL38 | 0.754897 | 4 | 0 | 4 |
| MRPL37 | DRAP1 | 0.752227 | 3 | 0 | 3 |
| MRPL37 | ZBTB1 | 0.749897 | 3 | 0 | 3 |
| MRPL37 | UNC5B | 0.749196 | 3 | 0 | 3 |
| MRPL37 | USP37 | 0.746212 | 3 | 0 | 3 |
For details and further investigation, click here
