| Full name: intraflagellar transport 46 | Alias Symbol: C11orf2|FLJ21827|CFAP32 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 56912 | HGNC ID: HGNC:26146 | Ensembl Gene: ENSG00000118096 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IFT46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT46 | 56912 | 218483_s_at | -0.1605 | 0.6066 | |
| GSE20347 | IFT46 | 56912 | 218483_s_at | -0.0085 | 0.9525 | |
| GSE23400 | IFT46 | 56912 | 218483_s_at | -0.0413 | 0.4700 | |
| GSE26886 | IFT46 | 56912 | 218483_s_at | -0.8279 | 0.0062 | |
| GSE29001 | IFT46 | 56912 | 218483_s_at | -0.1745 | 0.4609 | |
| GSE38129 | IFT46 | 56912 | 218483_s_at | -0.0438 | 0.7066 | |
| GSE45670 | IFT46 | 56912 | 218483_s_at | -0.1203 | 0.3406 | |
| GSE53622 | IFT46 | 56912 | 20563 | -0.0101 | 0.9239 | |
| GSE53624 | IFT46 | 56912 | 20563 | -0.0098 | 0.9468 | |
| GSE63941 | IFT46 | 56912 | 218483_s_at | -0.7016 | 0.2740 | |
| GSE77861 | IFT46 | 56912 | 218483_s_at | -0.0827 | 0.7919 | |
| GSE97050 | IFT46 | 56912 | A_23_P116207 | -0.0628 | 0.8245 | |
| SRP007169 | IFT46 | 56912 | RNAseq | -0.2550 | 0.6513 | |
| SRP008496 | IFT46 | 56912 | RNAseq | 0.3876 | 0.3089 | |
| SRP064894 | IFT46 | 56912 | RNAseq | -0.0386 | 0.8566 | |
| SRP133303 | IFT46 | 56912 | RNAseq | -0.4979 | 0.0012 | |
| SRP159526 | IFT46 | 56912 | RNAseq | 0.2202 | 0.4997 | |
| SRP193095 | IFT46 | 56912 | RNAseq | -0.4527 | 0.0014 | |
| SRP219564 | IFT46 | 56912 | RNAseq | -0.2795 | 0.4068 | |
| TCGA | IFT46 | 56912 | RNAseq | -0.0956 | 0.2007 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFT46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT46 | 56912 | 2 | 11 | 17 | |
| GSE20123 | IFT46 | 56912 | 2 | 11 | 17 | |
| GSE43470 | IFT46 | 56912 | 2 | 9 | 32 | |
| GSE46452 | IFT46 | 56912 | 3 | 26 | 30 | |
| GSE47630 | IFT46 | 56912 | 2 | 19 | 19 | |
| GSE54993 | IFT46 | 56912 | 10 | 0 | 60 | |
| GSE54994 | IFT46 | 56912 | 5 | 19 | 29 | |
| GSE60625 | IFT46 | 56912 | 0 | 3 | 8 | |
| GSE74703 | IFT46 | 56912 | 1 | 6 | 29 | |
| GSE74704 | IFT46 | 56912 | 1 | 7 | 12 | |
| TCGA | IFT46 | 56912 | 4 | 51 | 41 |
Total number of gains: 32; Total number of losses: 162; Total Number of normals: 294.
Somatic mutations of IFT46:
Generating mutation plots.
Highly correlated genes for IFT46:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT46 | EXOC4 | 0.830506 | 3 | 0 | 3 |
| IFT46 | RABGAP1L | 0.808457 | 3 | 0 | 3 |
| IFT46 | ARL16 | 0.805035 | 3 | 0 | 3 |
| IFT46 | WASL | 0.793234 | 3 | 0 | 3 |
| IFT46 | ALKBH7 | 0.781122 | 3 | 0 | 3 |
| IFT46 | RGS18 | 0.776028 | 3 | 0 | 3 |
| IFT46 | NDUFS2 | 0.765754 | 3 | 0 | 3 |
| IFT46 | LMBR1 | 0.76527 | 3 | 0 | 3 |
| IFT46 | MORC3 | 0.756824 | 3 | 0 | 3 |
| IFT46 | TRAPPC2 | 0.753106 | 3 | 0 | 3 |
| IFT46 | WHAMM | 0.747576 | 3 | 0 | 3 |
| IFT46 | ZNF22 | 0.742124 | 3 | 0 | 3 |
| IFT46 | NCOR1 | 0.741427 | 4 | 0 | 3 |
| IFT46 | GSTT2 | 0.737416 | 3 | 0 | 3 |
| IFT46 | ZNF862 | 0.73624 | 3 | 0 | 3 |
| IFT46 | MTRF1L | 0.729018 | 3 | 0 | 3 |
| IFT46 | GPD1L | 0.725874 | 3 | 0 | 3 |
| IFT46 | FAM32A | 0.725134 | 3 | 0 | 3 |
| IFT46 | UBE2N | 0.723354 | 3 | 0 | 3 |
| IFT46 | TMEM218 | 0.723253 | 7 | 0 | 7 |
For details and further investigation, click here
