| Full name: pre-mRNA processing factor 38A | Alias Symbol: FLJ14936|Prp38 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 84950 | HGNC ID: HGNC:25930 | Ensembl Gene: ENSG00000134748 | OMIM ID: 617031 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPF38A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPF38A | 84950 | 1553709_a_at | -0.0570 | 0.9245 | |
| GSE26886 | PRPF38A | 84950 | 1553709_a_at | -0.6910 | 0.0000 | |
| GSE45670 | PRPF38A | 84950 | 1553709_a_at | 0.1179 | 0.4302 | |
| GSE53622 | PRPF38A | 84950 | 51446 | -0.2202 | 0.0051 | |
| GSE53624 | PRPF38A | 84950 | 51446 | 0.0216 | 0.7210 | |
| GSE63941 | PRPF38A | 84950 | 1553709_a_at | 1.4151 | 0.0005 | |
| GSE77861 | PRPF38A | 84950 | 1553709_a_at | -0.3531 | 0.2046 | |
| GSE97050 | PRPF38A | 84950 | A_24_P97001 | -0.4540 | 0.1568 | |
| SRP007169 | PRPF38A | 84950 | RNAseq | -0.4299 | 0.2500 | |
| SRP008496 | PRPF38A | 84950 | RNAseq | -0.5554 | 0.0096 | |
| SRP064894 | PRPF38A | 84950 | RNAseq | -0.0822 | 0.5372 | |
| SRP133303 | PRPF38A | 84950 | RNAseq | -0.0137 | 0.9069 | |
| SRP159526 | PRPF38A | 84950 | RNAseq | 0.0469 | 0.8969 | |
| SRP193095 | PRPF38A | 84950 | RNAseq | -0.2376 | 0.0199 | |
| SRP219564 | PRPF38A | 84950 | RNAseq | 0.1087 | 0.6729 | |
| TCGA | PRPF38A | 84950 | RNAseq | 0.0670 | 0.1935 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRPF38A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPF38A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPF38A | 84950 | 3 | 4 | 23 | |
| GSE20123 | PRPF38A | 84950 | 3 | 3 | 24 | |
| GSE43470 | PRPF38A | 84950 | 5 | 2 | 36 | |
| GSE46452 | PRPF38A | 84950 | 2 | 1 | 56 | |
| GSE47630 | PRPF38A | 84950 | 8 | 4 | 28 | |
| GSE54993 | PRPF38A | 84950 | 0 | 1 | 69 | |
| GSE54994 | PRPF38A | 84950 | 11 | 2 | 40 | |
| GSE60625 | PRPF38A | 84950 | 0 | 0 | 11 | |
| GSE74703 | PRPF38A | 84950 | 4 | 1 | 31 | |
| GSE74704 | PRPF38A | 84950 | 2 | 0 | 18 | |
| TCGA | PRPF38A | 84950 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of PRPF38A:
Generating mutation plots.
Highly correlated genes for PRPF38A:
Showing top 20/514 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPF38A | KIAA0556 | 0.853394 | 3 | 0 | 3 |
| PRPF38A | GLUD2 | 0.826536 | 4 | 0 | 4 |
| PRPF38A | WBP2 | 0.823791 | 3 | 0 | 3 |
| PRPF38A | COX15 | 0.820782 | 3 | 0 | 3 |
| PRPF38A | MUL1 | 0.817586 | 3 | 0 | 3 |
| PRPF38A | MIPEP | 0.81594 | 3 | 0 | 3 |
| PRPF38A | ZBTB1 | 0.814652 | 3 | 0 | 3 |
| PRPF38A | PPCS | 0.813389 | 4 | 0 | 4 |
| PRPF38A | POLE3 | 0.806682 | 4 | 0 | 4 |
| PRPF38A | DALRD3 | 0.802393 | 3 | 0 | 3 |
| PRPF38A | ASH2L | 0.802014 | 3 | 0 | 3 |
| PRPF38A | VPS26A | 0.798036 | 4 | 0 | 4 |
| PRPF38A | ZFC3H1 | 0.792567 | 3 | 0 | 3 |
| PRPF38A | LMBR1 | 0.792446 | 3 | 0 | 3 |
| PRPF38A | MAPK1 | 0.789336 | 3 | 0 | 3 |
| PRPF38A | MORC3 | 0.784051 | 3 | 0 | 3 |
| PRPF38A | ATP8B1 | 0.780919 | 3 | 0 | 3 |
| PRPF38A | TRAFD1 | 0.780597 | 3 | 0 | 3 |
| PRPF38A | CPPED1 | 0.780446 | 3 | 0 | 3 |
| PRPF38A | RNLS | 0.779682 | 3 | 0 | 3 |
For details and further investigation, click here
